Results 31 to 40 of about 361,490 (238)

Assessing Population Structure and Signatures of Selection in Wanbei Pigs Using Whole Genome Resequencing Data

Animals, 2022
Wanbei pig (WBP) is one of the indigenous pig resources in China and has many germplasm characteristics. However, research on its genome is lacking. To assess the genomic variation, population structure, and selection signatures, we resequenced 18 WBP ...
Wei Zhang, Linqing Liu, Mei Zhou, Shiguang Su, Lin Dong, Xinxin Meng, Xueting Li, Chonglong Wang   +7 more
doaj   +1 more source

COMPARISON OF QUANTITATIVE GENETIC PARAMETERS [PDF]

Evolution, 1992
Shaw (1991) has described a maximum-likelihood procedure for comparing genetic covariance matrices between populations. While her efforts to expand the procedures available for quantitative genetic analyses are laudable, her discussion is incomplete in several respects. For example, consider her criticism of Dietz's matrix permutation test (Dietz, 1983)
David E, Cowley, William R, Atchley
openaire   +2 more sources

Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig, Sophie Jessop, Jordan R. Hansford, Hien Le, Matthew O'Connor, Peter Gorayski, Andrew Cunningham, Amanda Hutchinson, Victoria Bedford, Eva Bezak, Nayana Parange, Kelly Skelton, Timothy Price, Michala Short   +13 more
wiley   +1 more source

Evaluation of the Utility of Baseline Echocardiogram in Patients With Standard Risk Precursor B‐Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
Abstract Background A routine baseline echocardiogram is often obtained prior to anthracycline administration in children with cancer. The utility of baseline echocardiogram is unclear in patients with standard risk B‐cell acute lymphoblastic leukemia (SR B‐ALL) as their anthracycline cumulative dose is low.
Ziyad Alrajhi, Alice Pozza, Luc Mertens, Adam Paul Yan, Sarah Alexander   +4 more
wiley   +1 more source

The effect of phenotyping, adult selection, and mating strategies on genetic gain and rate of inbreeding in black soldier fly breeding programs

Genetics Selection Evolution
Background The aim of this study was to compare genetic gain and rate of inbreeding for different mass selection breeding programs with the aim of increasing larval body weight (LBW) in black soldier flies. The breeding programs differed in: (1) sampling
Margot Slagboom, Hanne Marie Nielsen, Morten Kargo, Mark Henryon, Laura Skrubbeltrang Hansen   +4 more
doaj   +1 more source

Multiple Trait Covariance Association Test Identifies Gene Ontology Categories Associated with Chill Coma Recovery Time in Drosophila melanogaster

Scientific Reports, 2017
The genomic best linear unbiased prediction (GBLUP) model has proven to be useful for prediction of complex traits as well as estimation of population genetic parameters.
Izel Fourie Sørensen, Stefan M. Edwards, Palle Duun Rohde, Peter Sørensen   +3 more
doaj   +1 more source

Contribution of rare and low-frequency whole-genome sequence variants to complex traits variation in dairy cattle

Genetics Selection Evolution, 2017
Background Whole-genome sequencing and imputation methodologies have enabled the study of the effects of genomic variants with low to very low minor allele frequency (MAF) on variation in complex traits.
Qianqian Zhang, Mario P. L. Calus, Bernt Guldbrandtsen, Mogens Sandø Lund, Goutam Sahana   +4 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Weighted single-step genomic best linear unbiased prediction integrating variants selected from sequencing data by association and bioinformatics analyses

Genetics Selection Evolution, 2020
Background Sequencing data enable the detection of causal loci or single nucleotide polymorphisms (SNPs) highly linked to causal loci to improve genomic prediction.
Aoxing Liu, Mogens Sandø Lund, Didier Boichard, Emre Karaman, Bernt Guldbrandtsen, Sebastien Fritz, Gert Pedersen Aamand, Ulrik Sander Nielsen, Goutam Sahana, Yachun Wang, Guosheng Su   +10 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source