Results 101 to 110 of about 24,157 (222)
Studies in Benzimidazo Thiazolo Quinoxalines and Benzimidazo Thiazino Quinoxalines
Benzimidazo (2', 1': 2, 3) thiazolo (4, 5-b) quinoxalines and 7H-benzimidazo (1', 2': 4, 5) (1 : 4) thiazino (2, 3-b) quinoxalines have been synthesised by the condensations of 2-mercapto benzimidazoles with 2 : 3-dichloro quinoxalines and 2-(mercaptomethyl) benzimidazole with 2 : 3-dichloro quinoxalines respectively.
Simran Singh +2 more
openaire +1 more source
Bay‐functionalized [7]Helicene Bilayer Nanographenes
Bay‐functionalized [7]helical bilayer nanographenes are synthesized via a scalable, modular strategy enabling late‐stage diversification. Tailored methoxy, diketone, and phenazine substitutions precisely tune redox, photophysical, and chiroptical properties, delivering strong electronic circular dichroism and bright circularly polarized luminescence ...
Anmol Thanai +9 more
wiley +1 more source
rac-(2R,3S)-2-Phenyl-3-(3-phenyl-1,2,3,4-tetrahydroquinoxalin-2-yl)quinoxaline
The title compound, C28H22N4, is the unexpected by-product of the reaction of 2-hydroxyacetophenone and 1,2-diaminobenzene under iodine catalysis, during which a carbon–carbon σ-bond between two quinoxaline units was formed.
Sven Ammermann +4 more
doaj +1 more source
Divergent Access to Fluorinated Pharmacons From Ethyl Trifluoropyruvate
Fluoro(oxo) functional group diversification is traditionally accomplished through either specialized reagents or nucleophilic trifluoromethylation. Herein is disclosed the use of commercially available building blocks for the synthesis of trifluoromethyl(hydroxy) esters.
Rifat N. Nabi +4 more
wiley +1 more source
Synthesis of new derivants 11h-indeno[1,2-b] - quinoxaline as perspective inhibitors of JNK (C-Jun n-terminalnal kinase) [PDF]
Various quinoxalines show biological activity and have such properties as antiviral, antibacterial, antimicrobial, anti-inflammatory, anticancer, antidepressant, vermicidal, and act as inhibitors of kinases [1].
Barry, Jean-Cyriaque +2 more
core +1 more source
A dioxolanyl linchpin has been used to synthesize aryl ethanolamines from readily available aryl bromide and amine starting materials using a metallaphotoredox/substitution telescoped sequence. This combinatorial approach allows for a wide synthetic scope of both heteroarenes and cyclic amines. Aryl ethanolamines are an important functional group found
Justin J. Chang +4 more
wiley +1 more source
One-pot three-component coupling of o-alkynylheteroaryl carbonyl derivatives with Fischer carbene complexes and dienophiles leading to the synthesis of quinoxaline and phenazine ring systems has been investigated. This involves the generation of furo[3,4-
Priyabrata Roy, Binay Krishna Ghorai
doaj +1 more source
A universal ROR1 antibody‐engineered lipid nanoparticle (LNP) is constructed by sequential drug encapsulation and antibody conjugation. The LNP not only enables enhanced chemotherapeutic efficiency by targeting drug delivery and precise localization of deep‐seated tumors through NIR‐II fluorescence imaging, but also remodels immunosuppressive TME ...
Yeneng Dai +12 more
wiley +1 more source
Synthesis and biological evaluation of new quinoxaline derivatives as antioxidant and anti-inflammatory agents [PDF]
We report the synthesis, anti-inflammatory and antioxidant activities of novel quinoxaline and quinoxaline 1,4-di-N-oxide derivatives. Microwave assisted methods have been used in order to optimize reaction times and to improve the yields.
Aldana, I. (Ignacio) +10 more
core +1 more source
Quinoxalines are a group of antibiotics widely used in medicine to fight bacterial infections.These antibiotics have a broad spectrum of action and belong to the class of 4 quinolones. Theirmechanism of action is based on inhibiting the activity of bacterial enzymes responsible for DNAsynthesis, which leads to their death. Due to this, quinoxalines are
openaire +1 more source

