Results 101 to 110 of about 7,625 (228)
Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine
Phytotherapy Research, EarlyView.By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao +11 more
wiley +1 more source
Au@TiO2 Nanocomposites Synthesized by X-ray Radiolysis as Potential Radiosensitizers [PDF]
, 2019 Radiosensitization is a novel targeted therapy strategy where chemical compounds are being explored to enhance the sensitivity of the tissue to the effects of ionizing radiation. Among the different radiosensitizers alternatives, nanomaterials have shown
Molina Higgins, Maria C
core +1 more source
Small, EarlyView.Femtosecond laser ablation of bismuth in acetone yields carbon‐coated nanoparticles with a metallic Bi0 core and an amorphous carbon shell. The core‐shell architecture preserves visible‐light‐driven redox activity and enables sustained hydroxyl‐radical generation.
Pavel Bezrukov +6 more
wiley +1 more source
Enhancement of radiosensitization by metal-based nanoparticles in cancer radiation therapy
Cancer Biology & Medicine, 2014 Radiation therapy performs an important function in cancer treatment. However, resistance of tumor cells to radiation therapy still remains a serious concern, so the study of radiosensitizers has emerged as a persistent hotspot in radiation oncology ...
Xiang-Yu Su +3 more
doaj +1 more source
Stimuli‐responsive nanostructured hydrogen sulfide donors for enhanced cancer treatments
Smart Molecules, EarlyView.Three typical kinds of stimuli‐responsive nanostructured hydrogen sulfide (H2S) donors are reviewed. The nanostructures ensure precise delivery of H2S to the lesion site and regulate the release behavior. The H2S‐based gas therapy has been used to synergize with other cancer treatment modalities, achieving enhanced efficacy while reducing side effects.
Yuxuan Lyu +7 more
wiley +1 more source
ClonoScreen3D - a novel three-dimensional clonogenic screening platform for identification of radiosensitizers for glioblastoma [PDF]
Glioblastoma (GBM) is a lethal brain tumor. Standard of care treatment comprising surgery, radiation and chemotherapy results in median survival rates of 12-15 months.
Caragher, Seamus +6 more
core +2 more sources
Identification of Novel Radiosensitizers in Small Cell Lung Cancer [PDF]
, 2021 Small cell lung cancer (SCLC) is a lethal malignancy, marked by early metastasis into extensive-stage (ES)-SCLC. There is a critical need for improved treatments. After chemotherapy, consolidative thoracic radiotherapy improves patient survival; however,
Shi, Mary Yan
core
Smart Molecules, EarlyView.MOFs offer high porosity and tunability for biomedical applications, especially in cancer therapy via ROS generation and targeted delivery. Though toxicity, stability, and scalability remain key clinical challenges. Drug loading in MOFs exceeds 60%–70% with controlled release behavior.
Jagabandhu Bag +6 more
wiley +1 more source
Antimicrobial applications of inorganic radiosensitizers and their potential in biofilm control. [PDF]
peer reviewedBiofilms are structured microbial communities embedded in a self-produced extracellular matrix. This lifestyle provides significant protection against environmental stressors such as desiccation, chemical treatments and even ionizing ...
Abdeljelil, Nissem +3 more
core +2 more sources
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Hypopharyngeal squamous cell carcinoma (HSCC) is an aggressive subtype of head and neck squamous cell carcinoma with insidious onset, early metastasis, and dismal prognosis. Conventional multimodal therapy achieves limited survival benefit, highlighting an urgent need for refined precision strategies.
Ce Li +12 more
wiley +1 more source