Understanding the in vivo Uptake Kinetics of a Phosphatidylethanolamine-binding Agent \u3csup\u3e99m\u3c/sup\u3eTc-Duramycin [PDF]
, 2012 Introduction 99mTc-Duramycin is a peptide-based molecular probe that binds specifically to phosphatidylethanolamine (PE). The goal was to characterize the kinetics of molecular interactions between 99mTc-Duramycin and the target tissue.
Audi, Said H. +6 more
core +1 more source
Molecular Imaging of Vulnerable Coronary Plaque with Radiolabeled Somatostatin Receptors (SSTR) [PDF]
, 2021 Luz Kelly Anzola +4 more
openalex +1 more source
X-ray Structures of Succinimidyl Halobenzoates
Crystals, 2017 The crystal and molecular structures of five succinimidyl halobenzoates are reported. Corresponding derivatives with the respective halo-radionuclide (18F, 76Br, 123I/124I/125I/131I) were prepared and used for the radiolabeling of biologically active ...
Constantin Mamat +2 more
doaj +1 more source
89Zr-Radiolabeled Trastuzumab Imaging in Orthotopic and Metastatic Breast Tumors [PDF]
, 2012 The human epidermal growth factor receptor 2 (HER2/neu) is overexpressed in 20-30% of breast cancers and is associated with tumor growth, angiogenesis, and development of distant metastases.
Chang, Albert J. +5 more
core +3 more sources
New Frontiers in Cancer Imaging and Therapy Based on Radiolabeled Fibroblast Activation Protein Inhibitors: A Rational Review and Current Progress [PDF]
, 2021 Surachet Imlimthan +6 more
openalex +1 more source
Method Overview for Discovering ATE1 Substrates and their Arginylation Sites
ChemBioChem, EarlyView.Arginylation is a decades‐old post‐translational modification but is inherently difficult to study. A plurality of methods have been developed and deployed to uncover the biology and substrates of this modification. This review covers the history, major advancements, and substrates discovered over the course of six decades.
Richard M. Searfoss +2 more
wiley +1 more source
Radiolabeled EGFR Tyrosine Kinase for the Detection of Dual Mutations EGFR L858R/T790M in NSCLC
, 2023 openalex +1 more source
Bioorthogonal Chemistry in Biomolecule Quantification: A Review of Reactions and Strategies
Chemistry – A European Journal, EarlyView.This review summarizes the application of catalyst‐free bioorthogonal reactions: Staudinger ligation, strain promoted azide alkyne cycloaddition, inverse electron‐demand Diels–Alder, and 2‐cyanobenzothiazole cysteine condensation in the semi‐quantitative and quantitative analysis of biomolecules.
Mingze Yang, Shiqi Wang
wiley +1 more source
Characterization of avirulent mutant Legionella pneumophila that survive but do not multiply within human monocytes. [PDF]
, 1987 Legionella pneumophila, the causative agent of Legionnaires' disease, is a Gram-negative bacterium and a facultative intracellular parasite that multiplies in human monocytes and alveolar macrophages. In this paper, mutants of L.
Horwitz, MA
core
Chemistry of Materials, 2017 Designing a nanomaterials platform with high target-to-background ratios has long been one of the major challenges in the field of nanomedicine. Here, we introduce a "target-or-clear" multifunctional nanoparticle platform that demonstrates high tumor ...
Feng Chen +8 more
semanticscholar +1 more source