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Protonation-Enhanced Reactivity of Triplet State in Dearomative Photocycloaddition of Quinolines to Olefins.

Organic Letters, 2021
The intermolecular dearomative cycloaddition of acidified bicyclic azaarenes with olefins was recently reported. We report here the crucial role of the acid in the dearomative photocycloaddition of quinolines to olefins.
Tatsuya Morofuji   +4 more
semanticscholar   +1 more source

Regiodivergent C-H Alkylation of Quinolines with Alkenes by Half-Sandwich Rare-Earth Catalysts.

Journal of the American Chemical Society, 2020
The regiodivergent catalysis of C-H alkylation with alkenes is of great interest and importance, but has remained hardly explored to date. We report herein the first regiodivergent C-H alkylation of quinolines with alkenes by half-sandwich rare-earth ...
Sha Lou   +6 more
semanticscholar   +1 more source

Quinolines

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
R. D. Larsen, D. Cai
openaire   +1 more source

Recent Advances on Diversity Oriented Heterocycle Synthesis of Fused Quinolines and Its Biological Evaluation

Polycyclic aromatic compounds (Print), 2020
During the last decade quinoline derivatives have been shown to be useful starting materials and building blocks for the synthesis of a great variety of functionalized polynuclear heterocyclic systems.
M. Abass   +3 more
semanticscholar   +1 more source

C3-H Trifluoroacetylation of Quinolines and Pyridines: Access to Heteroaryl Ketones, Carboxylic Acids, and Amides.

Organic Letters
Despite extensive synthetic endeavors, achieving direct C3-H trifluoroacetylation in quinolines/pyridines continues to pose significant challenges. We report a protocol for direct C3-H trifluoroacetylation of quinolines and pyridines under transition ...
Xu Wang   +5 more
semanticscholar   +1 more source

Dehydrogenative Synthesis of Quinolines, 2-Aminoquinolines, and Quinazolines Using Singlet Diradical Ni(II)-Catalysts.

Journal of Organic Chemistry, 2019
Simple, straightforward, and atom economic methods for the synthesis of quinolines, 2-aminoquinolines, and quinazolines via biomimetic dehydrogenative condensation/coupling reactions, catalyzed by well-defined inexpensive and easy to prepare singlet ...
G. Chakraborty   +6 more
semanticscholar   +1 more source

Metal-Ligand Cooperative Approach to Achieve Dehydrogenative Functionalization of Alcohols to Quinolines and Quinazolin-4(3H)-ones under Mild Aerobic Conditions.

Journal of Organic Chemistry, 2019
A simple metal-ligand cooperative approach for the dehydrogenative functionalization of alcohols to various substituted quinolines and quinazolin-4(3H)-ones under relatively mild reaction conditions (≤90°C) is reported.
Siuli Das   +6 more
semanticscholar   +1 more source

RuII-Catalyzed/NH2-Assisted Selective Alkenyl C-H [5 + 1] Annulation of Alkenylanilines with Sulfoxonium Ylides to Quinolines.

Organic Letters, 2019
A novel ruthenium-catalyzed [5 + 1] annulation of 2-alkenylanilines with sulfoxonium ylides was developed for the rapid assembly of highly functionalized quinolines.
Pu Chen   +4 more
semanticscholar   +1 more source

Quinoline-Based Antifungals

Current Medicinal Chemistry, 2010
Although the assortment of antifungal drugs is broad, the most commonly used agents have major drawbacks. Toxicity, serious side effects or the emergence of drug resistance are amongst them. New drugs and drug candidates under clinical trials do not guarantee better pharmacological parameters. These new medicines may appear effective; however; they may
R, Musiol   +3 more
openaire   +2 more sources

An Overview of Privileged Scaffold: Quinolines and Isoquinolines in Medicinal Chemistry as Anticancer Agents.

Current Topics in Medicinal Chemistry, 2020
Cancer is one of the most difficult diseases and causes of death for many decades. Many pieces of research are continuously going on to get a solution for cancer.
Yanna Mao   +3 more
semanticscholar   +1 more source

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