International audienceAmmonium bifluoride was efficiently used (at a 0.5 mol % loading) to catalyze the cyclocondensation between 1,2-arylenediamines and 1,2-dicarbonyl compounds at room temperature in methanol-water, affording quinoxalines and pyrido[2 ...
Chevallier, Floris +5 more
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Chemistry and pharmacological diversity of quinoxaline motifs as anticancer agents
Surpassing heart diseases, cancer is taking the lead as the deadliest disease because of its fast rate of spreading in all parts of the world. Tireless commitment to searching for novel therapeutic medicines is a worthwhile adventure in synthetic ...
Ajani Olayinka O. +5 more
doaj +1 more source
Antioxidant Activity and Oxidation Products of 1,2,3,4- Tetrahydroquinoxalines in Peroxyl Radical Scavenging Reactions, Part I [PDF]
This paper studies the antioxidant activity of 1,2,3,4-tetrahydroquinolines, 3,4-dihydro-2H-benzo[1,4]thiazines and 1,2,3,4-tetrahydroquinoxalines in the inhibition of the peroxidation of tetralin induced by an azo initiator.
Nishiyama Tomohiro +5 more
core +1 more source
New quinoxaline derivatives as potential MT₁ and MT₂ receptor ligands. [PDF]
Ever since the idea arose that melatonin might promote sleep and resynchronize circadian rhythms, many research groups have centered their efforts on obtaining new melatonin receptor ligands whose pharmacophores include an aliphatic chain of variable ...
Aldana, I. (Ignacio) +7 more
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Quinoxaline derivatives have garnered significant attention due to their wide-ranging therapeutic applications. Research from 2020 to 2024 has demonstrated their potent bioactivity across various domains, including anticancer, antimicrobial, antiviral ...
Aly M. Waseem +9 more
doaj +1 more source
Ionic liquid 1-butyl-3-methylimidazolium bromide ([bmim]Br): a green and neutral reaction media for the efficient, catalyst-free synthesis of quinoxaline derivatives [PDF]
Quinoxaline derivatives were produced in excellent yields and short reaction times via the condensation of 1,2-diamines with 1,2-diketones in the neutral ionic liquid 1-butyl-3-methylimidazolium bromide ([bmim]Br) under catalyst-free and microwave ...
MAASOOMEH KHEDRI +9 more
doaj
Antimicrobial resistance remains a global issue, hindering the control of bacterial infections. This study examined the antimicrobial properties of 2,3‐N,N‐diphenyl quinoxaline derivatives against Gram‐positive, Gram‐negative, and Mycobacterium species ...
Gilda Padalino +5 more
doaj +1 more source
Helical Airflow Synthesis of Quinoxalines: A Continuous and Efficient Mechanochemical Approach
In this work, we report a novel mechanochemical synthesis method for the synthesis of quinoxaline derivatives—a spiral gas–solid two-phase flow approach, which enables the efficient preparation of quinoxaline compounds. Compared to conventional synthetic
Jiawei Zhang +5 more
doaj +1 more source
In situ polymerization of monomers for polyphenylquinoxaline-graphite fiber composites [PDF]
In situ polymerization of monomers was used to prepare graphite-fiber-reinforced polyphenylquinoxaline composites. Six different monomer combinations were investigated. Composite mechanical property retention characteristics were determined at 316 C (600
Delvigs, P. +2 more
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Effect Of Cooking Methods And Conditions On Heterocyclic Amines Content In Satay And Roasted Marinated Chicken [PDF]
The objectives of this study were to determine the effect of cooking method on HAs concentration of chicken and beef satay and the effect of marinating and different cooking conditions on HAs concentration of roasted chicken.
Mohd Mukhtar, Mohd Safzan
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