Results 21 to 30 of about 454,799 (340)

Wnt Glycation Inhibits Canonical Signaling

open access: yesCells, 2019
Glycation occurs as a non-enzymatic reaction between amino and thiol groups of proteins, lipids, and nucleotides with reducing sugars or α-dicarbonyl metabolites.
Zhennan Ye   +5 more
doaj   +1 more source

The galectin-3/RAGE dyad modulates vascular osteogenesis in atherosclerosis [PDF]

open access: yes, 2013
Vascular calcification correlates with inflammation and plaque instability in a dual manner, depending on the spotty/granular (micro) or sheet-like/lamellated (macro) pattern of calcification.
BLASETTI FANTAUZZI, Claudia   +9 more
core   +1 more source

Inflammatory signaling of HMGB1 in depressive disorder

open access: yesStress and Brain, 2023
Background:Depressive disorder is a common disease characterized by depressed mood and loss of pleasure, which often brings a great grief to patients and a huge burden to the society.
Qian Jiang   +4 more
doaj   +1 more source

Harken Not to Wild Beasts: Between Rage and Eloquence in Saruman and Thrasymachus [PDF]

open access: yes, 2016
One of the giant gaps in Tolkien scholarship has been to miss how deeply Saruman answers the age-old antagonism between rhetoric and philosophy. Like John Milton, Tolkien cannot bring himself to trust rhetoric.
Wise, Dennis Wilson
core   +2 more sources

Inhibition of RAGE signaling through the intracellular delivery of inhibitor peptides by PEI cationization [PDF]

open access: yes, 2013
The receptor for advanced glycation end products (RAGE) is a multi-ligand cell surface receptor and a member of the immunoglobulin superfamily. RAGE is involved in a wide range of inflammatory, degenerative and hyper-proliferative disorders which span ...
Futami, Jun-Ichiro   +7 more
core   +1 more source

Epidémiologie de la rage et connaissance, attitudes et pratiques des communautés au Burkina Faso

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2020
La rage est une zoonose endémique dans les pays en développement et compte parmi les pathologies virales les plus virulentes et mortelles. Elle constitue une menace pour la sante publique et animale au Burkina Faso.
Madi Savadogo   +8 more
doaj   +1 more source

Brane Inflation from Rotation of D4 Brane [PDF]

open access: yes, 2003
In this paper, a inflationary model from the rotation of D4-brane is constructed. We show that for a very wide rage of parameter, this model satisfies the observation and find that regarded as inflaton, the rotation of branes may be more nature than the ...
Arfaei H.   +6 more
core   +1 more source

Enhanced RAGE Expression and Excess Reactive-Oxygen Species Production Mediates Rho Kinase-Dependent Detrusor Overactivity After Methylglyoxal Exposure

open access: yesFrontiers in Physiology, 2022
Methylglyoxal (MGO) is a highly reactive dicarbonyl compound implicated in diabetes-associated diseases. In vascular tissues, MGO induces the formation of advanced glycation end products (AGEs) that bounds its receptor RAGE, initiating the downstream ...
Akila L. Oliveira   +5 more
doaj   +1 more source

The effects of Danggui-Shaoyao-San on neuronal degeneration and amyloidosis in mouse and its molecular mechanism for the treatment of Alzheimer’s disease [PDF]

open access: yesJournal of Integrative Neuroscience, 2021
The abnormal deposition of the extracellular amyloid-β peptide is the typical pathological hallmark of Alzheimer’s disease. Strategies to reduce the amyloid-β deposition effectively alleviate the neuronal degeneration and cognitive deficits of ...
Cong Yang   +9 more
doaj   +1 more source

Receptor for advanced glycation end products and its involvement in inflammatory diseases [PDF]

open access: yes, 2013
The receptor for advanced glycation end products (RAGE) is a transmembrane receptor of the immunoglobulin superfamily, capable of binding a broad repertoire of ligands. RAGE-ligands interaction induces a series of signal transduction cascades and lead to
Basir, Rusliza   +4 more
core   +3 more sources

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