Synthesis and Evaluation of Fluorine-18-Labeled L-Rhamnose Derivatives
Molecules, 2023 The use of radiolabeled glucose for PET imaging resulted in the most commonly used tracer in the clinic, 2-deoxy-2-[18F]fluoroglucose (FDG). More recently, other radiolabeled sugars have been reported for various applications, including imaging tumors ...
Xiang Zhang +9 more
doaj +1 more source
Effect of an extract of Centella asiatica on the biodistribution of sodium pertechnetate (Na99mTcO4) and on the fixation of radioactivity on blood constituents [PDF]
, 2008 This study evaluates the effects of an acute treatment with a Centella asiatica (CA) extract on the biodistribution of the radiopharmaceutical Na99mTcO4 and on the fixation of technetium-99m on blood constituents. Wistar rats were treated with CA extract
Adenilson de Souza da Fonseca +22 more
core +4 more sources
Radiolabeling Strategies of Nanobodies for Imaging Applications
Diagnostics, 2021 Nanobodies are small recombinant antigen-binding fragments derived from camelid heavy-chain only antibodies. Due to their compact structure, pharmacokinetics of nanobodies are favorable compared to full-size antibodies, allowing rapid accumulation to ...
Jim Küppers +4 more
semanticscholar +1 more source
τBu₂SiF-Derivatized D₂-Receptor Ligands: The First SiFA-Containing Small Molecule Radiotracers for Target-Specific PET-Imaging [PDF]
, 2011 The synthesis, radiolabeling and in vitro evaluation of new silicon-fluoride acceptor (SiFA) derivatized D-2-receptor ligands is reported. The SiFA-technology simplifies the introduction of fluorine-18 into target specific biomolecules for Positron ...
Bartenstein, Peter +10 more
core +2 more sources
Assessment of the tissue distribution of transplanted human endothelial progenitor cells by radioactive labeling [PDF]
, 2003 Background— Transplantation of endothelial progenitor cells (EPCs) improves vascularization and left ventricular function after experimental myocardial ischemia.
Aicher, A +9 more
core +1 more source
Pharmaceutics, 2020 Actinium-225 (225Ac) is receiving increased attention for its application in targeted radionuclide therapy, due to the short range of its emitted alpha particles in conjunction with their high linear energy transfer, which lead to the eradication of ...
Evangelia-Alexandra Salvanou +11 more
doaj +1 more source
Preparation and biological studies of 68Ga-DOTA-alendronate [PDF]
Asia Oceania Journal of Nuclear Medicine and Biology, 2016 Objective(s): In line with previous research on the development of conjugated bisphosphonate ligands as new bone-avid agents, in this study, DOTA conjugated alendronate (DOTA-ALN) was synthesized and evaluated after labeling with gallium-68 (68Ga ...
Ashraf Fakhari +4 more
doaj +1 more source
Melanocortin 1 receptor targeted imaging of melanoma with gold nanocages and positron emission tomography [PDF]
, 2018 Purpose: Melanoma is a lethal skin cancer with unmet clinical needs for targeted imaging and therapy. Nanoscale materials conjugated with targeting components have shown great potential to improve tumor delivery efficiency while minimizing undesirable ...
Black, Kvar +8 more
core +2 more sources
In vivo imaging of pyrrole-imidazole polyamides with positron emission tomography [PDF]
, 2008 The biodistribution profiles in mice of two pyrrole-imidazole polyamides were determined by PET. Pyrrole-imidazole polyamides are a class of small molecules that can be programmed to bind a broad repertoire of DNA sequences, disrupt transcription factor ...
Bergstr m +26 more
core +3 more sources
Molecules, 2020 Concern about environmental exposure to hazardous substances has grown over the past several decades, because these substances have adverse effects on human health.
Jae Young Lee +5 more
doaj +1 more source