Results 1 to 10 of about 9,953 (212)

Quinoxaline derivatives as attractive electron-transporting materials. [PDF]

Beilstein J Org Chem, 2023
This review article provides a comprehensive overview of recent advancements in electron transport materials derived from quinoxaline, along with their applications in various electronic devices. We focus on their utilization in organic solar cells (OSCs), dye-sensitized solar cells (DSSCs), organic field-effect transistors (OFETs), organic-light ...
Abid Z, Ali L, Gulzar S, Wahad F, Ashraf RS, Nielsen CB.   +5 more
europepmc   +5 more sources

Quinoxaline Derivatives as Antiviral Agents: A Systematic Review. [PDF]

Molecules, 2020
Background: In recent decades, several viruses have jumped from animals to humans, triggering sizable outbreaks. The current unprecedent outbreak SARS-COV-2 is prompting a search for new cost-effective therapies to combat this deadly pathogen. Suitably functionalized polysubstituted quinoxalines show very interesting biological properties (antiviral ...
Montana M, Montero V, Khoumeri O, Vanelle P.   +3 more
europepmc   +6 more sources

Synthesis and hypoglycemic activity of quinoxaline derivatives. [PDF]

Front Chem, 2023
In this study, a new series of quinoxalinone derivatives (5a–5p, 6a–6n) was designed and its hypoglycemic activity was evaluated. The results showed that compounds 5i and 6b exhibited stronger hypoglycemic effects than the lead compounds and were comparable to the positive control Pioglitazone.
Jia W, Wang J, Wei C, Bian M, Bao S, Yu L.   +5 more
europepmc   +4 more sources

Synthesis of quinoxaline 1,4-di-N-oxide derivatives on solid support using room temperature and microwave-assisted solvent-free procedures [PDF]

Química Nova, 2011
We describe the synthesis of 12 new ethyl and methyl quinoxaline-7-carboxylate 1,4-di-N-oxide derivatives on solid supports with room temperature and microwave-assisted solvent-free procedures.
Bocanegra-Garcia, V. (Virgilio), Gomez-Caro, L.C. (Lilia C.), Monge, A. (Antonio), Rivera, G. (Gildardo), Sanchez-Sanchez, M. (Mario)   +4 more
core   +3 more sources

Synthesis, In Vitro Antiproliferative Activity, and In Silico Evaluation of Novel Oxiranyl-Quinoxaline Derivatives. [PDF]

Pharmaceuticals (Basel), 2022
The quinoxaline core is a promising scaffold in medicinal chemistry. Multiple quinoxaline derivatives, such as the topoisomerase IIβ inhibitor XK-469 and the tissue transglutaminase 2 inhibitor GK-13, have been evaluated for their antiproliferative ...
Montero V, Montana M, Khoumeri O, Correard F, Estève MA, Vanelle P.   +5 more
europepmc   +2 more sources

Synthesis, molecular modelling, and biological evaluation of novel quinoxaline derivatives for treating type II diabetes. [PDF]

J Enzyme Inhib Med Chem
Quinoxalines are benzopyrazine derivatives with significant therapeutic impact in the pharmaceutical industry. They proved to be useful against inflammation, bacterial, fungal, viral infection, diabetes and other applications.
Alasmary FAS, Abdullah DA, Masand VH, Ben Bacha A, Omar Ebeid AM, El-Araby ME, Alafeefy AM.   +6 more
europepmc   +2 more sources

Synthesis of novel antibacterial and antifungal quinoxaline derivatives. [PDF]

RSC Adv, 2022
Structure of some commercial agents.
Tang X, Zhou Q, Zhan W, Hu D, Zhou R, Sun N, Chen S, Wu W, Xue W.   +8 more
europepmc   +4 more sources

A High-Throughput Screening Method for Determining the Optimized Synthesis Conditions of Quinoxaline Derivatives Using Microdroplet Reaction. [PDF]

Front Chem, 2020
Quinoxaline derivatives demonstrate many distinguished chemical, biological, and physical properties and have a wide application in dyes, electroluminescent material, organic semiconductors, biological agents, etc.
Yang Y, Liu J, Chen Z, Niu W, Li R, Niu L, Yang P, Mu X, Tang B.   +8 more
europepmc   +2 more sources

Eco-friendly approach to access of quinoxaline derivatives using nanostructured pyrophosphate Na₂PdP₂O₇ as a new, efficient and reusable heterogeneous catalyst. [PDF]

BMC Chem, 2020
In the present study, we report the synthesis of various quinoxaline derivatives from direct condensation of substituted aromatic 1,2-diamine with 1,2-dicarbonyl catalyzed by nanostructured pyrophosphate Na2PdP2O7 as a new highly efficient ...
Dânoun K, Essamlali Y, Amadine O, Mahi H, Zahouily M.   +4 more
europepmc   +2 more sources

Synthesis, Biological Evaluation, and In Silico Studies of New Acetylcholinesterase Inhibitors Based on Quinoxaline Scaffold

Molecules, 2021
A quinoxaline scaffold exhibits various bioactivities in pharmacotherapeutic interests. In this research, twelve quinoxaline derivatives were synthesized and evaluated as new acetylcholinesterase inhibitors.
Paptawan Suwanhom, Jirakrit Saetang, Pasarat Khongkow, Teerapat Nualnoi, Varomyalin Tipmanee, Luelak Lomlim   +5 more
doaj   +1 more source