Results 21 to 30 of about 1,478 (205)

Role of Racecadotril in Children with Acute Diarrhea

Dhaka Shishu (Children) Hospital Journal, 2021
Background: Diarrhea is a leading cause of illness and death among children in developing countries. Racecadotril (acetorphan), an enkephalinase inhibitor with antisecretory and anti-diarrheal actions, is an effective and safe treatment for acute diarrhea in adults and children. Objectives: The objective of this study is to evaluate the efficacy ...
Sheikh Farjana Sonia, Sharmin Afroze, Kazi Iman, Uzzal Kumar Ghosh, Shahidul Islam, Parijat Bishwas, Azmeri Sultana   +6 more
openaire   +2 more sources

Stereoselective Bio-Organocatalytic Cascade to Chiral Amides as Active Pharmaceutical Ingredient Intermediates Using ω-Transaminase and Choline Chloride Under Microwave Irradiation. [PDF]

ChemSusChem
Amide bond formation is central to active pharmaceutical ingredient (API) synthesis. A bio‐organocatalytic cascade is reported, merging stereoselective ω‐transaminase (ω‐TA) transamination in neat organic solvent with choline chloride‐mediated amidation under solvent‐free microwave conditions.
Romano S, Damian M, Nardi M, Procopio A, Strähler S, Preschel D, Oliverio M, Mutti FG.   +7 more
europepmc   +2 more sources

Randomized trial to assess the efficacy and safety of xyloglucan for the treatment of acute gastroenteritis in children. [PDF]

Food Sci Nutr, 2023
Xyloglucan is effective and safe in moderate‐to‐severe diarrhea in children 3 months to 5 years. Abstract Acute gastroenteritis is one of the most common diseases in children and an important cause of morbidity and mortality worldwide. No specific treatment is available; therefore, management is exclusively symptomatic.
Perez-Garcia MJ, Royuela A, Rodriguez-Contreras FJ, PandoBravo MA, Chiatti C, Ramos C, Arana-Zumaquero M, Gonzalez-Marcos MI, Diaz J, Fresno-Calle MC, García-Bartolomé R, Viver S, Villaverde-Gonzalez S, Cilleruelo-Pascual ML, Gutierrez-Junquera C, Rasines-Rodriguez A, Manso-Pérez A, Román-Riechmann E.   +17 more
europepmc   +2 more sources

The efficacy of lactobacillus reuteri in conjunction with racecadotril in managing pediatric rotavirus enteritis and its impact on intestinal mucosa and immune function. [PDF]

Afr Health Sci
Background This study aimed to evaluate the effectiveness of combining Lactobacillus reuteri with racecadotril in treating pediatric rotavirus enteritis, focusing on its impact on intestinal mucosa and immune function.
He Z, Lan L, Chen N, Cheng Y, Gong S.
europepmc   +2 more sources

Future Prospects of Imatinib in Advanced Pulmonary Hypertension Management. [PDF]

IUBMB Life
ABSTRACT Pulmonary arterial hypertension (PAH) is a severe, progressive disease characterized by elevated pulmonary arterial pressure and increased vascular resistance. This hemodynamic strain forces the right ventricle to pump against a high‐pressure system, ultimately leading to right‐sided heart failure and death.
Davì F, Mangione S, Iaconis A, Genovese T, Tranchida N, Cuzzocrea S.   +5 more
europepmc   +2 more sources

Efficacy of Racecadotril in a Patient Affected by a Therapy-Refractory VIPoma and Carcinoid Syndrome. [PDF]

JCEM Case Rep
Neuroendocrine neoplasms (NENs) encompass a heterogeneous spectrum of tumors originating from the diffuse neuroendocrine cell system. Approximately 30% of NEN exhibit functional activity with clinical syndromes through hormone-mediated effects ...
Boesenkoetter J, Ellrichmann I, Konukiewitz B, Ellrichmann M, Schulte DM.   +4 more
europepmc   +2 more sources

Role of antisecretory drug in treatment of children with acute watery diarrhea: A Randomized Controlled Trial

Al-Azhar Assiut Medical Journal, 2022
Background and aim Previous studies have shown that Racecadotril is safer and more effective in treating children with acute diarrhea. This study aimed to evaluate the effect of Racecadotril as a booster to oral rehydration solution in the management of ...
Reham M Sayed, Hosny M.A El-Masry, Ismail Abd El-Razek Kasem   +2 more
doaj   +1 more source

Hospital Based Prospective Observational Study to Audit the Prescription Practices and Outcomes of Paediatric Patients (6 months to 5 years age group) Presenting with Acute Diarrhea [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Diarrhea is a leading killer of children, accounting for 9% of all deaths among under-five children worldwide. WHO protocol deviation in management of diarrheas in children is likely due to various reasons.
Tapobrata De, Santosh Kondekar, Surbhi Rathi   +2 more
doaj   +1 more source

ACUTE GASTROENTERITIS IN CHILDREN-THERAPEUTIC PRINCIPLES [PDF]

Romanian Journal of Pediatrics, 2008
This report presents updated recommendations for the optimal management of acute gastroenteritis in childhood, according to fundamental therapeutical principles recommended by ESPGHAN ( European Society of Paediatric Gastroenterology, Hepatology and ...
Victoria Hurduc, Valeriu Popescu, Dimitrie Dragomir, Doina Pleșca, Luiza Preda   +4 more
doaj   +1 more source

Concomitant medication in patients with bradykinin‐mediated angioedema – there's more than ACE inhibitors

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 21, Issue 11, Page 1283-1289, November 2023., 2023
Summary Bradykinin‐mediated angioedema is a rare, non‐allergic, potentially life‐threatening disease. ACE inhibitor‐induced angioedema and hereditary angioedema (HAE) are the two most common presentations. Therapeutic options, pathophysiology and diagnosis continue to be investigated, with considerable progress in HAE over the last few decades. For all
Robin Lochbaum, Thomas K. Hoffmann, Jens Greve, Janina Hahn   +3 more
wiley   +1 more source