Results 81 to 90 of about 623,955 (160)

Synthesis and Antimalarial Activity of Some New Quinazoline Derivatives

, 1984
Department of Chemical Engineering and Technology, Panjab University, Chandigarh-160 014 Manuscript received 8 April 1982, revised 18 April 1984, accepted 21 July 1984 Dialkylaminoalkylamino and dialkylaminomethylarylamino derivatives of quinazoline ...
I. S. GUPTA, (Miss) N. SINGHAL, P. C. BANSAL   +2 more
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Study of the Anti-klebsiella Activity of Quinazoline Compounds Containing a Piperazine Ring

Антибиотики и Химиотерапия
The aim of this study was to investigate the antimicrobial activity of piperazine ring-containing quinazoline compounds against Klebsiella pneumoniae.
A. A. Tsibizova, A. L. Yasenyavskaya, G. N. Genatullina, A. A. Ozerov, M. A. Samotrueva   +4 more
doaj   +1 more source

A concise and efficient synthesis of benzimidazo[1,2-c]quinazolines through CuI-catalyzed intramolecular N-arylations

Beilstein Journal of Organic Chemistry, 2015
A series of functionalized benzimidazo[1,2-c]quinazoline derivatives was obtained in excellent yields under mild conditions through a CuI-catalyzed Ullmann N-arylation starting from easily available starting materials.
Xinlong Pang, Chao Chen, Ming Li, Chanjuan Xi   +3 more
doaj   +1 more source

Alkylation of 2,4-(1H,3H)-Quinazolinediones with Dialkyl Carbonates Under Microwave Irradiations

Molecules, 2009
Alkylation is a very important chemical reaction which modifies the biological properties of drugs. Quinazolinedione derivatives are of considerable interest due to their wide array of pharmacological properties.We now report application of a practical ...
Martha Cecilia Meza, Jesús Ramón Rodríguez, Karla Alejandra Espinoza, Ignacio Alfredo Rivero, Leticia Guerrero   +4 more
doaj   +1 more source

NEW POTENTIAL ANTI-INFLAMMATORY QUINAZOLINE-2,4(1H,3H)-DIONE DERIVATIVES

Zagazig Journal of Pharmaceutical Sciences, 2001
A series of nucleophilic and condensation reactions were carried out to synthesize 1.3,4-triazolyimethoxyphenyl and 1,3.4-Oxadiazoly1methoxyphenyl derivatives of quinazoline-2,4(1H,3H)-dione as potential anti-inflammatory agents.
Samy Sakr
doaj   +1 more source

Recent Advances on Quinazoline

This book investigates and identifies novel therapeutic compounds for the treatment of a range of illnesses. Heterocyclic compounds are a significant class of substances with biological activity.

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A Novel Highly Stereoselective Synthesis of 2,3-Disubstituted 3H-Quinazoline-4-one Derivatives

, 2016
An efficient three-step synthesis of chiral 3H-quinazoline-4-one derivatives from commercial materials is disclosed. The Mumm reaction of imidoyl chloride with α-amino acids followed by reductive cyclization affords enantiomerically pure (ee >93 ...
Paul Zhichkin (2479966), David Fairfax (1665337), Stephen White (2498947), Angela Judkins (2498941), Matthew Ronsheim (2498938), Jennifer Treiberg (2498932), Hua Chee Ooi (2498950), Edward Kesicki (2498935), Lisa Bourdon (2498944)   +8 more
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A comparative QSAR analysis and molecular docking studies of quinazoline derivatives as tyrosine kinase (EGFR) inhibitors: A rational approach to anticancer drug design

Journal of Saudi Chemical Society, 2011
In this paper, an attempt was made to develop a quantitative structure–activity relationship (2D and 3D QSAR) and molecular docking studies on a series of quinazoline derivatives acting as protein tyrosine kinases (EGFR) inhibitors. 2D QSAR was performed
Malleshappa N. Noolvi, Harun M. Patel
doaj   +1 more source

An insight into the therapeutic potential of quinazoline derivatives as anticancer agents

, 2017
This article reviews the recent advances in the development of quinazoline derivatives as anticancer agents.
Irshad Ahmad, Shagufta Shagufta
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Novel quinazoline derivatives with biological activity [PDF]

Farmaceutická fakulta v Hradci Králové, Univerzita Karlova Katedra organické a bioorganické chemie Kandidát: Mgr. Zuzana Rania Brožová Školitel: prof. RNDr. Milan Pour, Ph.D.
Brožová, Zuzana Rania
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