Results 41 to 50 of about 3,410 (215)

Fluorine-18-Labeled Fluorescent Dyes for Dual-Mode Molecular Imaging

Molecules, 2020
Recent progress realized in the development of optical imaging (OPI) probes and devices has made this technique more and more affordable for imaging studies and fluorescence-guided surgery procedures.
Maxime Munch, Benjamin H. Rotstein, Gilles Ulrich   +2 more
doaj   +1 more source

Recent Development of Radiofluorination of Boron Agents for Boron Neutron Capture Therapy of Tumor: Creation of 18F-Labeled C-F and B-F Linkages

Pharmaceuticals, 2023
Boron neutron capture therapy (BNCT) is a binary therapeutic technique employing a boron agent to be delivered to the tumor site followed by the irradiation of neutrons.
Jingwen Deng, Chung-Shan Yu
semanticscholar   +1 more source

Reaction of [18F]Fluoride at Heteroatoms and Metals for Imaging of Peptides and Proteins by Positron Emission Tomography

Frontiers in Chemistry, 2021
The ability to radiolabel proteins with [18F]fluoride enables the use of positron emission tomography (PET) for the early detection, staging and diagnosis of disease.
Kymberley R. Scroggie, Michael V. Perkins, Justin M. Chalker   +2 more
doaj   +1 more source

Investigation on the isotopic exchange radiofluorination of the pentafluorosulfanyl group.

Org Biomol Chem
Hiscocks H, Weerasinghe G, Huang W, Colasuonno F, Hill J, Ryan P, Johnston R, Brooks A, Scott PJH, Ung A, Lessio M, Hunter L, Pascali G.   +12 more
europepmc   +3 more sources

Novel Radioiodinated and Radiofluorinated Analogues of FT-2102 for SPECT or PET Imaging of mIDH1 Mutant Tumours

Molecules, 2022
Isocitrate dehydrogenases (IDHs) are metabolic enzymes commonly mutated in human cancers (glioma, acute myeloid leukaemia, chondrosarcoma, and intrahepatic cholangiocarcinoma).
Valérie Weber, Lucie Arnaud, Sladjana Dukic-Stefanovic, Barbara Wenzel, Valérie Roux, Jean-Michel Chezal, Thu-Hang Lai, Rodrigo Teodoro, Klaus Kopka, Elisabeth Miot-Noirault, Winnie Deuther-Conrad, Aurélie Maisonial-Besset   +11 more
doaj   +1 more source

Synthesis, in vitro and in vivo evaluation of 3β-[18F]fluorocholic acid for the detection of drug-induced cholestasis in mice [PDF]

, 2017
Introduction : Drug-induced cholestasis is a liver disorder that might be caused by interference of drugs with the hepatobiliary bile acid transporters. It is important to identify this interference early on in drug development.
De Lombaerde, Stef, De Vos, Filip, Devisscher, Lindsey, Kersemans, Ken, Neyt, Sara, Van Vlierberghe, Hans, Vanhove, Christian, Verhoeven, Jeroen   +7 more
core   +3 more sources

Recent Advances in Synthetic Methodologies to Form C-18F Bonds

Frontiers in Chemistry, 2022
Positron emission tomography (PET) is an important technique for the early diagnosis of disease. Due to the specific physical and chemical properties of Fluorine-18, this important isotope is widely used in PET for labelling and molecular imaging, and ...
Zhiyi Liu, Zhiyi Liu, Yijun Sun, Yijun Sun, Tianfei Liu, Tianfei Liu, Tianfei Liu   +6 more
doaj   +1 more source

Synthesis of 18F-labelled 2-fluoro-1,4-quinones using acetylhypofluorite [PDF]

, 1988
The fluorination of 1,4-benzo- and naphthoquinones using [18F]acetylhypofluorite is described.
Herscheid, Jacobus D.M., Verboom, Willem, Visser, Gerard W.M., Wedzinga, Rinny   +3 more
core   +3 more sources

Automated Solid-Phase Radiofluorination Using Polymer-Supported Phosphazenes

Molecules, 2013
The polymer supported phosphazene bases PS-P2tBu and the novel PS-P2PEG allowed for efficient extraction of [18F]F− from proton irradiated [18O]H2O and subsequent radiofluorination of a broad range of substrates directly on the resin.
Bente Mathiessen, Fedor Zhuravlev
doaj   +1 more source

Recent Advances in ¹⁸F-Labeled Amino Acids Synthesis and Application

Pharmaceutics, 2022
Radiolabeled amino acids are an important class of agents for positron emission tomography imaging that target amino acid transporters in many tumor types.
Chao Wang, Rong Lin, Shaobo Yao
doaj   +1 more source