Results 41 to 50 of about 3,496 (254)

Peptides Radiofluorination: Main Methods and Highlights

International Journal of Organic Chemistry, 2022
Ana Carolina A. Bispo, Fernanda A. F. Almeida, Juliana B. Silva, Marcelo Mamede   +3 more
openalex   +3 more sources

Mild, Organo-Catalysed Borono-Deamination as a Key to Late-Stage Pharmaceutical Precursors and 18F-Labelled Radiotracers

Frontiers in Chemistry, 2022
A tris(pentafluorophenyl)borane catalysed method for the synthesis of boronic acid esters from aromatic amines in yields of up to 93% was devised.
Raúl M. Pérez-García, Patrick J. Riss, Patrick J. Riss, Patrick J. Riss, Patrick J. Riss   +4 more
doaj   +1 more source

[18F]Tosyl fluoride as a versatile [18F]fluoride source for the preparation of 18F-labeled radiopharmaceuticals

Scientific Reports, 2023
Positron emission tomography (PET) is an in vivo imaging technology that utilizes positron-emitting radioisotope-labeled compounds as PET radiotracers that are commonly used in clinic and in various research areas, including oncology, cardiology, and ...
Dong Zhou, Wenhua Chu, Jinbin Xu, Sally Schwarz, John A. Katzenellenbogen   +4 more
doaj   +1 more source

Radiosynthesis of 5-[¹⁸F]Fluoro-1,2,3-triazoles through Aqueous Iodine–[¹⁸F]Fluorine Exchange Reaction

Molecules, 2021
In this report, a simple and efficient process to achieve fluorine-18-labeled 1,2,3-triazole is reported. The heteroaromatic radiofluorination was successfully achieved through an iodine–fluorine-18 exchange in an aqueous medium requiring only trace ...
Xiang Zhang, Falguni Basuli, Sameh Abdelwahed, Tadhg Begley, Rolf Swenson   +4 more
doaj   +1 more source

Efforts toward PET-Activatable Red-Shifted Silicon Rhodamines and Silicon Pyronine Dyes

Pharmaceuticals, 2023
Tracers for bimodal optical imaging and positron emission tomography unite multiple advantages in a single molecule. Their tumor-specific uptake can be visualized after their PET activation by radiofluorination via PET/CT or PET/MRI allowing for staging ...
Carsten Sven Kramer, Thines Kanagasundaram, Jessica Matthias, Klaus Kopka   +3 more
doaj   +1 more source

Electrochemical Flash Fluorination and Radiofluorination [PDF]

ChemElectroChem, 2018
AbstractA new method for rapid late‐stage fluorination using the cation pool technique is presented. Fluorination and no‐carrier‐added radiofluorination of methyl (phenylthio) acetate, methyl 2‐(methylthio) acetate, and methyl 2‐(ethylthio) acetate were performed.
Mehrdad Balandeh, Alejandra Rios, Nathanael Allison, Daniela Shirazi, Adrian Gomez, Laura Rambaran, Travis Holloway, Saman Sadeghi   +7 more
openaire   +2 more sources

Tandem Iridium-Catalyzed C-H Borylation/Copper-Mediated Radiofluorination of Aromatic C-H Bonds with [¹⁸F]TBAF. [PDF]

Methods Mol Biol
Morales M, Preshlock S, Sharninghausen LS, Wright JS, Brooks AF, Sanford MS, Scott PJH.   +6 more
europepmc   +2 more sources

An efficient, versatile procedure for the [18F]-radiofluorination of base-sensitive tracers with high radiochemical conversion

Nuclear Medicine and Biology
Alexandros Pappas, Stefan Milton, J. Goos, Niki Constantinou, Staffan Holmin   +4 more
semanticscholar   +2 more sources

Radiochemistry with {Al18F}2+: Current status and optimization perspectives for efficient radiofluorination by complexation

Coordination chemistry reviews, 2023
S. Schmitt, E. Moreau
semanticscholar   +3 more sources

Radiofluorination using aluminum-fluoride (Al18F) [PDF]

EJNMMI Research, 2013
Targeted agents are increasingly used for treating cancer and other diseases, but patients may need to be carefully selected to maximize the potential for therapeutic benefit. One way to select patients is to bind an imaging radionuclide to a targeting agent of interest, so that its uptake in specific sites of disease can be visualized by positron ...
McBride, William J, Sharkey, Robert M, Goldenberg, David M   +2 more
openaire   +2 more sources