Narcolepsy: autoimmunity, effector T cell activation due to infection, or T cell independent, major histocompatibility complex class II induced neuronal loss? [PDF]
, 2017 Human narcolepsy with cataplexy is a neurological disorder, which develops due to a deficiency in hypocretin producing neurons in the hypothalamus. There is a strong association with human leucocyte antigens HLA-DR2 and HLA-DQB1*0602.
Bassetti, Claudio L. +5 more
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Serum Metabolomic Profiling of Piglets Infected with Virulent Classical Swine Fever Virus [PDF]
, 2017 Citation: Gong, W. J., Jia, J. J., Zhang, B. K., Mi, S. J., Zhang, L., Xie, X. M., . . . Tu, C. C. (2017). Serum Metabolomic Profiling of Piglets Infected with Virulent Classical Swine Fever Virus. Frontiers in Microbiology, 8, 14. doi:10.3389/fmicb.2017.
Bikai Zhang +10 more
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The excitotoxin quinolinic acid induces tau phosphorylation in human neurons.
PLoS ONE, 2009 Some of the tryptophan catabolites produced through the kynurenine pathway (KP), and more particularly the excitotoxin quinolinic acid (QA), are likely to play a role in the pathogenesis of Alzheimer's disease (AD).
Abdur Rahman +5 more
doaj +1 more source
Cell Transplantation, 2013 Huntington's disease (HD) produces severe neurodegeneration in the striatum leading to disabling motor impairments, including the loss of control of skilled reaching movements.
Alexander Klein +2 more
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Quinolinic acid metabolism in the rat brain. Immunohistochemical identification of 3-hydroxyanthranilic acid oxygenase and quinolinic acid phosphoribosyltransferase in the hippocampal region [PDF]
, 1988 C. Köhler +5 more
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Behavioral activation therapy for depression is associated with a reduction in the concentration of circulating quinolinic acid — Erratum [PDF]
, 2021 Jonathan Savitz +12 more
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Excitotoxic degeneration of hypothalamic orexin neurons in slice culture
Neurobiology of Disease, 2004 Several lines of evidence indicate that narcolepsy, a sleep disorder, results from the loss of hypothalamic orexin (hypocretin)-containing neurons, but the mechanisms responsible for selective elimination of this neuronal population are unknown.
Hiroshi Katsuki, Akinori Akaike
doaj +1 more source
Vitamin B, Relative Nutritive Value and Palatability of Germinated Com (Zea mays L.) 1 [PDF]
, 1979 Changes in the riboflavin, niacin, thiamin and Relative Nutritive Value (RNV) in germinated com were studied. The corn were germinated for four days at 30°C and then dried at 50°C and ground. The vitamins were analysed by microbiological methods. The RNV
Fields, Marion L., Hashim, Normah
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Effects of systemic and central nervous system localized inflammation on the contributions of metabolic precursors to the
, 2002 Tomoyuki Kita +3 more
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Quinolinic Acid In Vivo Synthesis Rates, Extracellular Concentrations, and Intercompartmental Distributions in Normal and Immune‐Activated Brain as Determined by Multiple‐Isotope Microdialysis [PDF]
, 1998 Karen E. Beagles +2 more
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