Results 91 to 100 of about 85,005 (197)

Systems Analysis Implicates WAVE2 Complex in the Pathogenesis of Developmental Left-Sided Obstructive Heart Defects. [PDF]

, 2020
Genetic variants are the primary driver of congenital heart disease (CHD) pathogenesis. However, our ability to identify causative variants is limited.
Bernstein, Daniel, Bisgrove, Brent W, Brueckner, Martina, Chung, Wendy K, Deanfield, John, Demarest, Bradley, Edwards, Jonathan J, Fernandez, Nicolas F, Gelb, Bruce D, Giardini, Alessandro, Goldmuntz, Elizabeth, Kim, Richard, Lachmann, Alexander, Lifton, Richard P, Ma'ayan, Avi, Newburger, Jane W, Porter, George, Roberts, Amy E, Rouillard, Andrew D, Seidman, Christine E, Shankaran, Sunita S, Srivastava, Deepak, Tristani-Firouzi, Martin, Turan, Nahid, Wang, Zichen, Yost, H Joseph   +25 more
core  

Requirements for Both Rac1 and Cdc42 in Membrane Ruffling and Phagocytosis in Leukocytes [PDF]

, 1997
Dianne Cox, Peter Chang, Qing Zhang, Pabbathi G. Reddy, Gary Bokoch, Steven M. Greenberg   +5 more
openalex   +1 more source

Cdc42 and Rac1 Regulate the Interaction of IQGAP1 with β-Catenin [PDF]

, 1999
Masaki Fukata, Shinya Kuroda, Masato Nakagawa, Aie Kawajiri, Naohiro Itoh, Ikuo Shoji, Yoshiharu Matsuura, Shin Yonehara, Hajime Fujisawa, Akira Kikuchi, Kozo Kaibuchi   +10 more
openalex   +1 more source

Hyaluronic Acid (Ha) Binding to Cd44 Activates Rac1 and Induces Lamellipodia Outgrowth [PDF]

, 2000
Snezhana Oliferenko, Irina Kaverina, J. Victor Small, Lukas A. Huber   +3 more
openalex   +1 more source

Quercetin suppresses ROS production and migration by specifically targeting Rac1 activation in gliomas

Frontiers in Pharmacology
P66Shc and Rac1 proteins are responsible for tumor-associated inflammation, particularly in brain tumors characterized by elevated oxidative stress and increased reactive oxygen species (ROS) production.
Rafia A. Baba, Rafia A. Baba, Hilal A. Mir, Hilal A. Mir, Taseem A. Mokhdomi, Hina F. Bhat, Ajaz Ahmad, Firdous A. Khanday   +7 more
doaj   +1 more source

Rac1 Regulates Stress-induced, Redox-dependent Heat Shock Factor Activation [PDF]

, 2000
Michitaka Ozaki, Shailesh S. Deshpande, Piamsook Angkeow, Seiichi Suzuki, Kaikobad Irani   +4 more
openalex   +1 more source

Vav2 Is an Activator of Cdc42, Rac1, and RhoA [PDF]

, 2000
Karon Abe, Kent L. Rossman, Betty Liu, Kimberly Ritola, Derek Y. Chiang, Sharon L. Campbell, Keith Burridge, Channing J. Der   +7 more
openalex   +1 more source

PTPσ inhibitors promote hematopoietic stem cell regeneration. [PDF]

, 2019
Receptor type protein tyrosine phosphatase-sigma (PTPσ) is primarily expressed by adult neurons and regulates neural regeneration. We recently discovered that PTPσ is also expressed by hematopoietic stem cells (HSCs).
Chute, John P, Damoiseaux, Robert, Diers, Emelyne, Fang, Tiancheng, Himburg, Heather, Jin Gim, Hyo, Jung, Michael E, Kan, Jenny, Li, Michelle, McBride, William, Pohl, Katherine, Quarmyne, Mamle, Roos, Martina, Termini, Christina M, Whitelegge, Julian, Yan, Xiao, Zhang, Yurun, Zhao, Liman   +17 more
core   +1 more source

Akt Protein Kinase Inhibits Rac1-GTP Binding through Phosphorylation at Serine 71 of Rac1 [PDF]

, 2000
Taegun Kwon, Do Yoon Kwon, Jaesun Chun, Jae‐Hong Kim, Sang Sun Kang   +4 more
openalex   +1 more source

Study on synergistic effect of Rac1 inhibitor and temozolomide in inhibiting proliferation and invasiveness of glioma cells in vitro

Chinese Journal of Contemporary Neurology and Neurosurgery, 2016
Objective To investigate whether Rac1 inhibitor has a synergistic effect on temozolomide (TMZ) in inhibiting the proliferation, migration and invasiveness of glioma cells.  Methods Human glioma cell lines U87 and U251 were cultured by Rac1 inhibitor,
Xiao-yong HAN, Xi-rui WANG, Zhi-huang ZHAO, Jin-xing SHANG, Gang-feng YIN, Xue-jun YANG   +5 more
doaj