Results 1 to 10 of about 88,244 (379)

Radiolabeling of Nanomaterials: Advantages and Challenges

Frontiers in Toxicology, 2021
Quantifying the distribution of nanomaterials in complex samples is of great significance to the toxicological research of nanomaterials as well as their clinical applications.
Wanqin Dai, Wanqin Dai, Wanqin Dai, Junzhe Zhang, Junzhe Zhang, Yun Wang, Yun Wang, Yun Wang, Chunlei Jiao, Chunlei Jiao, Chunlei Jiao, Zhuda Song, Zhuda Song, Zhuda Song, Yuhui Ma, Yuhui Ma, Yayun Ding, Yayun Ding, Zhiyong Zhang, Zhiyong Zhang, Zhiyong Zhang, Xiao He, Xiao He   +22 more
doaj   +2 more sources

Radiolabeling of functional oligonucleotides for molecular imaging

Frontiers in Bioengineering and Biotechnology, 2022
Molecular imaging has greatly advanced basic biology and translational medicine through visualization and quantification of molecular events in a cellular context and living organisms.
Dunfang Liu, Dunfang Liu, Qian Xia, Qian Xia, Ding Ding, Weihong Tan, Weihong Tan, Weihong Tan   +7 more
doaj   +2 more sources

Centrifuge-free cell radiolabeling using acoustophoresis [PDF]

Scientific Reports
Tracking ex vivo radiolabeled cells using radionuclide imaging such as positron emission tomography is an emerging method for evaluating cell-based therapies.
Stephen S. Adler, Emma Stevenson, Julia Alsveds, Peter L. Choyke, Noriko Sato   +4 more
doaj   +2 more sources

PET and SPECT Tracer Development via Copper-Mediated Radiohalogenation of Divergent and Stable Aryl-Boronic Esters [PDF]

Pharmaceutics
Background/Objectives: Positron emission tomography (PET) and single-photon emission computed tomography (SPECT) are highly sensitive clinical imaging modalities, frequently employed in conjunction with magnetic resonance imaging (MRI) or computed ...
Austin Craig, Frederik J. Sachse, Markus Laube, Florian Brandt, Klaus Kopka, Sven Stadlbauer   +5 more
doaj   +2 more sources

Comparative Study of Two Oxidizing Agents, Chloramine T and Iodo-Gen^®, for the Radiolabeling of β-CIT with Iodine-131: Relevance for Parkinson’s Disease

Pharmaceuticals, 2019
Parkinson’s disease (PD) is a neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta, leading to alteration of the integrity of dopaminergic transporters (DATs).
Ana Claudia R. Durante, Danielle V. Sobral, Ana Claudia C. Miranda, Érika V. de Almeida, Leonardo L. Fuscaldi, Marycel R. F. F. de Barboza, Luciana Malavolta   +6 more
doaj   +2 more sources

Radiolabeled Bombesin Analogs [PDF]

Cancers, 2021
The gastrin-releasing peptide receptor (GRPR) is expressed in high numbers in a variety of human tumors, including the frequently occurring prostate and breast cancers, and therefore provides the rationale for directing diagnostic or therapeutic radionuclides on cancer lesions after administration of anti-GRPR peptide analogs.
Rosalba Mansi, Berthold A. Nock, Simone U. Dalm, Martijn B. Busstra, Wytske M. van Weerden, Theodosia Maina   +5 more
openaire   +3 more sources

Radiolabeled PSMA Inhibitors [PDF]

Cancers, 2021
PSMA has shown to be a promising target for diagnosis and therapy (theranostics) of prostate cancer. We have reviewed developments in the field of radio- and fluorescence-guided surgery and targeted photodynamic therapy as well as multitargeting PSMA inhibitors also addressing albumin, GRPr and integrin αvβ3.
Oliver C. Neels, Klaus Kopka, Christos Liolios, Ali Afshar-Oromieh   +3 more
openaire   +4 more sources

Direct Cell Radiolabeling for in Vivo Cell Tracking with PET and SPECT Imaging

Chemical Reviews, 2022
The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical application in a rational manner depends on reliable, clinically applicable methods for determining the fate and trafficking of therapeutic cells in vivo using ...
P. Gawne, F. Man, P. Blower, Rafael T. M. de Rosales   +3 more
semanticscholar   +1 more source

Radiolabeling of gamma-irradiated rosmarinic acid by 67Gallium [PDF]

مجله علوم و فنون هسته‌ای, 2023
Rosemary plant extract as a natural anti-oxidant is 4 times stronger than synthetic anti-oxidant like BHT and BHA. For this reason, it has been under attention not only for its anti-oxidant properties rather for its anti-inflammatory, anti-tumor, anti ...
N. Damavandi Kamali, S. Rajabifar, M. Heidarieh   +2 more
doaj   +1 more source

Optimized production, purification, and radiolabeling of the 203Pb/212Pb theranostic pair for nuclear medicine

Scientific Reports, 2023
TRIUMF is one of the only laboratories in the world able to produce both lead-203 (^203Pb, t_1/2 = 51.9 h) and ^212Pb (t_1/2 = 10.6 h) onsite via its 13 and 500 MeV cyclotrons, respectively.
Brooke L McNeil, Simona Mastroianni, S. McNeil, S. Zeisler, J. Kumlin, Sogol Borjian, Anthony W. McDonagh, M. Cross, P. Schaffer, C. Ramogida   +9 more
semanticscholar   +1 more source