Results 41 to 50 of about 4,302,850 (309)

The Effect of Using Organic or Conventional Sires on Genetic Gain in Organic Pigs: A Simulation Study

Animals, 2022
Current organic pig-breeding programs use pigs from conventional breeding populations. However, there are considerable differences between conventional and organic production systems.
Roos Marina Zaalberg, Hanne Marie Nielsen, Anders Christian Sørensen, Thinh T. Chu, Just Jensen, Trine Michelle Villumsen   +5 more
doaj   +1 more source

Large-scale plasma proteomics comparisons through genetics and disease associations

Nature, 2023
Comparisons of phenotypic and genetic association with protein levels from Icelandic and UK Biobank cohorts show that using multiple analysis platforms and stratifying populations by ancestry improves the detection of associations and allows the ...
Grimur Hjorleifsson Eldjarn, E. Ferkingstad, S. Lund, H. Helgason, O. Magnusson, Kristbjorg Gunnarsdottir, T. Olafsdottir, B. Halldórsson, Pall I. Olason, Florian Zink, S. A. Gudjonsson, G. Sveinbjornsson, Magnus I. Magnusson, Agnar Helgason, A. Oddsson, G. Halldorsson, Magnus K. Magnusson, S. Saevarsdottir, Thjodbjorg Eiriksdottir, G. Másson, H. Stefánsson, I. Jónsdóttir, H. Hólm, T. Rafnar, P. Melsted, J. Saemundsdottir, G. Norddahl, G. Thorleifsson, M. O. Ulfarsson, D. Gudbjartsson, U. Thorsteinsdóttir, P. Sulem, K. Stefánsson   +32 more
semanticscholar   +1 more source

Benefits of testing in both bio-secure and production environments in genomic selection breeding programs for commercial broiler chicken

Genetics Selection Evolution, 2018
Background A breeding program for commercial broiler chicken that is carried out under strict biosecure conditions can show reduced genetic gain due to genotype by environment interactions (G × E) between bio-secure (B) and commercial production (C ...
Thinh T. Chu, Setegn W. Alemu, Elise Norberg, Anders C. Sørensen, John Henshall, Rachel Hawken, Just Jensen   +6 more
doaj   +1 more source

Segregation between breeds and local breed proportions in genetic and genomic models for crossbreds

Genetics Selection Evolution, 2023
Background The breeding value of a crossbred individual can be expressed as the sum of the contributions from each of the contributing pure breeds.
Jón H. Eiríksson, Guosheng Su, Ismo Strandén, Ole F. Christensen   +3 more
doaj   +1 more source

Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets

Nature Immunology, 2023
Here the authors identify genetic effectors of the level of inflammation-related plasma proteins and use Mendelian randomization to identify proteins that contribute to immune-mediated disease risk.
Jinghua Zhao, D. Stacey, N. Eriksson, E. Macdonald-Dunlop, Å. Hedman, A. Kalnapenkis, Stefan Enroth, D. Cozzetto, J. Digby-Bell, J. Marten, L. Folkersen, C. Herder, L. Jonsson, Sarah E. Bergen, C. Gieger, E. Needham, P. Surendran, D. Paul, O. Polašek, B. Thorand, H. Grallert, M. Roden, U. Võsa, T. Esko, C. Hayward, Å. Johansson, U. Gyllensten, N. Powell, O. Hansson, N. Mattsson‐Carlgren, Peter K. Joshi, J. Danesh, L. Padyukov, Lars Klareskog, M. Landén, James F. Wilson, A. Siegbahn, L. Wallentin, A. Mälarstig, A. Butterworth, J. Peters   +40 more
semanticscholar   +1 more source

The MedSupport Multilevel Intervention to Enhance Support for Pediatric Medication Adherence: Development and Feasibility Testing

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction We developed MedSupport, a multilevel medication adherence intervention designed to address root barriers to medication adherence. This study sought to explore the feasibility and acceptability of the MedSupport intervention strategies to support a future full‐scale randomized controlled trial.
Elizabeth G. Bouchard, Hital Patel, Paula C. Vincent, Justine Kahn, Kira Bona, Thai Hoa Tran, Elisa M. Rodriguez, Kristopher Attwood, Kara M. Kelly   +8 more
wiley   +1 more source

RETRACTED ARTICLE: Dissecting closely linked association signals in combination with the mammalian phenotype database can identify candidate genes in dairy cattle

BMC Genetics, 2018
Background Genome-wide association studies (GWAS) have been successfully implemented in cattle research and breeding. However, moving from the associations to identifying the causal variants and revealing underlying mechanisms have proven complicated. In
Zexi Cai, Bernt Guldbrandtsen, Mogens Sandø Lund, Goutam Sahana   +3 more
doaj   +1 more source

Quantitative Genetics of the Maize Leaf Microbiome

, 2018
The degree to which the genotype of an organism can affect the composition of its associated microbial communities (“microbiome”) varies by organism and habitat, and in many cases is unknown.
Jason G. Wallace, Karl A. G. Kremling, L. Kovar, E. Buckler   +3 more
semanticscholar   +1 more source

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source

Impact of rare and low-frequency sequence variants on reliability of genomic prediction in dairy cattle

Genetics Selection Evolution, 2018
Background Availability of whole-genome sequence data for a large number of cattle and efficient imputation methodologies open a new opportunity to include rare and low-frequency variants (RLFV) in genomic prediction in dairy cattle.
Qianqian Zhang, Goutam Sahana, Guosheng Su, Bernt Guldbrandtsen, Mogens Sandø Lund, Mario P. L. Calus   +5 more
doaj   +1 more source