Wnt Glycation Inhibits Canonical Signaling
Glycation occurs as a non-enzymatic reaction between amino and thiol groups of proteins, lipids, and nucleotides with reducing sugars or α-dicarbonyl metabolites.
Zhennan Ye +5 more
doaj +1 more source
The galectin-3/RAGE dyad modulates vascular osteogenesis in atherosclerosis [PDF]
Vascular calcification correlates with inflammation and plaque instability in a dual manner, depending on the spotty/granular (micro) or sheet-like/lamellated (macro) pattern of calcification.
BLASETTI FANTAUZZI, Claudia +9 more
core +1 more source
Inflammatory signaling of HMGB1 in depressive disorder
Background:Depressive disorder is a common disease characterized by depressed mood and loss of pleasure, which often brings a great grief to patients and a huge burden to the society.
Qian Jiang +4 more
doaj +1 more source
Harken Not to Wild Beasts: Between Rage and Eloquence in Saruman and Thrasymachus [PDF]
One of the giant gaps in Tolkien scholarship has been to miss how deeply Saruman answers the age-old antagonism between rhetoric and philosophy. Like John Milton, Tolkien cannot bring himself to trust rhetoric.
Wise, Dennis Wilson
core +2 more sources
Inhibition of RAGE signaling through the intracellular delivery of inhibitor peptides by PEI cationization [PDF]
The receptor for advanced glycation end products (RAGE) is a multi-ligand cell surface receptor and a member of the immunoglobulin superfamily. RAGE is involved in a wide range of inflammatory, degenerative and hyper-proliferative disorders which span ...
Futami, Jun-Ichiro +7 more
core +1 more source
Epidémiologie de la rage et connaissance, attitudes et pratiques des communautés au Burkina Faso
La rage est une zoonose endémique dans les pays en développement et compte parmi les pathologies virales les plus virulentes et mortelles. Elle constitue une menace pour la sante publique et animale au Burkina Faso.
Madi Savadogo +8 more
doaj +1 more source
Brane Inflation from Rotation of D4 Brane [PDF]
In this paper, a inflationary model from the rotation of D4-brane is constructed. We show that for a very wide rage of parameter, this model satisfies the observation and find that regarded as inflaton, the rotation of branes may be more nature than the ...
Arfaei H. +6 more
core +1 more source
Methylglyoxal (MGO) is a highly reactive dicarbonyl compound implicated in diabetes-associated diseases. In vascular tissues, MGO induces the formation of advanced glycation end products (AGEs) that bounds its receptor RAGE, initiating the downstream ...
Akila L. Oliveira +5 more
doaj +1 more source
The effects of Danggui-Shaoyao-San on neuronal degeneration and amyloidosis in mouse and its molecular mechanism for the treatment of Alzheimer’s disease [PDF]
The abnormal deposition of the extracellular amyloid-β peptide is the typical pathological hallmark of Alzheimer’s disease. Strategies to reduce the amyloid-β deposition effectively alleviate the neuronal degeneration and cognitive deficits of ...
Cong Yang +9 more
doaj +1 more source
Receptor for advanced glycation end products and its involvement in inflammatory diseases [PDF]
The receptor for advanced glycation end products (RAGE) is a transmembrane receptor of the immunoglobulin superfamily, capable of binding a broad repertoire of ligands. RAGE-ligands interaction induces a series of signal transduction cascades and lead to
Basir, Rusliza +4 more
core +3 more sources

