Results 81 to 90 of about 29,062 (270)
Quinoxaline: A comprehension of current pharmacological advancement in medicinal chemistry
Quinoxaline is a fused heterocycle ring template present in diverse pharmacophore and widely used in medicinal chemistry. Owing to its vast pharmaceutical profile, several quinoxalines analogous displayed their distinct pharmacological activities. In the
Suresh Kumar Suthar+4 more
doaj
rac-(2R,3S)-2-Phenyl-3-(3-phenyl-1,2,3,4-tetrahydroquinoxalin-2-yl)quinoxaline
The title compound, C28H22N4, is the unexpected by-product of the reaction of 2-hydroxyacetophenone and 1,2-diaminobenzene under iodine catalysis, during which a carbon–carbon σ-bond between two quinoxaline units was formed.
Sven Ammermann+4 more
doaj +1 more source
FGF-2 Induces Neuronal Death through Upregulation of System xc- [PDF]
The cystine/glutamate antiporter (system xc-) transports cystine into cell in exchange for glutamate. Fibroblast growth factor-2 (FGF-2) upregulates system xc- selectively on astrocytes, which leads to increased cystine uptake, the substrate for ...
Albano, Rebecca+2 more
core +1 more source
Polycyclic Aromatics as Promising Phosphorescence Materials
This review focuses on the recent progress of polycyclic aromatic compounds (PACs)‐based phosphorescent materials. Their molecular structural characteristics as promising phosphors are highlighted, and the efficient strategies from molecular and aggregation levels have been illustrated systematically to promote the development of PACs with desirable ...
Peipei Liu, Qianqian Li, Zhen Li
wiley +1 more source
A series of novel isolated β-lactams 3a-c and thiazolidinone derivatives 4a-c were successfully synthesized from reactions of new Schiff's bases 2a-c with chloroacetyl chloride and thioglycolic acid.
Hajer Hrichi+2 more
doaj +1 more source
Perampanel inhibition of AMPA receptor currents in cultured hippocampal neurons. [PDF]
Perampanel is an aryl substituted 2-pyridone AMPA receptor antagonist that was recently approved as a treatment for epilepsy. The drug potently inhibits AMPA receptor responses but the mode of block has not been characterized.
Chen, Chao-Yin+3 more
core +3 more sources
A novel family of water‐soluble, nontoxic, and phosphorescent N‐glycosylated Ru(II) phenanthroline‐based complexes are reported. They exhibit photoselectivity indexes ranging from 10 to 44 in PC‐3 cells, while impacting cell migration and resistance to detachment after irradiation with blue light.
Elena de la Torre‐Rubio+5 more
wiley +1 more source
Ionization effects on the partitioning behavior of food and beverage aroma compounds between aqueous phases and air and organic matrices [PDF]
Aroma compounds in the Flavornet database were screened for ionizable functional groups such as carboxylic acids, aliphatic and aromatic amines, phenols, alcohols, and thiols.
Kaya Forest, Sierra Rayne
core +2 more sources
Organic Interlayer for Enhanced Buried Interfaces in Wide‐Bandgap Perovskite Solar Cells
High‐performance, stable wide‐bandgap perovskite solar cells (PSCs) are vital for tandem cell development, yet nonradiative interfacial recombination limits efficiency. Herein, a donor–acceptor quinoxaline‐based interlayer is introduced (QxNN) at the NiOx/perovskite interface in p‐i‐n PSCs. This interlayer passivates defects, enhances charge extraction
JeeHee Hong+5 more
wiley +1 more source
Quinoxaline 1,4-di-N-oxide and the Potential for Treating Tuberculosis [PDF]
New drugs active against drug-resistant tuberculosis are urgently needed to extend the range of TB treatment options to cover drug resistant infections.
Aldana, I. (Ignacio)+11 more
core