Results 101 to 110 of about 17,555 (209)
The Emerging Role of Rab5 in Membrane Receptor Trafficking and Signaling Pathways
Biochemistry Research International, 2020 Ras analog in brain (Rab) proteins are small guanosine triphosphatases (GTPases) that belong to the Ras-like GTPase superfamily, and they can regulate vesicle trafficking.
Wanqiong Yuan, Chunli Song
doaj +1 more source
, 2014 Rab5 is a small GTPase that regulates early endosome trafficking and other cellular processes, including cell adhesion and migration. Specifically, Rab5 promotes Rac1 activation and cancer cell migration, but little is known about the upstream regulators
Mendoza, Pablo +7 more
core +1 more source
A single discrete Rab5-binding site in phosphoinositide 3-kinase β is required for tumor cell invasion [PDF]
, 2019 Phosphoinositide 3-kinase β (PI3Kβ) is regulated by receptor tyrosine kinases (RTKs), G protein–coupled receptors (GPCRs), and small GTPases such as Rac1 and Rab5.
Gong, Grace Q. +14 more
core +1 more source
Rab5 is required for early events during autophagosome biogenesis.
, 2019 (A) Clones of fat body cell deprived of any Rab5 product were generated by heat shock-Flp/FRT mitotic recombination of the Rab52-null, deletion allele, in fed or 2h-starved animals in presence of myc-tagged PI(3)P biosensor (GFP:myc:FYVE) expressed in ...
Pierre Leopold (6317054) +3 more
core +1 more source
Videos for MRC5 cells stably expressing GFP-Rab5
, 2021 Videos of MRC5 cells stably expressing GFP ...
Nickolay Korabel +2 more
core +1 more source
Rab5 and Alsin regulate stress-activated cytoprotective signaling on mitochondria
, 2017 Mitochondrial stress response is essential for cell survival, and damaged mitochondria are a hallmark of neurodegenerative diseases. It is thus fundamental to understand how mitochondria relay information within the cell.
Charles Ferguson +5 more
core +1 more source
Exploring the PI3Kβ-Rab5 Interface
, 2018 Class I Phosphoinositide 3-kinases (PI3Ks) are lipid kinases that regulate cell motility, growth, and survival. Class IA PI3Ks are obligate heterodimers that contain a regulatory subunit (p85α/β, p55α/γ, or p50α) and a catalytic (p110α, β, or δ) subunit.
Heitz, Samantha
core
cDNA Cloning of a Rab5 Homologue in Babesia gibsoni
Journal of Veterinary Medical Science, 2003 For studying protein trafficking in Babesia-infected erythrocyte, we describe the cloning of a Rab5, one of molecular marker for vesicle trafficking in eukaryotic cells, gene homologue in Babesia gibsoni (BgRab5). The full-length cDNA of BgRab5 is 1,020 bp long with an open reading frame encoding a protein of 220 amino acids.
ZHOU, Jinlin +3 more
openaire +3 more sources
The Rab5 effector Rabankyrin-5 regulates and coordinates different endocytic mechanisms.
PLoS Biology, 2004 The small GTPase Rab5 is a key regulator of clathrin-mediated endocytosis. On early endosomes, within a spatially restricted domain enriched in phosphatydilinositol-3-phosphate [PI(3)P], Rab5 coordinates a complex network of effectors that functionally ...
Carsten Schnatwinkel +6 more
doaj +1 more source
PLoS ONE, 2014 Rab5, the prototypical Rab GTPase and master regulator of the endocytic pathway, is encoded as three differentially expressed isoforms, Rab5A, Rab5B and Rab5C.
Pin-I Chen +5 more
doaj +1 more source