Results 1 to 10 of about 21,627 (244)
Quantitative trait loci and transcriptome signatures associated with avian heritable resistance to Campylobacter [PDF]
Scientific Reports, 2021 Campylobacter is the leading cause of bacterial foodborne gastroenteritis worldwide. Handling or consumption of contaminated poultry meat is a key risk factor for human campylobacteriosis.
Androniki Psifidi +16 more
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Heritability and tissue specificity of expression quantitative trait loci. [PDF]
PLoS Genetics, 2006 Variation in gene expression is heritable and has been mapped to the genome in humans and model organisms as expression quantitative trait loci (eQTLs). We applied integrated genome-wide expression profiling and linkage analysis to the regulation of gene
Enrico Petretto +11 more
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Niche construction in quantitative traits: heritability and response to selection
Proceedings of the Royal Society B: Biological Sciences, 2022 A central tenet of niche construction (NC) theory is that organisms can alter their environments in heritable and evolutionarily important ways, often altering selection pressures. We suggest that the physical changes niche constructors make to their environments may also alter trait heritability and the response of phenotypes to selection. This effect
Laurel Fogarty, Michael J. Wade
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Heritability of bipolar affective disorder: Family study [PDF]
Vojnosanitetski Pregled, 2011 Background/Aim. Bipolar affective disorder is mental disorder with polygenic type of heredity. Heritability - relation between genetic and environmental variance is used to estimate the level of influence of genetic variance to phenotype variance ...
Obradović Tanja +3 more
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Frontiers in Genetics, 2023 Introduction: Porcine reproductive and respiratory syndrome virus (PRRSV) causes respiratory disease in piglets and reproductive disease in sows. Piglet and fetal serum thyroid hormone (i.e., T3 and T4) levels decrease rapidly in response to Porcine ...
Angelica Van Goor +7 more
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Capturing indirect genetic effects on phenotypic variability: Competition meets canalization
Evolutionary Applications, 2022 Phenotypic variability of a genotype is relevant both in natural and domestic populations. In the past two decades, variability has been studied as a heritable quantitative genetic trait in its own right, often referred to as inherited variability or ...
Jovana Marjanovic +4 more
doaj +1 more source
Mapping determinants of gene expression plasticity by genetical genomics in C. elegans. [PDF]
PLoS Genetics, 2006 Recent genetical genomics studies have provided intimate views on gene regulatory networks. Gene expression variations between genetically different individuals have been mapped to the causal regulatory regions, termed expression quantitative trait loci.
Yang Li +11 more
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Anterior chamber depth in mice is controlled by several quantitative trait loci.
PLoS ONE, 2023 Anterior chamber depth (ACD) is a quantitative trait associated with primary angle closure glaucoma (PACG). Although ACD is highly heritable, known genetic variations explain a small fraction of the phenotypic variability.
Demelza R Larson +3 more
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The role of heritability in mapping expression quantitative trait loci [PDF]
BMC Proceedings, 2007 Abstract Gene expression, as a heritable complex trait, has recently been used in many genome-wide linkage studies. The estimated overall heritability of each trait may be considered as evidence of a genetic contribution to the total phenotypic variation, which implies the possibility of mapping genome regions responsible for the gene ...
Huang, Song +2 more
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A population genetic interpretation of GWAS findings for human quantitative traits. [PDF]
PLoS Biology, 2018 Human genome-wide association studies (GWASs) are revealing the genetic architecture of anthropomorphic and biomedical traits, i.e., the frequencies and effect sizes of variants that contribute to heritable variation in a trait.
Yuval B Simons +3 more
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