Results 41 to 50 of about 2,508 (203)
Synthesis of 18F-labelled 2-fluoro-1,4-quinones using acetylhypofluorite [PDF]
, 1988 The fluorination of 1,4-benzo- and naphthoquinones using [18F]acetylhypofluorite is described.
Herscheid, Jacobus D.M. +3 more
core +3 more sources
Optimization of PET protocol and interrater reliability of 18F-PSMA-11 imaging of prostate cancer [PDF]
, 2020 Background Several scan parameters for PET imaging with F-18-PSMA-11 such as dosage, acquisition time and scan duration were evaluated to determine the most appropriate scan protocol, as well as the effect of furosemide administration on lesion ...
Achten, Eric +7 more
core +2 more sources
Scientific Reports, 2017 In a relatively short period of time, transition metal-mediated radiofluorination reactions have changed the PET radiochemistry landscape. These reactions have enabled the radiofluorination of a wide range of substrates, facilitating access to ...
Andrew V. Mossine +5 more
doaj +1 more source
Molecules, 2016 Nitric oxide (NO), an important multifunctional signaling molecule, is produced by three isoforms of NO-synthase (NOS) and has been associated with neurodegenerative disorders.
Christian Drerup +2 more
doaj +1 more source
Nickel-Mediated Oxidative Fluorination for PET with Aqueous [\(^{18}F\)] Fluoride [PDF]
, 2012 A one-step oxidative fluorination for carbon–fluorine bond formation from well-defined nickel complexes with oxidant and aqueous fluoride is presented, which enables a straightforward and practical \(^{18}F\) late-stage fluorination of complex small ...
Hooker, Jacob M +2 more
core +1 more source
New AMD3100 derivatives for CXCR4 chemokine receptor targeted molecular imaging studies: synthesis, anti-HIV-1 evaluation and binding affinities [PDF]
, 2015 CXCR4 is a target of growing interest for the development of new therapeutic drugs and imaging agents as its role in multiple disease states has been demonstrated.
Archibald, Stephen J. +14 more
core +2 more sources
Development of novel fluorine-18 labeled PET radioligands for monoamine oxidase B (MAO-B) [PDF]
, 2013 Monoamine oxidases (MAO-A and MAO-B) are important enzymes regulating the levels of monoaminergic neurotransmitters. Selectiv e and irreversible MAO-B inhibitors such as L -deprenyl and rasagiline are clinically used for the t reatment of ...
Nag, Sangram
core +2 more sources
SynOpen, 2017 The first prospective fluorinated PET tracers for imaging hypoxia obtained via thiazolidine-ligation are reported. Three 1,2-thiol-amine linkers were combined with four different 2-nitroimidazole spacers via amide or urea bond formation.
M. Musolino, S. Dall’Angelo, M. Zanda
doaj +1 more source
Synthesis of Fluorine-18 Functionalized Nanoparticles for use as in vivo Molecular Imaging Agents [PDF]
, 2008 Nanoparticles containing fluorine-18 were prepared from block copolymers made by ring opening metathesis polymerization (ROMP). Using the fast initiating ruthenium metathesis catalyst (H_2IMes)(pyr)_2(Cl)_2Ru=CHPh, low polydispersity amphiphilic block ...
, X. K. +54 more
core +3 more sources
Pharmaceuticals, 2021 The incorporation of silicon fluoride acceptor (SiFA) moieties into a variety of molecules, such as peptides, proteins and biologically relevant small molecules, has improved the generation of 18F-radiopharmaceuticals for medical imaging.
Lexi Gower-Fry +12 more
doaj +1 more source