Randomized trial to assess the efficacy and safety of xyloglucan for the treatment of acute gastroenteritis in children. [PDF]
Xyloglucan is effective and safe in moderate‐to‐severe diarrhea in children 3 months to 5 years. Abstract Acute gastroenteritis is one of the most common diseases in children and an important cause of morbidity and mortality worldwide. No specific treatment is available; therefore, management is exclusively symptomatic.
Perez-Garcia MJ +17 more
europepmc +2 more sources
Racecadotril for childhood gastroenteritis: an individual patient data meta-analysis
Racecadotril is an antidiarrhoeal drug with intestinal antisecretory mechanism of action.To assess racecadotril efficacy as an adjunct to oral rehydration solution, against oral rehydration solution alone or with placebo in childhood acute gastroenteritis.Individual patient data meta-analysis following multilevel mixed models testing the significance ...
Philippe, Lehert +7 more
openaire +3 more sources
Racecadotril for acute diarrhoea in children: systematic review and meta-analyses [PDF]
OBJECTIVE Racecadotril is an antisecretory agent that can prevent fluid/electrolyte depletion from the bowel as a result of acute diarrhoea, without affecting intestinal motility. An up-to-date systematic review is indicated to summarise the evidence on
Morris Gordon, Anthony K Akobeng
openalex +3 more sources
El racecadotril fue efectivo como coadyuvante en el tratamiento de la diarrea aguda en niños.
Alfredo Gaete
doaj +3 more sources
Racecadotril was effective for severe watery diarrhea in children [PDF]
M. Datta
openaire +3 more sources
Background and aim Previous studies have shown that Racecadotril is safer and more effective in treating children with acute diarrhea. This study aimed to evaluate the effect of Racecadotril as a booster to oral rehydration solution in the management of ...
Reham M Sayed +2 more
doaj +1 more source
RACECADOTRIL IN ACUTE WATERY DIARRHEA IN CHILDREN
Maha Singh, Alka Yadav, Sanjeev Nanda
openaire +2 more sources
Clinical Characteristics and Safety Profiles of Japanese Psoriasis Patients Who Continued Apremilast Treatment for 6 and 12 Months: A Post Hoc Analysis of an Apremilast Postmarketing Surveillance Study. [PDF]
ABSTRACT Apremilast is a phosphodiesterase 4 inhibitor approved for moderate to severe psoriasis in Japan. Apremilast significantly improved Physician's Global Assessment (PGA) and Dermatology Life Quality Index (DLQI) both at 6 and 12 months in a previously published primary post‐surveillance study.
Ohtsuki M +8 more
europepmc +2 more sources
Enhancement of dissolution rate of racecadotril by liquisolid compact technology
The current investigation was used to improve the rate of dissolution of an anti-diarrheal drug i.e., racecadotril (RT) at low pH conditions (i.e., in the stomach) by reducing the water secretion and electrolyte in to the intestine by liquisolid tablets.
Bhaskar Daravath, Shalini Somalanka
doaj +1 more source
Neprilysin inhibition for pulmonary arterial hypertension: a randomized, double-blind, placebo-controlled, proof-of-concept trial. [PDF]
This is the peer reviewed version of the following article: Hobbs AJ, Moyes AJ, Baliga RS, et al. Neprilysin inhibition for pulmonary arterial hypertension: a randomized, double‐blind, placebo‐controlled, proof‐of‐concept trial. Br J Pharmacol.
Hobbs AJ +14 more
europepmc +3 more sources

