Results 111 to 120 of about 33,330 (276)

177Lu‐labeled amidoxime‐functionalized biodegradable microspheres for transarterial radioembolization of hepatocellular carcinoma

open access: yesPrecision Radiation Oncology, EarlyView.
Scheme 1. Schematic illustration of the synthesis and therapeutic evaluation of PLA‐g‐PAO microspheres (PLA‐g‐PAO‐Ms). Monodisperse PLA microspheres (PLA‐Ms) were initially fabricated via microfluidic technology. Surface grafting of acrylonitrile monomers was subsequently achieved through radiation‐induced graft polymerization, followed by ...
Xingliang Liu   +7 more
wiley   +1 more source

Expression and radiolabeling of recombinant proteins containing a phosphorylation motif

open access: yes, 1996
Radiolabeled proteins are useful in basic and clinical research. Current methods available for radiolabeling proteins involve chemical derivatization, resulting in multiple additions of radionuclides at random sites.
Mohanraj, D   +2 more
core   +1 more source

Sodium Ions Affect GPR17 Conformational States and Functionality

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Sodium is an allosteric modulator of several class‐A GPCR regulating active versus inactive conformation state and may be a critical issue for the optimization of crystallization procedures. Herein, the role of Na+ in the regulation of GPR17 conformational states was studied through MD simulations of GPR17 wild‐type and mutated on two ...
Luca Palazzolo   +6 more
wiley   +1 more source

Development of a Thin Layer Chromatography method to determine the radiolabeling stability of PCL-PEO micelles radiolabeled with ¹⁷⁷Lu

open access: yes, 2021
Polymeric micelles have a promising future in the treatment of cancer patients, and particularly as carriers in chemotherapy. The effectiveness of the micelles can be determined when their fate in vivo is known. Radiolabeling the micelles with diagnostic
Kerstjens, Willem (author)
core  

Effects of medicinal plants on radiolabeling and biodistribution of diagnostic radiopharmaceuticals: A systematic review [PDF]

open access: yes, 2019
Radiopharmaceuticals are drugs that contain radioisotopes used for diagnostic and therapeutic purposes. There are evidences that medicinal herbs and their constituents can modify the radiolabeling, biodistribution, and pharmacokinetics of ...
Yang, Qian   +2 more
core   +1 more source

Identifying resistance‐conferring cytochrome P450s in weeds: experimental strategies and practical considerations

open access: yesPest Management Science, EarlyView.
Identifying resistance‐conferring cytochrome P450s requires integrating weed characterization, gene discovery and functional validation. No single approach is sufficient to distinguish causal resistance genes from herbicide‐metabolizing enzymes. Abstract Cytochrome P450 monooxygenases (P450s) play a pivotal role in metabolic herbicide resistance, yet ...
Satoshi Iwakami, Takuya Yamaguchi
wiley   +1 more source

A new method for radiolabeling of human immunoglobulin-G and its biological evaluation

open access: yesJournal of Pharmacy and Bioallied Sciences, 2012
Background: Radiolabeled human Immunoglobulin-G (hIgG) has demonstrated its utility in inflammation and infection imaging. However, the present method of radiolabeling hIgG is time-consuming and complex.
Thakuri Singh   +6 more
doaj   +1 more source

Absorption and translocation of 14C‐propiconazole associated with two adjuvants in young coffee plants

open access: yesPest Management Science, EarlyView.
Experimental workflow evaluating 14C‐propiconazole absorption and translocation in Coffea arabica with two biodegradable adjuvants, quantified at six post‐application time points using radioscanner and liquid scintillation spectrometry. Abstract BACKGROUND This study evaluated the absorption, translocation and distribution of 14C‐propiconazole applied ...
Valéria de Souza Ivo   +4 more
wiley   +1 more source

X-ray Structures of Succinimidyl Halobenzoates

open access: yesCrystals, 2017
The crystal and molecular structures of five succinimidyl halobenzoates are reported. Corresponding derivatives with the respective halo-radionuclide (18F, 76Br, 123I/124I/125I/131I) were prepared and used for the radiolabeling of biologically active ...
Constantin Mamat   +2 more
doaj   +1 more source

89Zr-Df-CD45 radiolabeling of hPBSC.

open access: yes, 2013
hPBSC were labeled with 0, 20, 40, 80, or 160 µCi/mL of 89Zr-Df-CD45. No significant changes in cell viability were observed with increasing concentrations. However, a greater degree of radiolabeling was observed with 80 and 160 µCi/mL of 89Zr-Df-CD45. A
C. Chang I. Lee (414865)   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy