Results 111 to 120 of about 26,475 (236)
PLoS Computational Biology, 2019 Radiation therapy is an important and effective treatment option for prostate cancer, but high-risk patients are prone to relapse due to radioresistance of cancer cells.
Michael Seifert +5 more
doaj +1 more source
Cancer Science, EarlyView.DNA hypermethylation causally correlates with better treatment response of HPV(+) HNSCC, and its chemosensitivity might be enhanced by silencing of methylation target genes. Silencing of ROBO1 enhances, and its overexpression reduces, CDDP chemosensitivity, and epigenetic or ROBO1‐targeted interventions may improve therapeutic outcomes in resistant HPV(
Kenta Saeda +11 more
wiley +1 more source
Cancer Science, EarlyView.tRNA‐derived small RNAs (tsRNAs) function in digestive cancers across three scales: intracellular translational and metabolic control, extracellular vesicle–mediated immune remodeling, and systemic and host–microbe communication. This review organizes these mechanisms by evidence strength, from well‐established intracellular roles to emerging ...
Wang Xitan, Li Han
wiley +1 more source
Induction of radioresistance in Escherichia coli
Biophysical Journal, 1975 The effect of prior treatment by inducing agents on the radioresistance of cells of Escherichia coli has been studied. In order to separate the induction process from the radiation-damage process, cells were first treated with inducing agents such as ultraviolet light, ionizing radiation, or nalidixic acid, allowed to become induced by incubation for ...
Pollard, E.C., Achey, P.M.
openaire +2 more sources
Molecular basis of radioresistance [PDF]
European Journal of Cancer, 1995 P A, Coucke, N E, Crompton
openaire +2 more sources
Hypoxia in drug resistance and radioresistance
[[abstract]]Tumors mostly experience hypoxia or hypoxic stress as they progress, especially for tumor cells that are located far from the functional blood vessels. Pathologically. tumor hypoxia is known to play an important role in tumor progression, and
Chang, KY;Lin, IL;Cheung, CHA
core +1 more source
Advances in Radiotherapy for Neoadjuvant Therapy of Stage III Non‐Small Cell Lung Cancer
Cancer Science, EarlyView.This review summarizes three neoadjuvant radiotherapy techniques for stage III NSCLC, highlighting SFRT's low‐toxicity dual immune‐tumor control benefits and radioimmunotherapy's superior pathological response to guide precise multimodal treatment. ABSTRACT This review aims to systematically summarize the mechanisms of action, clinical evolution, and ...
Qinrong Mao +5 more
wiley +1 more source
The FEBS Journal, EarlyView.RNA and DNA viruses can manipulate host cell death through various mechanisms. RNA viruses (H1N1, SARS‐CoV‐2) induce acute apoptosis, necroptosis, and pyroptosis to promote rapid viral transmission and epithelial barrier damage. In contrast, DNA viruses (HSV‐1, EBV) regulate these mechanisms to sustain a lytic‐latency cycle, evade immune response and ...
Panagiotis Keramidas +4 more
wiley +1 more source
Mapping the Bioenergetic Landscape of Oral Cancer Stem Cells: A Systematic Review
Oral Diseases, EarlyView.ABSTRACT Objectives Oral squamous cell carcinoma (OSSC) remains highly lethal, with resistance largely driven by cancer stem cells (CSCs). Mitochondrial reprogramming supports CSC redox control, self‐renewal, and survival. This systematic review aimed to synthesize mitochondrial mechanisms sustaining CSCs in OSCC and evaluate their therapeutic ...
Rodrigo Elísio de Sá +6 more
wiley +1 more source
Veterinary and Comparative Oncology, EarlyView.ABSTRACT Although osteosarcoma is the most common primary bone tumour in dogs, involvement of the pelvic bones is rare. The aim of the present study was to describe clinical presentation, identify possible prognostic factors, and evaluate outcomes in dogs diagnosed with pelvic osteosarcoma.
Csilla Fejös +15 more
wiley +1 more source