Results 31 to 40 of about 2,471 (195)
Frontiers in Chemistry, 2021 The ability to radiolabel proteins with [18F]fluoride enables the use of positron emission tomography (PET) for the early detection, staging and diagnosis of disease.
Kymberley R. Scroggie +2 more
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Molecules, 2022 Isocitrate dehydrogenases (IDHs) are metabolic enzymes commonly mutated in human cancers (glioma, acute myeloid leukaemia, chondrosarcoma, and intrahepatic cholangiocarcinoma).
Valérie Weber +11 more
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Synthesis, in vitro and in vivo evaluation of 3β-[18F]fluorocholic acid for the detection of drug-induced cholestasis in mice [PDF]
, 2017 Introduction : Drug-induced cholestasis is a liver disorder that might be caused by interference of drugs with the hepatobiliary bile acid transporters. It is important to identify this interference early on in drug development.
De Lombaerde, Stef +7 more
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Recent Advances in Synthetic Methodologies to Form C-18F Bonds
Frontiers in Chemistry, 2022 Positron emission tomography (PET) is an important technique for the early diagnosis of disease. Due to the specific physical and chemical properties of Fluorine-18, this important isotope is widely used in PET for labelling and molecular imaging, and ...
Zhiyi Liu +6 more
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Al18F: A New Standard for Radiofluorination [PDF]
Journal of Nuclear Medicine, 2013 TO THE EDITOR: 18F is the most common radionuclide used in PET imaging, but its application via a rapid, simple, easily accessible labeling procedure has been challenging. We congratulate Wan et al.
Goldenberg, D.M. +3 more
openaire +3 more sources
Synthesis of 18F-labelled 2-fluoro-1,4-quinones using acetylhypofluorite [PDF]
, 1988 The fluorination of 1,4-benzo- and naphthoquinones using [18F]acetylhypofluorite is described.
Herscheid, Jacobus D.M. +3 more
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Fluorine-18-Labeled Fluorescent Dyes for Dual-Mode Molecular Imaging
Molecules, 2020 Recent progress realized in the development of optical imaging (OPI) probes and devices has made this technique more and more affordable for imaging studies and fluorescence-guided surgery procedures.
Maxime Munch +2 more
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Recent Advances in 18F-Labeled Amino Acids Synthesis and Application
Pharmaceutics, 2022 Radiolabeled amino acids are an important class of agents for positron emission tomography imaging that target amino acid transporters in many tumor types.
Chao Wang, Rong Lin, Shaobo Yao
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Methodological advancements in microfluidic and carbonylation PET radiochemistry [PDF]
, 2016 Along with the progress of PET as a powerful imaging tool in medicine, there has been increasing demand for new labeling methods. The main aim of this PhD dissertation was to develop novel labeling methodologies using the positron emitter carbon-11.
Dahl, Kenneth
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A Convenient Route to New (Radio)Fluorinated and (Radio)Iodinated Cyclic Tyrosine Analogs
Pharmaceuticals, 2022 The use of radiolabeled non-natural amino acids can provide high contrast SPECT/PET metabolic imaging of solid tumors. Among them, radiohalogenated tyrosine analogs (i.e., [123I]IMT, [18F]FET, [18F]FDOPA, [123I]8-iodo-L-TIC(OH), etc.) are of particular ...
Maria Noelia Chao +11 more
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