Results 61 to 70 of about 838,261 (308)
Radiation-Resistant Thymic Stem Cells
Experimental Biology and Medicine, 1973 Summary1. Thymus rudiments obtained from 12 to 13 day mouse embryos were irradiated with 250, 500 or 1000 R X-rays and their subsequent morphogenesis studied both in vitro and by transplantation into irradiated host animals.2. Although irradiation had a marked effect on total growth of rudiments, the differentiation of lymphoid cells did not appear to ...
L, Kubai, R, Auerbach
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LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
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Radiation Resistant Silicon Semiconductor Devices-Patent [PDF]
, 1970 Improving radiation resistance of silicon semiconductor junctions by doping with ...
Wysocki, J. J.
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RADIATION RESISTANCE TESTS [PDF]
, 1963 The complex response of polymers to radiation necessitates knowledge of the radiation resistance and of the effects of radiation type, energy, and intensity on the resistance. A brief discussion is given of the types of radiation and their interactions with materials, and the techniques for measuring the amount of energy absorbed in a material from the
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Resistance of Algae to Radiation [PDF]
Nature, 1960 EXPERIMENTS carried out since 1954 have shown that various algae are much more resistant to radiation than are higher plants and animals. The results, which will be published fully elsewhere, are as follows:
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
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Radiation Resistance: Resurrection by Recombination [PDF]
Current Biology, 2007 Adaptation to extreme desiccation has conferred extraordinary radiation resistance on the bacterium Deinococcus radiodurans. How this organism is able to reconstruct a genome shattered by gamma rays has now been revealed.
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Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
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miRNA‐106a and prostate cancer radioresistance: a novel role for LITAF in ATM regulation
Molecular Oncology, 2018 Recurrence of high‐grade prostate cancer after radiotherapy is a significant clinical problem, resulting in increased morbidity and reduced patient survival.
Christianne Hoey +8 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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