Results 31 to 40 of about 993 (170)
Comparison of racecadotril and loperamide in children with acute diarrhoea [PDF]
Alimentary Pharmacology & Therapeutics, 1999 MethodsA multicentre, parallel‐group, double‐blind, double‐placebo study was carried out to compare the efficacy, tolerability, and safety of racecadotril and loperamide in children aged 2 to 10 years who were suffering from acute diarrhoea. Patients received racecadotril (1.5 mg/kg) or loperamide (0.03 mg/kg) three times daily plus matching placebo ...
N. Fretault +3 more
openaire +3 more sources
British Journal of Pharmacology, Volume 180, Issue 7, Page 879-893, April 2023., 2023 Despite the increasing impact of opioid use disorders on society, there is a disturbing lack of effective medications for their clinical management. An interesting innovative strategy to treat these disorders consists in the protection of endogenous opioid peptides to activate opioid receptors, avoiding the classical opioid‐like side effects.
Beltran Alvarez‐Perez +2 more
wiley +1 more source
United European Gastroenterology Journal, Volume 10, Issue 6, Page 556-584, July 2022., 2022 Abstract Irritable bowel syndrome with diarrhoea (IBS‐D) and functional diarrhoea (FDr) are the two major functional bowel disorders characterized by diarrhoea. In spite of their high prevalence, IBS‐D and FDr are associated with major uncertainties, especially regarding their optimal diagnostic work‐up and management.
Edoardo Savarino +29 more
wiley +1 more source
Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022 Objective. To evaluate the clinical efficacy and safety of Gegen Qinlian decoction in the treatment of pediatric diarrhea. Methods. A search for relevant RCTs was performed from which a systematic review and meta‐analysis was conducted. This meta‐analysis was registered at INPLASY (reference number ID: INPLASY202180105). Results.
Dan Wang +7 more
wiley +1 more source
Frontiers in Medicine, 2016 Racecadotril is a guideline-recommended treatment to alleviate symptoms of acute diarrhea. A systematic review of randomized studies was performed comparing efficacy and safety of treatment with racecadotril to that with placebo or active treatments in ...
Wolfgang Fischbach +4 more
doaj +1 more source
Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022 Diarrhea, occurring due to intestinal flora disturbance, is potentially lethal, and its current treatments have adverse effects such as constipation and vomiting. Camelina sativa oil (CSO) is a cooking ingredient and natural remedy used in several countries; however, its pharmacological effects on intestinal health remain unknown. Here, we explored the
Jie Zhu +8 more
wiley +1 more source
Gelatin tannate for acute childhood gastroenteritis: a randomized, single-blind controlled trial [PDF]
, 2016 Background Oral rehydration therapy is the recommended treatment for acute childhood gastroenteritis. The aim of this study was to assess the efficacy and safety of gelatin tannate plus oral rehydration compared with oral rehydration alone.
Aloi, Marina +5 more
core +1 more source
Treatment of Acute Diarrhoea: Past and Now [PDF]
, 2015 Context: Since ancient times diarrhoea has been a highly fatal disease and even today diarrhoea, the topic of this review, is a problem affecting millions of people around the world despite the efforts of governments and professionals from the medical ...
Caramia, Giuseppe +3 more
core +2 more sources
BioMed Research International, Volume 2022, Issue 1, 2022., 2022 Background. Diarrheal diseases are a major cause of morbidity and mortality throughout the world and particularly in developing countries. Nauclea diderrichii is a plant used in traditional medicine in the treatment of anemia, fever, gastric ulcer, malaria, abdominal pain, skin infections, and diarrhea.
R. C. Douho Djimeli +6 more
wiley +1 more source
Role of Racecadotril in Children with Acute Diarrhea
Dhaka Shishu (Children) Hospital Journal, 2021 Background: Diarrhea is a leading cause of illness and death among children in developing countries. Racecadotril (acetorphan), an enkephalinase inhibitor with antisecretory and anti-diarrheal actions, is an effective and safe treatment for acute diarrhea in adults and children. Objectives: The objective of this study is to evaluate the efficacy ...
Parijat Bishwas +6 more
openaire +2 more sources