Results 51 to 60 of about 21,627 (244)

Meta‐GWAS of Pig Semen Quality Traits Reveals Conserved Genes Regulating Mammalian Fertility

Advanced Science, EarlyView.
This study incorporated 14 210 individuals to perform a GWAS meta‐analysis of six semen quality traits. The GWAS meta‐analysis identifies 234 GWAS loci associated with semen quality traits. The incorporation with a functional genomics resource explains potential genetic regulation of ∼40% GWAS signals underlying semen quality traits.
Qing Lin, Xiaodian Cai, Zhanming Zhong, Tingting Li, Xinyou Chen, Wondossen Ayalew, Zhiting Xu, Chen Wei, Xiaoke Zhang, Hong Cheng, Zhenyang Zhang, Xuehua Li, Yongjie Tang, Siqian Chen, Jun Zhou, Jinglei Si, Xibo Wu, Chao Ning, Qishan Wang, Yuchun Pan, Yahui Gao, Jiaqi Li, Ying Yu, Zhe Zhang, Yunxiang Zhao, Lingzhao Fang, Zhe Zhang   +26 more
wiley   +1 more source

Heritability of Horn Size in Thinhorn Sheep

Frontiers in Genetics, 2019
Understanding the genetic basis of fitness-related trait variation has long been of great interest to evolutionary biologists. Secondary sexual characteristics, such as horns in bovids, are particularly intriguing since they can be potentially affected ...
Zijian Sim, Zijian Sim, David W. Coltman
doaj   +1 more source

Heritability and gene effects for yield related quantitative traits in eggplant

Annals of Agricultural Sciences, 2016
AbstractKnowledge of gene actions and their relative contribution in expression of characters is of great importance. Therefore, four crosses were made among the six parents viz., Doli-5×GBL-1 (cross 1), Doli-5×KS-331 (cross 2), Pusa Uttam×KS-331 (cross 3) and AB 07-02×GOB 1 (cross 4) to study gene actions responsible for inheritance of twelve fruit ...
Chintan Mistry, Keshubhai B. Kathiria, Srikanth Sabolu, Sushil Kumar   +3 more
openaire   +2 more sources

A Novel 10‐Protein Score for Liver Fat Content Predicts Cardiovascular‐Kidney‐Metabolic Disease Risk

Advanced Science, EarlyView.
A novel 10‐protein plasma score precisely quantifies liver fat, outperforming the fatty liver index. It robustly predicts the risk of numerous cardiovascular‐kidney‐metabolic diseases and integrates with genetic data for precision prevention, offering a practical alternative to magnetic resonance imaging (MRI). Abstract Liver fat content (LFC) is a key
Xiaoqin Gan, Yuanxiu Wei, Yiting Wu, Xinyue Su, Gangling Wang, Sisi Yang, Ziliang Ye, Yanjun Zhang, Hao Xiang, Yu Huang, Yiwei Zhang, Yuanyuan Zhang, Xianhui Qin   +12 more
wiley   +1 more source

Spring Is Coming: Genetic Analyses of the Bud Break Date Locus Reveal Candidate Genes From the Cold Perception Pathway to Dormancy Release in Apple (Malus × domestica Borkh.)

Frontiers in Plant Science, 2019
Chilling requirement (CR) for bud dormancy completion determines the time of bud break in apple (Malus × domestica Borkh.). The molecular control of bud dormancy is highly heritable, suggesting a strong genetic control of the trait. An available Infinium
Yohanna Evelyn Miotto, Carolina Tessele, Ana Beatriz Costa Czermainski, Diogo Denardi Porto, Vítor da Silveira Falavigna, Vítor da Silveira Falavigna, Tiago Sartor, Tiago Sartor, Amanda Malvessi Cattani, Amanda Malvessi Cattani, Carla Andrea Delatorre, Sérgio Amorim de Alencar, Orzenil Bonfim da Silva-Junior, Roberto Coiti Togawa, Marcos Mota do Carmo Costa, Georgios Joannis Pappas, Priscila Grynberg, Paulo Ricardo Dias de Oliveira, Marcus Vinícius Kvitschal, Frederico Denardi, Vanessa Buffon, Luís Fernando Revers, Luís Fernando Revers   +22 more
doaj   +1 more source

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

Advanced Science, EarlyView.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen, Xin Wang, Haifeng Ding, Bosheng Zheng, Keni Zeng, Chuying Hu, Jiayi Liu, Xiao Zhu, Haibing Yu   +8 more
wiley   +1 more source

Variant level heritability estimates of type 2 diabetes in African Americans

Scientific Reports
Type 2 diabetes (T2D) is caused by both genetic and environmental factors and is associated with an increased risk of cardiorenal complications and mortality.
Nicole D. Armstrong, Amit Patki, Vinodh Srinivasasainagendra, Tian Ge, Leslie A. Lange, Leah Kottyan, Bahram Namjou, Amy S. Shah, Laura J. Rasmussen-Torvik, Gail P. Jarvik, James B. Meigs, Elizabeth W. Karlson, Nita A. Limdi, Marguerite R. Irvin, Hemant K. Tiwari   +14 more
doaj   +1 more source

Genetics of the Inverse Relationship between Grain Yield and Grain Protein Content in Common Wheat

Plants, 2022
Grain protein content (GPC) is one of the most important criteria to determine the quality of common wheat (Triticum aestivum). One of the major obstacles for bread wheat production is the negative correlation between GPC and grain yield (GY).
Manuel Geyer, Volker Mohler, Lorenz Hartl   +2 more
doaj   +1 more source

EFFECT OF SELECTION ON HERITABILITY AND GENETIC CORRELATION OF TWO QUANTITATIVE TRAITS IN MICE [PDF]

Canadian Journal of Genetics and Cytology, 1974
The effects of different intensities of single trait directional selection on the heritability and genetic correlation of two quantitative traits in random mating populations of mice were observed during 14 generations. The initial population was divided at random into five groups (A, B, C, D and E).
T K, Cheung, R J, Parker
openaire   +2 more sources

Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits

Advanced Science, EarlyView.
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao, Hanpeng Luo, Dailu Guan, Xuefeng Fu, Feng Wang, Guoming Zhang, Shanglai Li, Hua Yang, Yanli Zhang   +8 more
wiley   +1 more source