Results 81 to 90 of about 29,062 (270)

Quinoxaline: A comprehension of current pharmacological advancement in medicinal chemistry

open access: yesEuropean Journal of Medicinal Chemistry Reports, 2022
Quinoxaline is a fused heterocycle ring template present in diverse pharmacophore and widely used in medicinal chemistry. Owing to its vast pharmaceutical profile, several quinoxalines analogous displayed their distinct pharmacological activities. In the
Suresh Kumar Suthar   +4 more
doaj  

rac-(2R,3S)-2-Phenyl-3-(3-phenyl-1,2,3,4-tetrahydroquinoxalin-2-yl)quinoxaline

open access: yesActa Crystallographica Section E, 2008
The title compound, C28H22N4, is the unexpected by-product of the reaction of 2-hydroxyacetophenone and 1,2-diaminobenzene under iodine catalysis, during which a carbon–carbon σ-bond between two quinoxaline units was formed.
Sven Ammermann   +4 more
doaj   +1 more source

FGF-2 Induces Neuronal Death through Upregulation of System xc- [PDF]

open access: yes, 2014
The cystine/glutamate antiporter (system xc-) transports cystine into cell in exchange for glutamate. Fibroblast growth factor-2 (FGF-2) upregulates system xc- selectively on astrocytes, which leads to increased cystine uptake, the substrate for ...
Albano, Rebecca   +2 more
core   +1 more source

Polycyclic Aromatics as Promising Phosphorescence Materials

open access: yesChemistryEurope, EarlyView.
This review focuses on the recent progress of polycyclic aromatic compounds (PACs)‐based phosphorescent materials. Their molecular structural characteristics as promising phosphors are highlighted, and the efficient strategies from molecular and aggregation levels have been illustrated systematically to promote the development of PACs with desirable ...
Peipei Liu, Qianqian Li, Zhen Li
wiley   +1 more source

Novel Β-lactams and Thiazolidinone Derivatives from 1,4-dihydroquinoxaline Schiff’s Base: Synthesis, Antimicrobial Activity and Molecular Docking Studies

open access: yesChemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2020
A series of novel isolated β-lactams 3a-c and thiazolidinone derivatives 4a-c were successfully synthesized from reactions of new Schiff's bases 2a-c with chloroacetyl chloride and thioglycolic acid.
Hajer Hrichi   +2 more
doaj   +1 more source

Perampanel inhibition of AMPA receptor currents in cultured hippocampal neurons. [PDF]

open access: yes, 2014
Perampanel is an aryl substituted 2-pyridone AMPA receptor antagonist that was recently approved as a treatment for epilepsy. The drug potently inhibits AMPA receptor responses but the mode of block has not been characterized.
Chen, Chao-Yin   +3 more
core   +3 more sources

Exploring the Impact of Phenanthroline‐Based Glycoconjugated Ru(II) Polypyridyl Photosensitizers on Metastasis‐Related Processes

open access: yesChemistry – A European Journal, EarlyView.
A novel family of water‐soluble, nontoxic, and phosphorescent N‐glycosylated Ru(II) phenanthroline‐based complexes are reported. They exhibit photoselectivity indexes ranging from 10 to 44 in PC‐3 cells, while impacting cell migration and resistance to detachment after irradiation with blue light.
Elena de la Torre‐Rubio   +5 more
wiley   +1 more source

Ionization effects on the partitioning behavior of food and beverage aroma compounds between aqueous phases and air and organic matrices [PDF]

open access: yes, 2011
Aroma compounds in the Flavornet database were screened for ionizable functional groups such as carboxylic acids, aliphatic and aromatic amines, phenols, alcohols, and thiols.
Kaya Forest, Sierra Rayne
core   +2 more sources

Organic Interlayer for Enhanced Buried Interfaces in Wide‐Bandgap Perovskite Solar Cells

open access: yesChemSusChem, EarlyView.
High‐performance, stable wide‐bandgap perovskite solar cells (PSCs) are vital for tandem cell development, yet nonradiative interfacial recombination limits efficiency. Herein, a donor–acceptor quinoxaline‐based interlayer is introduced (QxNN) at the NiOx/perovskite interface in p‐i‐n PSCs. This interlayer passivates defects, enhances charge extraction
JeeHee Hong   +5 more
wiley   +1 more source

Quinoxaline 1,4-di-N-oxide and the Potential for Treating Tuberculosis [PDF]

open access: yes, 2011
New drugs active against drug-resistant tuberculosis are urgently needed to extend the range of TB treatment options to cover drug resistant infections.
Aldana, I. (Ignacio)   +11 more
core  

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