Tiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migration. [PDF]
, 2012 Migrating cells acquire front-rear polarity with a leading edge and a trailing tail for directional movement. The Rac exchange factor Tiam1 participates in polarized cell migration with the PAR complex of PAR3, PAR6, and atypical protein kinase C ...
Collard, John G +14 more
core
Altered focal adhesion regulation correlates with cardiomyopathy in mice expressing constitutively active rac1 [PDF]
, 2000 Mark A. Sussman +7 more
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Nerve Growth Factor-induced Neuronal Differentiation Requires Generation of Rac1-regulated Reactive Oxygen Species [PDF]
, 2000 Kazumi Suzukawa +6 more
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rac1 Regulates a Cytokine-Stimulated, Redox-Dependent Pathway Necessary for NF-κB Activation
, 1996 David J. Sulciner +5 more
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Vav2 Activates Rac1, Cdc42, and RhoA Downstream from Growth Factor Receptors but Not β1 Integrins [PDF]
, 2000 Betty P. Liu, Keith Burridge
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A Rac1 Effector Site Controlling Mitogenesis through Superoxide Production
, 1998 Tom Joneson, Dafna Bar‐Sagi
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Selective Alterations in Biosynthetic and Endocytic Protein Traffic in Madin-Darby Canine Kidney Epithelial Cells Expressing Mutants of the Small GTPase Rac1 [PDF]
, 2000 Tzuu‐Shuh Jou +5 more
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Gradients of Rac1 Nanoclusters Support Spatial Patterns of Rac1 Signaling
Cell Reports, 2017 Summary: Rac1 is a small RhoGTPase switch that orchestrates actin branching in space and time and protrusion/retraction cycles of the lamellipodia at the cell front during mesenchymal migration.
Amanda Remorino +9 more
doaj
The Rac1/p38 Mitogen-activated Protein Kinase Pathway Is Required for Interferon α-dependent Transcriptional Activation but Not Serine Phosphorylation of Stat Proteins [PDF]
, 2000 Shahab Uddin +8 more
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