Results 71 to 80 of about 18,687 (179)

Advancements in Inorganic Chiral Nanomaterials for Anti‐Tumor Immunotherapy

Cancer Science, EarlyView.
Schematic illustration of how inorganic chiral nanomaterials enhance immune activation to promote tumor cell elimination through targeted delivery, immunogenic cell death, and immune microenvironment modulation. ABSTRACT While the past decade has witnessed unprecedented technological advancements, cancer remains a major health threat, with conventional
Siyu Chen, Qian Tang, Xiqian Chen, Yinghao Liang, Jin Qiu, Yongmei Liao, Changqiang Li, Hongru Yu, Fang Xie, Zongjunlin Liu   +9 more
wiley   +1 more source

Brentuximab vedotin and radiotherapy for CD30‐positive cutaneous T‐cell lymphoma – a retrospective multicenter analysis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives While brentuximab vedotin (BV) and radiotherapy (RTx) are established treatment options for CD30‐positive cutaneous T‐cell lymphoma (CTCL), data on their simultaneous or sequential use regarding efficacy and tolerability remain scarce.
Patrick Schummer, Caroline Glatzel, Philipp Schrüfer, Ingulf Lawrenz, Gabor Dobos, Ulrike Wehkamp, Svea Hüning, René Stranzenbach, Jan P. Nicolay, Matthias Goebeler, Marion Wobser   +10 more
wiley   +1 more source

An update on the landscape of collagen bioactive fragments

The FEBS Journal, EarlyView.
The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley   +1 more source

Radioiodination of Two Carborane‐Based Dual Cyclooxygenase‐2/5‐Lipoxygenase Inhibitors and Their In Vitro and In Vivo Evaluation

ChemBioChem, Volume 27, Issue 7, 14 April 2026.
Two dicarbadodecaborane(12)‐based dual cyclooxygenase‐2/5‐lipoxygenase (COX‐2/5‐LO) inhibitors were 123I‐labeled. Refinement of labeling and formulation conditions and extensive in vitro characterization are presented. Cell uptake studies in COX‐2‐ and 5‐LO‐overexpressing cell lines showed COX‐2‐independent and partly 5‐LO‐dependent uptake.
Jonas Schädlich, Martin Ullrich, Cathleen Haase‐Kohn, Robert Wodtke, Sebastian Braun, Maximilian Molitor, Bettina Hofmann, Dieter Steinhilber, Klaus Kopka, Evamarie Hey‐Hawkins, Jens Pietzsch, Markus Laube   +11 more
wiley   +1 more source

In Situ Synthesis of a Tumor Microenvironment‐Activated Radiosensitizing Cu2‐xS/LDH Probe for Photoacoustic Imaging‐Guided Radiotherapy

Advanced Science, Volume 13, Issue 19, 2 April 2026.
We reported a new kind of organic‐inorganic composite nanomaterial with excellent PA imaging performance after the in situ activation by hydrogen sulfide in colorectal cancer tissues, which was used for precise radiotherapy of colorectal cancer. It shows a great application potential for early diagnosis and treatment of tumor.
Kang Zhu, Qiaoqiao Wei, Ying Wu, Qingqing Li, Luntao Liu, Chunxiang Mo, Chuqiao Liu, Lichao Su, Jibin Song   +8 more
wiley   +1 more source

The Hepatocellular Hypoxia Criteria:2’Nitroimidazole Effect on Hepatocyte Carbohydrate Metabolizing Enzymes [PDF]

, 2008
Aim: to understand the 2’-nitroimidazole induced hypoxia and liver cell interaction, we proposed a “Hapatocellular Hypoxia Criteria”.
Rakesh Sharma
core   +1 more source

Primary Pulmonary Adenoid Cystic Carcinoma Managed With Definitive Radiochemotherapy: A Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
Section examined from roght mainstem bronchus showing respiratory lining epithelium, subepithelium showing infiltrative tumor arranged in tubules and cribriform pattern. ABSTRACT Primary pulmonary adenoid cystic carcinoma (ACC) is one of the rare and under‐discussed forms of lung cancer.
Samana Oli, Vivek Ghosh, Asmita Raymajhi, Deepak Jha, Ujjwal Rai, Udip Yadav, Rabindra Sah   +6 more
wiley   +1 more source

Guidelines for nutrition in adults with head and neck cancer: The American Society for Parenteral and Enteral Nutrition

Journal of Parenteral and Enteral Nutrition, Volume 50, Issue 3, Page 274-338, April 2026.
Abstract Background Head and neck cancer represents the seventh most common cancer diagnosis globally. Maintaining sufficient nutrition is important for preventing malnutrition (undernutrition) and muscle wasting, which contribute to worse outcomes, although many patients are unable to maintain adequate oral intake throughout treatment.
Nicole Kiss, Merran Findlay, Jacqui Frowen, Whitney E. Lewis, Jeannine Mills, Anurag K. Singh, David D. Church, Jacob T. Mey, Sarah Peterson, Kathleen Aguzzi, Sarah Bellini, Maria Paula Villela Coelho, Laura Cordwin, Michael Duffy, Shanna Hager, Manpreet S. Mundi, Michael Owen‐Michaane, Kathleen Price, Heather Stanner, Bridget Storm, Malika Udagedara, Liam McKeever   +21 more
wiley   +1 more source

Interference of TiO2 in Fricke Dosimetry: Adsorption Mechanisms and Dose Measurement Challenges under Gamma Irradiation

ChemistryOpen, Volume 15, Issue 4, April 2026.
The presence of TiO2 in Fricke dosimetric systems introduces complex interferences under gamma irradiation. Adsorption of Fe2+/Fe3+ ions, coupled with radiolytic and surface‐mediated processes, alters redox equilibria and apparent absorbed dose values, highlighting critical challenges in chemical dosimetry applied to heterogeneous radiolytic ...
William Villacis, Roque Santos, María Natalia Piol, Paul Vargas‐Jentzsch, Cristina Vázquez   +4 more
wiley   +1 more source

Recent Advances in Hafnium Oxide Nanomaterials: From Controlled Synthesis, Structure, and Surface Engineering to Biomedical Applications

Rare Metals, Volume 45, Issue 4, April 2026.
ABSTRACT Hafnium oxide (HfO2) nanoparticles (NPs), derived from a rare‐metal element, have gained increasing attention as a versatile class of functional nanostructures with unique optical, dielectric, and surface properties that enable diverse biomedical applications. As a representative rare‐metal oxide, HfO2 NPs with well‐defined architectures offer
Mothana Hussein Tarawneh, Mohammed Ali Dheyab, Azhar Abdul Rahman, Mutaz Mohammad Alsardi, Azlan Abdul Aziz, Saleh T. Alanezi, Wesam Abdullah, Sara Abdulwahab, Mehran Ghasemlou   +8 more
wiley   +1 more source