Results 41 to 50 of about 8,280 (111)

Molecular Evolution of the H5 and H7 Highly Pathogenic Avian Influenza Virus Haemagglutinin Cleavage Site Motif

Reviews in Medical Virology, Volume 35, Issue 1, January 2025.
ABSTRACT Avian influenza viruses are ubiquitous in the Anatinae subfamily of aquatic birds and occasionally spill over to poultry. Infection with low pathogenicity avian influenza viruses generally leads to subclinical or mild clinical disease. In contrast, highly pathogenic avian influenza viruses emerge from low pathogenic forms and can cause severe ...
Jasmina M. Luczo, Erica Spackman
wiley   +1 more source

Pre-S Deletions are Predominant Quasispecies in HIV/HBV Infection: Quasispecies Perspective.

Infection and drug resistance, 2020
Combined HIV infection can accelerate HBV-induced liver disease. It is known that HBV Pre-S deletion is closely related to HBV-associated terminal liver disease in HBV mono-infection. Currently, data on HBV Pre-S quasispecies feature deletion in HIV/HBV co-infected patients are lacking.The characteristics and blood samples of patients with chronic HBV ...
Nie,Yuan, Deng,Xi-Zi, Lan,Yun, Li,Feng, Hu,Feng-Yu   +4 more
openaire   +4 more sources

Viruses as Quasispecies: Biological Implications [PDF]

, 2006
During viral infections, the complex and dynamic distributions of variants, termed viral quasispecies, play a key role in the adaptability of viruses to changing environments and the fate of the population as a whole. Mutant spectra are continuously and avoidably generated during RNA genome replication, and they are not just a by-product of error-prone
Domingo, E., Martín, V., Perales, C., Grande-Pérez, A., García-Arriaza, J., Arias, A.   +5 more
openaire   +2 more sources

Mutation, Quasispecies, and Lethal Mutagenesis

, 2014
Viral pathogenesis is not alien to the evolutionary history of a virus. Picornaviruses, simply by the fact of sharing a phylogenetic position, need not be associated with similar diseases, reflecting that the nature of the interactions with their host organisms may depend in a subtle manner on minimal genetic change of the virus.
Domingo, Esteban, Perales, Celia, Agudo, Rubén, Arias, Armando, Escarmís, Cristina, Ferrer-Orta, Cristina, Verdaguer, Núria   +6 more
openaire   +2 more sources

The quasispecies distribution

, 2016
The quasispecies model was introduced in 1971 by Manfred Eigen to discuss the first stages of life on Earth. It provides an appealing mathematical framework to study the evolution of populations in biology, for instance viruses. We present briefly the model and we focus on its stationary solutions.
Cerf, Raphaël, Dalmau, Joseba
openaire   +2 more sources

PacBio high-fidelity near full-length genome sequencing for HIV-1 quasispecies: methodological framework and validation. [PDF]

Front Microbiol
Zhu B, Wang X, Li H, Liu Y, Jia L, Wang X, Li J, Zhang B, Han J, Ma W, Li L.   +10 more
europepmc   +1 more source

Evolution of viral genomes and their clouds of sequence. [PDF]

Proc Natl Acad Sci U S A
Kirkegaard K.
europepmc   +1 more source

Consequences of prion strain mixtures: Indifference, competition, or collusion. [PDF]

PLoS Pathog
Woerman AL, Bartz JC.
europepmc   +1 more source

Full-Genome Hepatitis B Virus Genotyping: A Juxtaposition of Next-Generation and Clone-Based Sequencing Approaches-Comparing Genotyping Methods of Hepatitis B Virus. [PDF]

Viruses
Hu LP, Chen QY, Huang ML, Zhang WJ, Huang XQ, Yi XF, Jia HH.   +6 more
europepmc   +1 more source

Viral Quasispecies Inference from Single Observations-Mutagens as Accelerators of Quasispecies Evolution. [PDF]

Microorganisms
Gregori J, Salicrú M, Ibáñez-Lligoña M, Colomer-Castell S, Campos C, González-Camuesco A, Quer J.   +6 more
europepmc   +1 more source