Results 51 to 60 of about 9,953 (212)

Substrate‐Affinitive P‐Type Azapolycyclic Photosensitizer for Chemoselective Nitrilization Under Mild Conditions

Advanced Science, EarlyView.
We developed a series of quinoxalinoquinoxaline (QQ) photosensitizers featuring high and tunable excited‐state reduction potentials (E(PC•+/PC*) = –1.76 to –2.05 V vs. SCE). Their hydrogen‐bonding interaction with carbonyl substrates enables selective single‐electron transfer events for selective nitrilization of 1° amides, offering a tunable ...
Seongwoo Bae, Dongwook Kim, Jinwoo Kim
wiley   +1 more source

Synthetic strategies for 5- and 6-membered ring azaheterocycles facilitated by iminyl radicals [PDF]

, 2016
The author thanks EaStCHEM for financial support.The totality of chemical space is so immense that only a small fraction can ever be explored. Computational searching has indicated that bioactivity is associated with a comparatively small number of ring ...
Walton, John Christopher
core   +2 more sources

Crystal structure of ethyl (2S,2′ R)-1′-benzyl-3-oxo-3H-dispiro[1-benzothio-phene-2,3′-pyrrolidine-2′,11″-indeno-[1,2-b]quinoxaline]-4′-carboxylate [PDF]

, 2015
The authors thank the TBI X-ray facility, CAS in Crystallography and BioPhysics, University of Madras, Chennai, India, for the data collection.Peer reviewedPublisher ...
Govindaraj, J., Raghunathan, R., Raja, R, SubbiahPandi, A., Suresh, M   +4 more
core   +2 more sources

Novel Derivatives of Quinoxaline-2-carboxylic Acid 1,4-Dioxides as Antimycobacterial Agents: Mechanistic Studies and Therapeutic Potential

Pharmaceuticals, 2023
The World Health Organization (WHO) reports that tuberculosis (TB) is one of the top 10 leading causes of global mortality. The increasing incidence of multidrug-resistant TB highlights the urgent need for an intensified quest to discover innovative anti-
Svetlana G. Frolova, Aleksey A. Vatlin, Dmitry A. Maslov, Buhari Yusuf, Galina I. Buravchenko, Olga B. Bekker, Ksenia M. Klimina, Svetlana V. Smirnova, Lidia M. Shnakhova, Irina K. Malyants, Arseniy I. Lashkin, Xirong Tian, Md Shah Alam, George V. Zatonsky, Tianyu Zhang, Andrey E. Shchekotikhin, Valery N. Danilenko   +16 more
doaj   +1 more source

Quinoxaline derivatives as new inhibitors of coxsackievirus B5 [PDF]

European Journal of Medicinal Chemistry, 2018
Enteroviruses are among the most common and important human pathogens for which there are no specific antiviral agents approved by the US Food and Drug Administration so far. Particularly, coxsackievirus infections have a worldwide distribution and can cause many important diseases. We here report the synthesis of new 14 quinoxaline derivatives and the
Carta, Antonio, Sanna, Giuseppina, Briguglio, Irene, Madeddu, Silvia, Vitale, Gabriella, Piras, Sandra, Corona, Paola, Peana, Alessandra Tiziana, Laurini, Erik, Fermeglia, Maurizio, Pricl, Sabrina, Serra, Alessandra, Carta, Elisa, Loddo, Roberta, Giliberti, Gabriele   +14 more
openaire   +3 more sources

Hole‐Selective Self‐Assembled Monolayers Overlaid on NiOx or PEDOT:PSS for Tin‐Based Perovskite Solar Cells – An Overview of Recent Characterization Methods

Chemistry – A European Journal, EarlyView.
Successfully applying self‐assembled monolayers with hole‐selectivity for lead‐free tin perovskite solar cells requires judicious investigation with appropriately powerful characterization methods, in addition to efforts in the development of new materials and processing.
Donghoon Song, Seung Wook Shin, Hui‐Ping Wu, Eric Wei‐Guang Diau   +3 more
wiley   +1 more source

Effects of an Unusual Poison Identify a Lifespan Role for Topoisomerase 2 in Saccharomyces Cerevisiae [PDF]

, 2017
A progressive loss of genome maintenance has been implicated as both a cause and consequence of aging. Here we present evidence supporting the hypothesis that an age-associated decay in genome maintenance promotes aging in Saccharomyces cerevisiae (yeast)
Baxter, Bonnie, Gilbertson, Matthew, Goldfarb, David S., Madrey, Joe, Millen, Jonathan, Nitiss, John L., Piazza, Gary A., Polevoda, Bogdan, Rapaport, Matan, Rasmussen, Lynn, Tombline, Gregory, Van Meter, Michael, Wennerberg, Kirster, White, E. Lucile   +13 more
core   +2 more sources

Synthesis of Quinoxaline Derivatives from Benzofuroxan(Part II) [PDF]

Journal of the Korean Chemical Society, 2004
and Jae Hyuck HurDepartment of Chemistry, Catholic University of Daegu, Gyeongsan 712-702, Korea(Received April 1, 2004)요약. Benzofuroxan과 ethyl acetoacetate를 반응시켜 2-ethoxycarbonyl-3-methylquinoxaline 1,4-dioxide (8)를합성하고, 이것을 hydrazine hydrate 또는 selenium dioxide와 반응시켜 2-hydrazinocarbonyl-3-methylquinoxaline1,4-dioxide (9) 또는 2-ethoxycarbonyl-3 ...
Ho-Sik Kim, Jae-Hyuck Hur
openaire   +1 more source

In Silico Studies of Quinoxaline-2-Carboxamide 1,4-di-N-Oxide Derivatives as Antimycobacterial Agents

Molecules, 2014
Molecular modelling studies were performed on some previously reported novel quinoxaline-2-carboxamide 1,4-di-N-oxide derivatives (series 1–9). Using the LigandScout program, a pharmacophore model was developed to further optimize the antimycobacterial ...
Awwad A. Radwan, Wael M. Abdel-Mageed
doaj   +1 more source

Photochemistry of Aromatic N‐Oxides in Water Probed by Time‐Resolved X‐ray Absorption Spectroscopy

Chemistry – A European Journal, EarlyView.
Time‐resolved XAS at the nitrogen and oxygen K‐edges is applied to the photorearrangement of two N‐oxides in water. Pyridine N‐oxide rapidly forms the oxaziridine isomer. Pyridazine N‐oxide undergoes ring opening to the diazo compound, without any evidence of intermediates.
Maximilian Paradiz Domínguez, Robby Büchner, Mattis Fondell, Albert M. Brouwer   +3 more
wiley   +1 more source