Results 51 to 60 of about 880,028 (202)
, 2014 Correction: Specific Reactions of Different Striatal Neuron Types in Morphology Induced by Quinolinic Acid in ...
PLOS ONE (2189197)
core +1 more source
Marine DrugsDepression is increasingly linked to microbiota–gut–brain axis dysfunction, yet current monoaminergic antidepressants show limited efficacy. This study investigated the therapeutic potential and underlying mechanisms of GV-971, a marine-derived ...
Zhuandi He +8 more
doaj +1 more source
Clinical and Translational Medicine, Volume 16, Issue 11, November 2026.This Review proposes a microbiome–premetastatic brain niche axis connecting gut, lung, and intratumoral microbes with metabolites, blood–brain barrier remodeling, neuroimmune priming, and brain metastasis in NSCLC. It integrates current evidence while distinguishing established mechanisms from associations and hypotheses requiring prospective and ...
Long Liang +8 more
wiley +1 more source
Estudo dos mecanismos envolvidos no efeito neuroprotetor do pré-condicionamento com N-Metil-D-Aspartato (NMDA) [PDF]
, 2014 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Neurociências, Florianópolis, 2014.O pré-condicionamento cerebral é caracterizado por um estado de tolerância transitória do tecido ...
Constantino, Leandra Celso
core
, 2015 The tryptophan metabolite, quinolinic (2,3-pyridinedicarboxylic) acid, is known as an endogenous neurotoxin. Quinolinic acid can form coordination complexes with iron or copper.
Weckwerth, Wolfram +3 more
core +1 more source
How the gut microbiome affects the immunotherapy response in hepatocellular carcinoma
Cancer Biology & MedicineHepatocellular carcinoma (HCC) remains a major global health challenge with limited long-term survival despite advances in surgical, locoregional, and systemic treatments.
Mengrui Wu, Yating Zhang, Jun Yu
doaj +1 more source
MedComm, Volume 7, Issue 11, November 2026.Efferocytosis is a key process for macrophages to clear apoptotic cells, which undergoes the “ Find Me” chemotaxis signal stage, the “eat me” phagocytosis recognition stage and the “digest me” digestion stage in turn. During the aforementioned three stages, various signaling molecules released by apoptotic cells can promote the phenotypic polarization ...
Qiuping Chen +3 more
wiley +1 more source
Human brain matters: Navigating the neuropathology of COVID‐19
Brain Pathology, Volume 36, Issue 6, November 2026.Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland +4 more
wiley +1 more source
Estudo das Vias de Sinalização Envolvidas no Pré-condicionamento com N-Metil-D-Aspartato (NMDA) sobre Convulsões Induzidas por Ácido Quinolínico em Camundongos [PDF]
, 2008 TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.O pré-condicionamento cerebral se refere a um estado de tolerância transitória do tecido nervoso a um estimulo letal evocado por um insulto moderado prévio ...
Herculano, Bruno
core
The FASEB Journal, Volume 40, Issue 20, 31 October 2026.A single exercise session transiently modulates systemic kynurenine pathway metabolism. Immediately after exercise, tryptophan decreases while kynurenine, KYN/TRP, kynurenic acid, and quinolinic acid increase. During recovery, lower tryptophan, higher KYN/TRP, and kynurenic acid remain.
Marcus Vinicius dos Santos Rangel +7 more
wiley +1 more source