Metabolic engineering of Escherichia coli for quinolinic acid production by assembling L-aspartate oxidase and quinolinate synthase as an enzyme complex. [PDF]
Zhu F, Peña M, Bennett GN.
europepmc +1 more source
Enhanced neuronal damage by co‐administration of quinolinic acid and free radicals, and protection by adenosine A2A receptor antagonists [PDF]
W. M. H. Behan, Trevor W. Stone
openalex +1 more source
Mechanistic Insight into Diosmin-Induced Neuroprotection and Memory Improvement in Intracerebroventricular-Quinolinic Acid Rat Model: Resurrection of Mitochondrial Functions and Antioxidants. [PDF]
Huang M+5 more
europepmc +1 more source
Quinolinic acid, a kynurenine/tryptophan pathway metabolite, associates with impaired cognitive test performance in systemic lupus erythematosus. [PDF]
Anderson EW+8 more
europepmc +1 more source
A short review on toxin-induced animal models of Huntington’s disease
BACKGROUND: Huntington's disease (HD) is a hereditary neurodegenerative motor and cognitive disorder. Different animal models of HD have been provided to study the different aspects of the disease, such as pathophysiology and treatment, and also the cure.
Ahmad Fotoohi
doaj +1 more source
Increased Indoleamine-2,3-Dioxygenase Activity Is Associated With Poor Clinical Outcome in Adults Hospitalized With Influenza in the INSIGHT FLU003Plus Study [PDF]
BACKGROUND: Indoleamine-2,3-dioxygenase (IDO) mediated tryptophan (TRP) depletion has antimicrobial and immuno-regulatory effects. Increased kynurenine (KYN)-to-TRP (KT) ratios, reflecting increased IDO activity, have been associated with poorer outcomes
Davey, RT+12 more
core
Positive association between serum quinolinic acid and functional connectivity following concussion. [PDF]
Meier TB+7 more
europepmc +1 more source
CSF quinolinic acid levels are determined by local HIV infection: cross-sectional analysis and modelling of dynamics following antiretroviral therapy [PDF]
Marta Valle+4 more
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Evaluation of intracellular processes in quinolinic acid-induced brain damage by imaging reactive oxygen species generation and mitochondrial complex I activity. [PDF]
Hosoi R+10 more
europepmc +1 more source