Results 51 to 60 of about 88,244 (379)
From Host to Phage Metabolism: Hot Tales of Phage T4’s Takeover of E. coli
Viruses, 2018 The mechanisms by which bacteriophage T4 converts the metabolism of its E. coli host to one dedicated to progeny phage production was the subject of decades of intense research in many labs from the 1950s through the 1980s.
Elizabeth Kutter +5 more
doaj +1 more source
The influence of generator eluate in radiolabeling PSMA-11 kit with 68Ga
Brazilian Journal of Radiation Sciences, 2021 Gaining prominence in clinical practice, the 68Ga, positron emitter radionuclide easily obtained by 68Ge/68Ga generator elution, has shown potential and excellent quality on radiolabeling of peptide for use in positron emission tomography (PET), in ...
Bianca Franchesqueti Vivaldini +1 more
doaj +1 more source
Radiolabeling of Theranostic Nanosystems [PDF]
, 2021 In the recent years, progress in nanotechnology has significantly contributed to the development of novel pharmaceutical formulations to overcome the drawbacks of conventional treatments and improve the therapeutic outcome in many diseases, especially cancer.
Das, Sudeep +3 more
openaire +5 more sources
Isotopic Radiolabeling of the Antiretroviral Drug [18F]Dolutegravir for Pharmacokinetic PET Imaging
Pharmaceuticals, 2022 Deciphering the drug/virus/host interactions at infected cell reservoirs is a key leading to HIV-1 remission for which positron emission tomography (PET) imaging using radiolabeled antiretroviral (ARV) drugs is a powerful asset. Dolutegravir (DTG) is one
Marion Tisseraud +9 more
doaj +1 more source
Production, purification, and radiolabeling of the 203Pb/212Pb theranostic pair
EJNMMI Radiopharmacy and Chemistry, 2020 Background Lead-212 ( 212 Pb, t 1/2 = 10.6 h) and lead-203 ( 203 Pb, t 1/2 = 51.9 h) are an element-equivalent, or a matched theranostic radioisotope pair that show great potential for application in targeted radionuclide therapy (TRT) and single ...
Brooke L McNeil +6 more
semanticscholar +1 more source
First-in-man evaluation of 124I-PGN650: A PET tracer for detecting phosphatidylserine as a biomarker of the solid tumor microenvironment [PDF]
, 2017 Purpose: PGN650 is a F(ab′) 2 antibody fragment that targets phosphatidylserine (PS), a marker normally absent that becomes exposed on tumor cells and tumor vasculature in response to oxidative stress and increases in response to therapy.
Dehdashti, Farrokh +9 more
core +2 more sources
Chemically Modified Extracellular Vesicles and Applications in Radiolabeling and Drug Delivery
Pharmaceutics, 2022 Extracellular vesicles (EVs) have been exploited as bio-inspired drug delivery systems (DDS) in the biomedical field. EVs have more advantages than synthetic nanoparticles: they are naturally equipped to cross extra- and intra-cellular barriers ...
Elisa-Racky N’Diaye +3 more
doaj +1 more source
Pharmaceuticals, 2020 Barium-131 is a single photon emission computed tomography (SPECT)-compatible radionuclide for nuclear medicine and a promising diagnostic match for radium-223/-224.
F. Reissig +8 more
semanticscholar +1 more source
Analysis of iodinated quorum sensing peptides by LC-UV/ESI ion trap mass spectrometry [PDF]
, 2018 Five different quorum sensing peptides (QSP) were iodinated using different iodination techniques. These iodinated peptides were analyzed using a C-18 reversed phase HPLC system, applying a linear gradient of water and acetonitrile containing 0.1% (m/v ...
De Spiegeleer, Bart +5 more
core +2 more sources
EJNMMI Radiopharmacy and Chemistry, 2020 Background The AAZTA chelator and in particular its bifunctional derivative AAZTA 5 was recently investigated to demonstrate unique capabilities to complex diagnostic and therapeutic trivalent radiometals under mild conditions.
J. Sinnes +5 more
semanticscholar +1 more source