Results 51 to 60 of about 3,410 (215)
A Convenient Route to New (Radio)Fluorinated and (Radio)Iodinated Cyclic Tyrosine Analogs
Pharmaceuticals, 2022 The use of radiolabeled non-natural amino acids can provide high contrast SPECT/PET metabolic imaging of solid tumors. Among them, radiohalogenated tyrosine analogs (i.e., [123I]IMT, [18F]FET, [18F]FDOPA, [123I]8-iodo-L-TIC(OH), etc.) are of particular ...
Maria Noelia Chao +11 more
doaj +1 more source
Methodological advancements in microfluidic and carbonylation PET radiochemistry [PDF]
, 2016 Along with the progress of PET as a powerful imaging tool in medicine, there has been increasing demand for new labeling methods. The main aim of this PhD dissertation was to develop novel labeling methodologies using the positron emitter carbon-11.
Dahl, Kenneth
core +1 more source
Production of 6-l-[18F]Fluoro-m-tyrosine in an Automated Synthesis Module for 11C-Labeling
Molecules, 2021 6-l-[18F]Fluoro-m-tyrosine (6-l-[18F]FMT) represents a valuable alternative to 6-l-[18F]FDOPA which is conventionally used for the diagnosis and staging of Parkinson’s disease.
Viktoriya V. Orlovskaya +6 more
doaj +1 more source
Nickel-Mediated Oxidative Fluorination for PET with Aqueous [\(^{18}F\)] Fluoride [PDF]
, 2012 A one-step oxidative fluorination for carbon–fluorine bond formation from well-defined nickel complexes with oxidant and aqueous fluoride is presented, which enables a straightforward and practical \(^{18}F\) late-stage fluorination of complex small ...
Hooker, Jacob M +2 more
core +1 more source
Synthesis of 2′‐[F‐18]fluoro‐2′‐DEOXY‐β‐D‐arabinofuranosyl nucleosides [PDF]
, 2001 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/91186/1/25804401320_ftp ...
Anderson, L. +3 more
core +1 more source
Molecular Imaging of Microglial Activation in Amyotrophic Lateral Sclerosis [PDF]
, 2012 There is growing evidence of activated microglia and inflammatory processes in the cerebral cortex in amyotrophic lateral sclerosis (ALS). Activated microglia is characterized by increased expression of the 18 kDa translocator protein (TSPO) in the brain
Arlicot, Nicolas +14 more
core +6 more sources
Angewandte Chemie, Volume 136, Issue 26, June 21, 2024.18F‐Fluoroheteroarenes find wide application as radiotracers for PET (positron emission tomography) imaging. Here, we present a deaminative radiosynthetic approach via pyridinium tetrafluoroborates that facilitates radiofluorination of 33 structurally diverse heteroarenes in up to 98 % RCY (radiochemical yield).
Joseph Ford +5 more
openalex +2 more sources
New AMD3100 derivatives for CXCR4 chemokine receptor targeted molecular imaging studies: synthesis, anti-HIV-1 evaluation and binding affinities [PDF]
, 2015 CXCR4 is a target of growing interest for the development of new therapeutic drugs and imaging agents as its role in multiple disease states has been demonstrated.
Archibald, Stephen J. +14 more
core +1 more source
Molecules, 2017 In a recent contribution of Scott et al., the substrate scope of Cu-mediated nucleophilic radiofluorination with [18F]KF for the preparation of 18F-labeled arenes was extended to aryl- and vinylstannanes.
Fadi Zarrad +4 more
doaj +1 more source
Pharmaceuticals, 2021 The incorporation of silicon fluoride acceptor (SiFA) moieties into a variety of molecules, such as peptides, proteins and biologically relevant small molecules, has improved the generation of 18F-radiopharmaceuticals for medical imaging.
Lexi Gower-Fry +12 more
doaj +1 more source