Results 71 to 80 of about 3,410 (215)

Double‐Click Strategy Combining CuAAC and (Thia‐) Diels‐Alder Reactions; Application Toward Peptide Labeling

Chemistry – A European Journal, Volume 31, Issue 41, July 22, 2025.
A double click‐strategy combining copper‐catalyzed azide‐alkyne cycloaddition with (thia‐)Diels‐Alder reactions involving a reactive s‐cis‐constrained diene is reported. Three different one‐pot protocols (i.e., sequential or three‐component reactions) are proposed and offer valuable guidance for future applications.
Timothé Maujean, Camille Van Wesemael, Laurine Tual, Valentine Le Berruyer, Blanca Rodriguez‐Noguer, Nicolas Girard, Dominique Bonnet, Mihaela Gulea   +7 more
wiley   +1 more source

Synthesis of [ 18 F]fluoroethoxy‐benzovesamicol, a radiotracer for cholinergic neurons [PDF]

, 1993
Full experimental details are given for the preparation of [ 18 F]fluoroethoxy‐benzovesamicol, (−)‐( 2R, 3R )‐ trans ‐2‐hydroxy‐3‐(4‐phenylpiperidino)‐5‐(2‐[ 18 F]fluoroethoxy)‐1,2,3,4‐tetralin, a new fluorine‐18 labeled cholinergic neuron mapping agent ...
Altar, Block, Block, Chi, Dale, Efange, French, Hicks, Jerabek, Jung, Keisewetter, Kiesewetter, Kilbourn, Lemaire, Marien, Marshall, Moerlein, Mulholland, Mulholland, Mulholland, Mulholland, Mulholland, Mulholland, Plenevaux, Rogers, Rogers, Rogers, Rogers, Satymurthy, Shuie, Suehiro, Widen   +31 more
core   +1 more source

The 18F‐Difluoromethyl Group: Challenges, Impact and Outlook

Angewandte Chemie, Volume 136, Issue 26, June 21, 2024.
This Minireview summarises the progress radiochemists have made to access the difluoromethyl group in radiolabelled form. Particular attention is given to challenges they have faced, as well as the strategies employed to access this new radiochemical space.
Joseph Ford, Sebastiano Ortalli, Véronique Gouverneur   +2 more
wiley   +2 more sources

An efficient, versatile procedure for the [18F]-radiofluorination of base-sensitive tracers with high radiochemical conversion

Nuclear Medicine and Biology
Alexandros Ch. Pappas, Stefan Milton, Jeroen Goos, Niki Constantinou, Staffan Holmin   +4 more
openalex   +2 more sources

Untersuchungen zur trägerarmen Radiofluorierung nicht-aktivierter Aromaten mit n.c.a. [18F]Fluorid [PDF]

, 2011
In vivo imaging with positron emission tomography generally demands radiotracers with a high specific activity. In case of fluorine-18 the required no-carrier-added (n.c.a.) starting material is only available in form of fluoride. This and the short half-
Cardinale, Jens
core  

Pioneering Metal‐Free Late‐Stage C−H Functionalization Using Acridinium Salt Photocatalysis

Chemistry – A European Journal, Volume 30, Issue 67, December 2, 2024.
Organic dyes are powerful photocatalysts in organic transformations due to their availability, adaptable absorption, and diverse structures. Acridinium‐based organo‐photocatalysts, notable for visible light responsiveness, efficiently functionalize inert C−H bonds under mild conditions without transition metals.
Shyamal Kanti Bera, Andrea Porcheddu
wiley   +1 more source

Использование соединений поливалентного иода в получении [18F]фторсодержащих трейсеров для позитронной эмиссионной томографии [PDF]

, 2011
Впервые проведен анализ научной литературы по использованию соединений поливалентного иода в синтезе прекурсоров - иодониевых солей для введения атома [18F]фтора в структуру органических ...
Дрыгунова, Лариса Александровна, Ларькина, Мария Сергеевна, Юсубов, Мехман Сулейман-оглы (Сулейманович)   +2 more
core   +2 more sources

Development new radiopharmaceutical based on 5-thio-d- glucose labeled technetium-99m [PDF]

, 2016
The article considers the obtaining and possibility of using 5-thio-D-glucose labeled technetium-99m for the diagnosis of malignant tumors by single photon emission computed tomography.
Ilina, Elena Sergeevna, Larionova, Lyudmila Aleksandrovna, Nesterov, Evgeny Alexandrovich, Rogov, Alexander Sergeyevich, Sadkin, Vladimir Leonidovich, Skuridin, Viktor Sergeyevich, Stasyuk (Stasiuk), Elena Sergeyevna, Varlamova, Natalya Valeryevna, Zelchan, R.   +8 more
core   +1 more source

Synthesis and properties of metal trifluoride complexes with amide-functionalised tacn macrocycles and radiofluorination of [GaF3(L1)] by 18F/19F isotopic exchange.

Dalton Transactions
Three amide-functionalised tacn macrocyclic derivatives (tacn = 1,4,7-triazacyclononane) are reported, two tris-amide derivatives, L1 containing three -CH2C(O)NHPh pendant arms, L2 containing three -CH2CH2C(O)NHiPr pendant arms, and one mono-amide, L3 ...
Charley O'Callaghan, V. Greenacre, R. King, Julian Grigg, J. Herniman, G. McRobbie, Gillian Reid   +6 more
semanticscholar   +1 more source

Nucleophilic Radiofluorination Using Tri-tert-Butanol Ammonium as a Bifunctional Organocatalyst: Mechanism and Energetics

Molecules, 2022
We present a quantum chemical analysis of the 18F-fluorination of 1,3-ditosylpropane, promoted by a quaternary ammonium salt (tri-(tert-butanol)-methylammonium iodide (TBMA-I) with moderate to good radiochemical yields (RCYs), experimentally observed by ...
Young-Ho Oh, Sandip S. Shinde, Sungyul Lee   +2 more
doaj   +1 more source