Results 21 to 30 of about 9,953 (212)

An alternative method to access diverse N,N′-diquaternised-3,3′-biquinoxalinium “biquinoxen” dications [PDF]

, 2017
An alternative synthetic route for the design of N,N′-diquaternised-3,3′-biquinoxalinium “biquinoxen” dications is reported, involving oxidative radical coupling of dithionite reduced quinoxaline quaternary salts.
Leblanc, Nicolas, Powell, Annie K., Sproules, Stephen   +2 more
core   +1 more source

Density Functional Theory and Quantitative Structure-Activity Relationship Studies of some Quinoxaline derivatives as potential Corrosion Inhibitors for Copper in Acidic Medium

International Journal of Electrochemical Science, 2012
Density Functional Theory (DFT) using the B3LYP functional and Quantitative Structure-Activity Relationship QSAR studies is reported on some quinoxaline derivatives namely 3-methyl-2-phenyl quinoxaline (MPQ), 2,3-diphenyl quinoxaline (PPQ), 3-methyl-2(2 ...
Mwadham M. Kabanda, Eno E. Ebenso
doaj   +1 more source

DISCOVERY OF TRIKETONE-QUINOXALINE HYBRIDS AS POTENT HPPD INHIBITORS USING STRUCTURE-BASED DRUG DESIGN [PDF]

Frontiers of Agricultural Science and Engineering, 2022
<List> <ListItem><ItemContent><p>• HPPD is one of the most promising targets for new herbicides.</p></ItemContent></ListItem> <ListItem><ItemContent><p>• A family of novel HPPD ...
Baifeng ZHENG, Yaochao YAN, Can FU, Guangyi HUANG, Long ZHAO, Qiong CHEN, Renyu QU, Guangfu YANG
doaj   +1 more source

Microwave assisted synthesis of quinoxaline derivatives

Results in Chemistry, 2023
Substituted quinoxalines are known building blocks for compounds with pharmacological, agricultural, and material uses. Forming carbon-heteroatom bonds at the 2,3-positions on quinoxaline can be challenging. 2,3-chloroquinoxaline can undergo nucleophilic aromatic substitution however it must be in the presence of metal catalysts.
Lucas K. Beagle, Eric Horsting, Jacob Buechele, Judit K. Beagle   +3 more
openaire   +2 more sources

Novel Synthetic Routes to Prepare Biologically Active Quinoxalines and Their Derivatives: A Synthetic Review for the Last Two Decades

Molecules, 2021
Quinoxalines, a class of N-heterocyclic compounds, are important biological agents, and a significant amount of research activity has been directed towards this class.
Hena Khatoon, Emilia Abdulmalek
doaj   +1 more source

Sinteza, in vitro antitumorsko ispitivanje i radiosenzitirajuće vrednovanje novih derivata 4-[3-(supstituiranih)tioureido]-N-(kinoksalin-2-il)benzensulfonamida [PDF]

, 2011
Sulfonamides and quinoxaline derivatives possess many types of biological activities and have been recently reported to show substantial antitumor activity. This paper reports the synthesis of novel thioureidosulfaquinoxaline derivatives.
A. Budakoti, A. Carta, F. Mohamadi, Fatma Ragab, G. Rush, Helmy Heiba, J. Fisherman, M. El-Gaby, M. Fisher, M. Ghorab, M. Ghorab, M. Ghorab, Marwa El-Gazzar, Mostafa El-Gazzar, Mostafa Ghorab, P. Skehan, R. Giri, S. Sehlstedt, V. Tandon, Y. Nishimura   +19 more
core   +2 more sources

Synthesis and biological evaluation of novel substituted pyrrolo[1,2-a]quinoxaline derivatives as inhibitors of the human protein kinase CK2 [PDF]

, 2013
Herein we describe the synthesis and properties of substituted phenylaminopyrrolo[1,2-a]quinoxaline-carboxylic acid derivatives as a novel class of potent inhibitors of the human protein kinase CK2.
Alvarez, Lautaro Damian, Baratin, Sophie, Bollacke, Andre, Desplat, Vanessa, Guillon, Jean, Joachim, Jose, Le Borgne, Marc, Marchivie, Mathieu, Moreau, Stéphane, Pecci, Adali, Pinaud, Noël, Rimbault, Charlotte, Roche, Séverine, Savrimoutou, Solène   +13 more
core   +4 more sources

Substitutions of fluorine atoms and phenoxy groups in the synthesis of quinoxaline 1,4-di-N-oxide derivatives. [PDF]

, 2008
The unexpected substitution of fluorine atoms and phenoxy groups attached to quinoxaline or benzofuroxan rings is described. The synthesis of 2-benzyl- and 2-phenoxy- 3-methylquinoxaline 1,4-di-N-oxide derivatives was based on the classical Beirut ...
Aldana, I. (Ignacio), Ancizu, S. (Saioa), Burguete, A. (Asunción), Monge, A. (Antonio), Pérez-Silanes, S. (Silvia), Solano, B. (Beatriz), Vicente, E. (Esther), Villar, R. (Raquel)   +7 more
core   +2 more sources

Synthesis, Biological Evaluation and Structure-Activity Relationships of New Quinoxaline Derivatives as Anti-Plasmodium falciparum Agents

Molecules, 2014
We report the synthesis and antimalarial activities of eighteen quinoxaline and quinoxaline 1,4-di-N-oxide derivatives, eight of which are completely novel. Compounds 1a and 2a were the most active against Plasmodium falciparum strains.
Ana Gil, Adriana Pabón, Silvia Galiano, Asunción Burguete, Silvia Pérez-Silanes, Eric Deharo, Antonio Monge, Ignacio Aldana   +7 more
doaj   +1 more source

1,4-Di-N-oxide quinoxaline-2-carboxamide: Cyclic voltammetry and relationship between electrochemical behavior, structure and anti-tuberculosis activity [PDF]

, 2011
To gain insight into the mechanism of action, the redox properties of 37 quinoxaline-2-carboxamide 1,4-di-N-oxides with varying degrees of anti-tuberculosis activity were studied in dimethylformamide (DMF) using cyclic voltammetry and first derivative ...
Aldana, I. (Ignacio), Ancizu, S. (Saioa), Crawford, P.W. (Philip W.), Gouravaram, S. (S.), Macharam, A. (Abinav), Monge, A. (Antonio), Moreno-de-Viguri, E. (Elsa), Pérez-Silanes, S. (Silvia), Torres, E. (Enrique)   +8 more
core   +1 more source