Impulsivity is a heritable trait in rodents and associated with a novel quantitative trait locus on chromosome 1 [PDF]
AbstractImpulsivity describes the tendency to act prematurely without appropriate foresight and is symptomatic of a number of neuropsychiatric disorders. Although a number of genes for impulsivity have been identified, no study to date has carried out an unbiased, genome-wide approach to identify genetic markers associated with impulsivity in ...
Gunter Schumann+22 more
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Heritability Estimates of Some Quantitative Traits in Potatoes [PDF]
Broad-sense heritability (H) values of some quantitative traits in a potato population comprising 21 genotypes grown at Bornova, Izmir, Turkey during the 2013 and 2014 growing seasons were estimated by using the variance components analysis method. Based on the combined analysis of variance performed over two years, the following moderate to high level
OZTURK, Gulsum, YILDIRIM, Zihin
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Heritability and Tissue Specificity of Expression Quantitative Trait Loci [PDF]
Variation in gene expression is heritable and has been mapped to the genome in humans and model organisms as expression quantitative trait loci (eQTLs). We applied integrated genome-wide expression profiling and linkage analysis to the regulation of gene expression in fat, kidney, adrenal, and heart tissues using the BXH/HXB panel of rat recombinant ...
Judith Fischer+13 more
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Niche construction in quantitative traits: heritability and response to selection
A central tenet of niche construction (NC) theory is that organisms can alter their environments in heritable and evolutionarily important ways, often altering selection pressures. We suggest that the physical changes niche constructors make to their environments may also alter trait heritability and the response of phenotypes to selection. This effect
Laurel Fogarty, Michael J. Wade
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Broad and Narrow Heritabilities of Quantitative Traits in a Founder Population [PDF]
Estimation of the components of variance for a quantitative trait allows one to evaluate both the degree to which genetics influences the trait and the trait's underlying genetic architecture. For particular traits, the estimates also may have implications for discriminating between potential models of selection and for choosing an appropriate model ...
Carole Ober+2 more
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The role of heritability in mapping expression quantitative trait loci [PDF]
Abstract Gene expression, as a heritable complex trait, has recently been used in many genome-wide linkage studies. The estimated overall heritability of each trait may be considered as evidence of a genetic contribution to the total phenotypic variation, which implies the possibility of mapping genome regions responsible for the gene ...
David H Ballard, Song Huang, Hongyu Zhao
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Quantitative trait loci and transcriptome signatures associated with avian heritable resistance to Campylobacter [PDF]
AbstractCampylobacter is the leading cause of bacterial foodborne gastroenteritis worldwide. Handling or consumption of contaminated poultry meat is a key risk factor for human campylobacteriosis. One potential control strategy is to select poultry with increased resistance to Campylobacter. We associated high-density genome-wide genotypes (600K single
Lisa Rothwell+21 more
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The lipoprotein subfraction profile: heritability and identification of quantitative trait loci [PDF]
The HDL and LDL subclass profile is an emerging cardiovascular risk factor. Yet, the biological and genetic mechanisms controlling the lipoprotein subclass distribution are unclear. Therefore, we aimed 1) to determine the heritability of the entire spectrum of LDL and HDL subclass features and 2) to identify gene loci influencing the lipoprotein ...
Guenter Riegger+9 more
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Heritability and quantitative genetic divergence of serotiny, a fire-persistence plant trait [PDF]
Although it is well known that fire acts as a selective pressure shaping plant phenotypes, there are no quantitative estimates of the heritability of any trait related to plant persistence under recurrent fires, such as serotiny. In this study, the heritability of serotiny in Pinus halepensis is calculated, and an evaluation is made as to whether fire ...
Hernández-Serrano, Ana+5 more
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Explaining the heritability of an ecologically significant trait in terms of individual quantitative trait loci [PDF]
Most natural populations display substantial genetic variation in behaviour, morphology, physiology, life history and the susceptibility to disease. A major challenge is to determine the contributions of individual loci to variation in complex traits.
John H. Willis+3 more
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