Results 41 to 50 of about 87,481 (331)

Positron emission tomography imaging of endometrial cancer using engineered anti-EMP2 antibody fragments. [PDF]

, 2012
PurposeAs imaging of the cell surface tetraspan protein epithelial membrane protein-2 (EMP2) expression in malignant tumors may provide important prognostic and predictive diagnostic information, the goal of this study is to determine if antibody ...
Braun, Jonathan, Brewer, Sarah, Fu, Maoyong, Gordon, Lynn K, Olafsen, Tove, Said, Jonathan, Wadehra, Madhuri, Wu, Anna M   +7 more
core   +3 more sources

High-performance liquid chromatography as a technique to measure the competitive adsorption of plasma proteins onto latices [PDF]

, 1984
Isotherms of human serum albumin (HSA), human immunoglobulin G (HIgG), and human fibrinogen (HFb) onto a polystyrene (PS)-latex were determined by depletion of protein in the solution, which was either followed by radioactivity measurements or by UV ...
Bargeman, Dick, Bergveld, Piet, Feijen, Jan, Lensen, Henny G.W., Smolders, Cees A.   +4 more
core   +8 more sources

Functional Characterization of the Eukaryotic Cysteine Desulfurase Nfs1p from Saccharomyces cerevisiae [PDF]

, 2004
Previous studies have indicated that the essential protein Nfs1 performs a crucial role in cellular iron-sulfur (Fe/S) protein maturation. The protein is located predominantly in mitochondria, yet low amounts are present in cytosol and nucleus.
Balk, Balk, Cupp-Vickery, Diekert, Dutkiewicz, Floss, Frazzon, Frazzon, Garland, Gerber, Gerber, Gietz, Gyula Kispal, Harlow, Hoff, Janneke Balk, Jaschkowitz, Jens T. Kaiser, Kaiser, Kambampati, Kambampati, Katalin Sipos, Kaut, Kim, Kispal, Knight, Knight, Knox, Kolman, Land, Lange, Lange, Lauhon, Leibrecht, Leipuviene, Li, Lill, Matthies, Meyer, Mihara, Mühlenhoff, Mühlenhoff, Mühlenhoff, Nachin, Nadine Richhardt, Nakai, Nakai, Nett, Nilsson, Outten, Papenbrock, Pierrel, Roland Lill, Roy, Sambrook, Schilke, Schwartz, Sherman, Silberg, Sipos, Skovran, Stein, Strain, Takahashi, Tong, Tong, Ulrich Mühlenhoff, Ungermann, Voisine, Wang, Yuvaniyama, Zheng, Zheng, Zheng   +73 more
core   +3 more sources

In Vivo Imaging of Transplanted Islets with ^(64)Cu-DO3A-VS-Cys^(40)-Exendin-4 by Targeting GLP-1 Receptor [PDF]

, 2011
Glucagon-like peptide 1 receptor (GLP-1R) is highly expressed in pancreatic islets, especially on β-cells. Therefore, a properly labeled ligand that binds to GLP-1R could be used for in vivo pancreatic islet imaging.
Bading, James R., Colcher, David, Conti, Peter E., Fraser, Scott E., Ishiyama, Kohei, Kandeel, Fouad, Li, Lin, Li, Zibo, Nair, Indu, Shively, John E., Todorov, Ivan, Wu, Zhanhong   +11 more
core   +2 more sources

From Host to Phage Metabolism: Hot Tales of Phage T4’s Takeover of E. coli

Viruses, 2018
The mechanisms by which bacteriophage T4 converts the metabolism of its E. coli host to one dedicated to progeny phage production was the subject of decades of intense research in many labs from the 1950s through the 1980s.
Elizabeth Kutter, Daniel Bryan, Georgia Ray, Erin Brewster, Bob Blasdel, Burton Guttman   +5 more
doaj   +1 more source

Development of PDT/PET theranostics: synthesis and biological evaluation of an ¹⁸F-radiolabeled water soluble porphyrin [PDF]

, 2015
Synthesis of the first water-soluble porphyrin radiolabeled with fluorine-18 is described: a new molecular theranostic agent which integrates the therapeutic selectivity of photodynamic therapy (PDT) with the imaging efficacy of positron emission ...
Allott, Louis, Archibald, Stephen J., Boyle, Ross W., Bryden, Francesca, Cawthorne, Chris, Domarkas, Juozas, Entract, Guy M., Savoie, Huguette   +7 more
core   +1 more source

Analysis of iodinated quorum sensing peptides by LC-UV/ESI ion trap mass spectrometry [PDF]

, 2018
Five different quorum sensing peptides (QSP) were iodinated using different iodination techniques. These iodinated peptides were analyzed using a C-18 reversed phase HPLC system, applying a linear gradient of water and acetonitrile containing 0.1% (m/v ...
De Spiegeleer, Bart, Debunne, Nathan, Janssens, Yorick, Peremans, Kathelijne, Verbeke, Frederick, Wynendaele, Evelien   +5 more
core   +2 more sources

A Systematic Evaluation of Antibody Modification and 89Zr-Radiolabeling for Optimized Immuno-PET.

Bioconjugate chemistry, 2020
Immuno-PET using desferrioxamine (DFO)-conjugated zirconium-89 ([89Zr]Zr4+)-labeled antibodies is a powerful tool used for preclinical and clinical molecular imaging. However, a comprehensive study evaluating the variables involved in DFO-conjugation and
Sai Kiran Sharma, Jonathan M. Glaser, K. J. Edwards, Elaheh Khozeimeh Sarbisheh, A. Salih, Jason S. Lewis, E. Price   +6 more
semanticscholar   +1 more source

First-in-man evaluation of 124I-PGN650: A PET tracer for detecting phosphatidylserine as a biomarker of the solid tumor microenvironment [PDF]

, 2017
Purpose: PGN650 is a F(ab′) 2 antibody fragment that targets phosphatidylserine (PS), a marker normally absent that becomes exposed on tumor cells and tumor vasculature in response to oxidative stress and increases in response to therapy.
Dehdashti, Farrokh, Freimark, Bruce D, Frye, Jennifer, Frye, Sarah, Laforest, Richard, Liu, Yongjian, Luehmann, Hannah, Shan, Joseph S, Siegel, Barry A, Sultan, Deborah   +9 more
core   +2 more sources

Production, purification, and radiolabeling of the 203Pb/212Pb theranostic pair

EJNMMI Radiopharmacy and Chemistry, 2020
Background Lead-212 ( 212 Pb, t 1/2  = 10.6 h) and lead-203 ( 203 Pb, t 1/2  = 51.9 h) are an element-equivalent, or a matched theranostic radioisotope pair that show great potential for application in targeted radionuclide therapy (TRT) and single ...
Brooke L McNeil, A. Robertson, Winnie Fu, Hua Yang, C. Hoehr, C. Ramogida, P. Schaffer   +6 more
semanticscholar   +1 more source