Randomized Clinical Trial Comparing The Effect Of Oral Rehydration Therapy With And Without Racecadotril In The Management Of Acute Diarrhea In Children [PDF]
Objective: This study aimed to investigate the beneficial effect of racecadotril in children with acute diarrheal illness. Methods: This randomized case-control study was conducted at Watim General Hospital over four months from April to July 2023.
Sughra Zulfiqar +5 more
doaj +5 more sources
Integrating metabolomics, bionics, and culturomics to study probiotics-driven drug metabolism [PDF]
Many drugs have been shown to be metabolized by the human gut microbiome, but probiotic-driven drug-metabolizing capacity is rarely explored. Here, we developed an integrated metabolomics, culturomics, and bionics framework for systematically studying ...
Bohai Li +17 more
doaj +5 more sources
Racecadotril in the management of diarrhea: an underestimated therapeutic option? [PDF]
Acute infectious diarrhea (AID) represents an important clinical entity both regarding morbidity and mortality rates, even in industrialized countries, and it leads to one of the major public health burdens, among gastroenterological diseases, with ...
Marco Manfredi +4 more
doaj +3 more sources
Analysis of Racecadotril in Pharmaceutical Formulations Using Ultra Performance Liquid Chromatography (UPLC) Method [PDF]
Objective:In this study, a simple and selective ultra-performance liquid chromatography method for the determination of racecadotril in pharmaceutical dosage forms has been developed.Methods:The method is in reverse phase C18 column; based on the ...
Armağan ÖNAL, Emrullah BİNAY
doaj +4 more sources
Racecadotril for acute diarrhoea in children. [PDF]
Acute diarrhoea is a leading cause of death for children under five years of age. Most deaths are caused by excessive fluid and electrolyte losses. Racecadotril is an anti-secretory drug that has been used for acute diarrhoea in children as an adjunct to oral rehydration therapy.To assess the efficacy and safety of racecadotril for treating acute ...
Liang Y +4 more
europepmc +6 more sources
Cost utility, budget impact, and scenario analysis of racecadotril in addition to oral rehydration for acute diarrhea in children in Malaysia [PDF]
Tamlyn Anne Rautenberg,1,2 Ute Zerwes,3 Way Seah Lee4 1IGES Institut GmbH, Berlin, Germany; 2Health Economics and HIV/AIDS Research Division (HEARD), University of KwaZulu-Natal, Durban, KwaZulu-Natal, South Africa; 3Assessment in Medicine GmbH, Lö ...
Rautenberg TA, Zerwes U, Lee WS
doaj +3 more sources
Racecadotril in the treatment of acute diarrhea in children: a systematic, comprehensive review and meta-analysis of randomized controlled trials [PDF]
Background Racecadotril is a guideline-recommended option for the treatment of acute diarrhea in children but existing guidelines and previous reviews of the field are based on a small fraction of published evidence.
Marion Eberlin +3 more
doaj +4 more sources
Racecadotril versus loperamide for the treatment of acute diarrhoea [PDF]
Poulami Roy, Novonil Deb
doaj +3 more sources
Understanding the Anti-Diarrhoeal Properties of Incomptines A and B: Antibacterial Activity against Vibrio cholerae and Its Enterotoxin Inhibition [PDF]
Incomptines A (IA) and B (IB) are two sesquiterpene lactones with antiprotozoal, antibacterial, cytotoxic, antitumor, spermicidal, and phytotoxic properties.
Fernando Calzada +7 more
doaj +2 more sources
Jose ChacónOn behalf of the Racecadotril Post-authorization Record Group; Centro Clinico Profesional Caracas, Caracas, VenezuelaAbstract: Drug efficacy might differ from clinical trial results when performed in clinical daily conditions ...
Jose Chacón
doaj +4 more sources

