Results 31 to 40 of about 1,478 (205)

Racecadotril for acute diarrhoea in children: systematic review and meta-analyses [PDF]

, 2015
OBJECTIVE Racecadotril is an antisecretory agent that can prevent fluid/electrolyte depletion from the bowel as a result of acute diarrhoea, without affecting intestinal motility. An up-to-date systematic review is indicated to summarise the evidence on
Alam, Alvarez Calatayud, Anthony Akobeng, Bruzzese, Cojocaru, Cézard, Eberlin, Freedman, Gill, Guarino, Gutierrez Castrellon, Higgins, Higgins, Huighebaert, Lehert, Mehta, Melendez Garcia, Morris Gordon, Nataro, Pieścik-Lech, Pitkin, Rao, Rautenberg, Riddle, Salazar-Lindo, Sands, Santos, Savitha, Szajewska, Tebruegge, Tormo, Turck   +31 more
core   +1 more source

Medikamente als Auslöser Bradykinin‐vermittelter Angioödeme – mehr als ACE‐Hemmer

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 21, Issue 11, Page 1283-1290, November 2023., 2023
Zusammenfassung Bradykinin‐vermittelte Angioödeme sind seltene, nichtallergische und potenziell lebensbedrohliche Krankheiten. Die beiden bekanntesten Formen sind das ACE‐Hemmer‐induzierte Angioödem und das hereditäre Angioödem (HAE). Die therapeutischen Möglichkeiten, die Pathophysiologie und die Diagnostik werden weiter erforscht, wobei beim HAE in ...
Robin Lochbaum, Thomas K. Hoffmann, Jens Greve, Janina Hahn   +3 more
wiley   +1 more source

A comprehensive comparison of the efficacy and tolerability of racecadotril with other treatments of acute diarrhea in adults

Frontiers in Medicine, 2016
Racecadotril is a guideline-recommended treatment to alleviate symptoms of acute diarrhea. A systematic review of randomized studies was performed comparing efficacy and safety of treatment with racecadotril to that with placebo or active treatments in ...
Wolfgang Fischbach, Viola Andresen, Marion Eberlin, Tobias Mück, Peter Layer   +4 more
doaj   +1 more source

Clinical Characteristics and Safety Profiles of Japanese Psoriasis Patients Who Continued Apremilast Treatment for 6 and 12 Months: A Post Hoc Analysis of an Apremilast Postmarketing Surveillance Study. [PDF]

J Dermatol
ABSTRACT Apremilast is a phosphodiesterase 4 inhibitor approved for moderate to severe psoriasis in Japan. Apremilast significantly improved Physician's Global Assessment (PGA) and Dermatology Life Quality Index (DLQI) both at 6 and 12 months in a previously published primary post‐surveillance study.
Ohtsuki M, Okubo Y, Saeki H, Igarashi A, Imafuku S, Abe M, Saito K, Ogawa R, Morita A.   +8 more
europepmc   +2 more sources

Gelatin tannate for acute childhood gastroenteritis: a randomized, single-blind controlled trial [PDF]

, 2016
Background Oral rehydration therapy is the recommended treatment for acute childhood gastroenteritis. The aim of this study was to assess the efficacy and safety of gelatin tannate plus oral rehydration compared with oral rehydration alone.
Aloi, Marina, Cucchiara, Salvatore, Frassanito, Antonella, Mennini, Maurizio, Midulla, Fabio, Tolone, Carlo   +5 more
core   +1 more source

Recent progress in orodispersible films‐mediated therapeutic applications: A review

MedComm – Biomaterials and Applications, Volume 2, Issue 2, June 2023., 2023
The current therapeutic applications of orodispersible films (ODFs) are delivered either locally or systemically for potential patients suffering from various diseases, including oral inflammation, cardiovascular diseases, pain disorders, nausea and vomiting, mood or mental disorders, erectile dysfunction and pulmonary diseases Abstract Orodispersible ...
Yu Tian, Jiangtao Lin, Hongshu Jing, Quan Wang, Zhihua Wu, Yourong Duan   +5 more
wiley   +1 more source

Effects of neprilysin and neprilysin inhibitors on glucose homeostasis: Controversial points and a promising arena 脑啡肽酶和脑啡肽酶抑制剂对葡萄糖稳态的影响:一个有争议的观点和有前景的领域

Journal of Diabetes, Volume 15, Issue 5, Page 397-408, May 2023., 2023
Highlights Neprilysin (NEP) inhibitors may lead to beneficial effects through inhibition of NEP, which involves impairment of glucose homeostasis through modulation of insulin resistance and the development of pancreatic β cell dysfunction as observed in type 2 diabetes mellitus.
Faisal Holil AlAnazi, Hayder M. Al‐kuraishy, Ali I. Al‐Gareeb, Athanasios Alexiou, Marios Papadakis, Hanan A. Ogaly, Yousef Abud Alanazi, Hebatallah M. Saad, Gaber El‐Saber Batiha   +8 more
wiley   +1 more source

Treatment of Acute Diarrhoea: Past and Now [PDF]

, 2015
Context: Since ancient times diarrhoea has been a highly fatal disease and even today diarrhoea, the topic of this review, is a problem affecting millions of people around the world despite the efforts of governments and professionals from the medical ...
Caramia, Giuseppe, Coman, MARIA MAGDALENA, Silvi, Stefania, Verdenelli, Maria Cristina   +3 more
core   +2 more sources

The inhibition of enkephalin catabolism by dual enkephalinase inhibitor: A novel possible therapeutic approach for opioid use disorders

British Journal of Pharmacology, Volume 180, Issue 7, Page 879-893, April 2023., 2023
Despite the increasing impact of opioid use disorders on society, there is a disturbing lack of effective medications for their clinical management. An interesting innovative strategy to treat these disorders consists in the protection of endogenous opioid peptides to activate opioid receptors, avoiding the classical opioid‐like side effects.
Beltran Alvarez‐Perez, Hervé Poras, Rafael Maldonado   +2 more
wiley   +1 more source

Impact of clinically tested NEP/ACE inhibitors on tumor uptake of [111In-DOTA]MG11 [PDF]

, 2016
Background: We have recently shown that treatment of mice with the neutral endopeptidase (NEP) inhibitor phosphoramidon (PA) improves the bioavailability and tumor uptake of biodegradable radiopeptides.
Jong, M. (Marion) de, Kaloudi, A. (Katerina), Krenning, E.P. (Eric), Lymperis, E. (Emmanouil), Maina, T. (Theodosia), Nock, B.A. (Berthold), Valkema, R. (Roelf)   +6 more
core   +5 more sources