Results 131 to 140 of about 5,015,403 (283)

Conversion of 3-Hydroxyanthranilic Acid to Quinolinic Acid in Presence of Rat Liver treated with 2-Acetylaminofluorene [PDF]

, 1958
E Quagliariello, Sergio Auricchio, E Rinaldi   +2 more
openalex   +1 more source

Narcolepsy: autoimmunity, effector T cell activation due to infection, or T cell independent, major histocompatibility complex class II induced neuronal loss? [PDF]

, 2017
Human narcolepsy with cataplexy is a neurological disorder, which develops due to a deficiency in hypocretin producing neurons in the hypothalamus. There is a strong association with human leucocyte antigens HLA-DR2 and HLA-DQB1*0602.
Bassetti, Claudio L., Birchler, Thomas, Fontana, Adriano, Gast, Heidemarie, Recher, Mike, Reith, Walter   +5 more
core  

Quinolinic acid impairs mitophagy promoting microglia senescence and poor healthspan in C. elegans: a mechanism of impaired aging process. [PDF]

Biol Direct, 2023
Dongol A, Chen X, Zheng P, Seyhan ZB, Huang XF.   +4 more
europepmc   +1 more source

Reduced calcineurin protein levels and activity in exon-1 mouse models of Huntington's disease: Role in excitotoxicity

Neurobiology of Disease, 2009
Calcineurin is a serine/threonine phosphatase involved in the regulation of glutamate receptors signaling. Here, we analyzed whether the regulation of calcineurin protein levels and activity modulates the susceptibility of striatal neurons to ...
Xavier Xifró, Albert Giralt, Ana Saavedra, Juan M. García-Martínez, Miguel Díaz-Hernández, José J. Lucas, Jordi Alberch, Esther Pérez-Navarro   +7 more
doaj  

Systemic approaches to modifying quinolinic acid striatal lesions in rats [PDF]

, 1988
M. Flint Beal, N. W. Kowall, KJ Swartz, RJ Ferrante, Martin Jb   +4 more
openalex   +1 more source

Chronic quinolinic acid lesions in rats closely resemble Huntington's disease [PDF]

, 1991
M. F. Beal, RJ Ferrante, KJ Swartz, N. W. Kowall   +3 more
openalex   +1 more source

Cerebrospinal fluid quinolinic acid is strongly associated with delirium and mortality in hip-fracture patients. [PDF]

J Clin Invest, 2023
Watne LO, Pollmann CT, Neerland BE, Quist-Paulsen E, Halaas NB, Idland AV, Hassel B, Hassel B, Henjum K, Knapskog AB, Frihagen F, Raeder J, Godø A, Ueland PM, McCann A, Figved W, Selbæk G, Zetterberg H, Fang EF, Myrstad M, Giil LM.   +20 more
europepmc   +1 more source

De novo NAD+ synthesis is ineffective for NAD+ supply in axenically cultured Caenorhabditis elegans

Communications Biology
To secure an adequate nicotinamide adenine dinucleotide (NAD+) supply for survival, organisms typically rely on two complementary mechanisms: the de novo synthesis pathway and the salvage pathway.
Shihao Zhu, Runshuai Zhang, Luxia Yao, Zhirong Lin, Yanjie Li, Siyuan Li, Lianfeng Wu   +6 more
doaj   +1 more source

CSF neopterin, quinolinic acid and kynurenine/tryptophan ratio are biomarkers of active neuroinflammationResearch in context

EBioMedicine, 2023
Summary: Background: Defining the presence of acute and chronic brain inflammation remains a challenge to clinicians due to the heterogeneity of clinical presentations and aetiologies.
Jingya Yan, Kavitha Kothur, Shekeeb Mohammad, Jason Chung, Shrujna Patel, Hannah F. Jones, Brooke A. Keating, Velda X. Han, Richard Webster, Simone Ardern-Holmes, Jayne Antony, Manoj P. Menezes, Esther Tantsis, Deepak Gill, Sachin Gupta, Tejaswi Kandula, Hugo Sampaio, Michelle A. Farrar, Christopher Troedson, P Ian Andrews, Sekhar C. Pillai, Benjamin Heng, Gilles J. Guillemin, Anna Guller, Sushil Bandodkar, Russell C. Dale   +25 more
doaj  

Vitamin B, Relative Nutritive Value and Palatability of Germinated Com (Zea mays L.) 1 [PDF]

, 1979
Changes in the riboflavin, niacin, thiamin and Relative Nutritive Value (RNV) in germinated com were studied. The corn were germinated for four days at 30°C and then dried at 50°C and ground. The vitamins were analysed by microbiological methods. The RNV
Fields, Marion L., Hashim, Normah
core