Results 91 to 100 of about 105,143 (344)
Citrate‐Enhanced PCL Scaffolds for Bone Tissue Engineering
Advanced Materials Interfaces, EarlyView.This study investigates citrate‐enhanced polycaprolactone (PCL) scaffolds designed for bone tissue engineering. Utilizing 3D printing technology, four scaffold patterns (triple hexagon, grid, gyroid, zigzag) are evaluated for mechanical properties, cellular proliferation, osteogenic differentiation, and gene expression.
Muge Musmula +6 more
wiley +1 more source
Effects of the anti-RANKL antibody denosumab on joint structural damage in patients with rheumatoid arthritis treated with conventional synthetic disease-modifying antirheumatic drugs (DESIRABLE study): a randomised, double-blind, placebo-controlled phase 3 trial. [PDF]
, 2019 ObjectiveTo evaluate the efficacy of denosumab in suppressing joint destruction when added to conventional synthetic disease-modifying antirheumatic drug (csDMARD) therapy in patients with rheumatoid arthritis (RA).MethodsThis was a multi-centre ...
Genant, Harry K +9 more
core +2 more sources
Impact of Janus Kinase Inhibition with Tofacitinib on Fundamental Processes of Bone Healing [PDF]
, 2020 Both inflammatory diseases like rheumatoid arthritis (RA) and anti-inflammatory treatment of RA with glucocorticoids (GCs) or non-steroidal anti-inflammatory drugs (NSAIDs) negatively influence bone metabolism and fracture healing.
Brinkman, Antonia Clara Katharina +10 more
core +1 more source
The association of osteoprotegerin and RANKL with osteoporosis: a systematic review with meta-analysis [PDF]
, 2023 Guanghao Chi +4 more
openalex +1 more source
Advanced Materials Interfaces, EarlyView.Titanium (Ti) and bismuth (Bi) are selected as alloying elements for the preparation of the Ti‐Bi binary alloy system. Biofilm formation is found to be inhibited by bismuth through the disruption of sulfur metabolism and redox homeostasis, as well as through the direct downregulation of biofilm‐associated proteins.
Lei Shi +10 more
wiley +1 more source
Научно-практическая ревматология, 2014 Objective. To study the effect of infliximab (INF) on serum levels of RANKL and osteoprotegerin (OPG), as well as on structural and functional properties of the vascular wall in patients with rheumatoid arthritis (RA).Material and Methods.
Larisa Aleksandrovna Knyazeva +1 more
doaj +1 more source
RANK and RANKL Expression in Tumors of Patients with Early Breast Cancer [PDF]
, 2023 Annika Behrens +15 more
openalex +1 more source
Advanced Science, EarlyView.This research integrated multi‐omics analysis of bone tissue from HLU and control mice revealed that mechanical unloading suppresses intrinsic apoptosis and augments glutamine (Gln) catabolism in osteoclast lineage cells. The findings highlight pivotal roles for SLC1A5‐mediated Gln metabolism and XIAP/Diablo axis‐mediated apoptosis suppression.
Yi Ding +14 more
wiley +1 more source
Педиатрическая фармакология, 2015 Osteogenesis imperfecta is characterized by increased congenital brittleness of bones with a broad spectrum of clinical manifestations — from perinatal/lethal form and severe bone deformities to the mildest forms.
G. T. Yakhyayeva +2 more
doaj +1 more source
Mechanisms by which sialylated milk oligosaccharides impact bone biology in a gnotobiotic mouse model of infant undernutrition [PDF]
, 2019 Undernutrition in children is a pressing global health problem, manifested in part by impaired linear growth (stunting). Current nutritional interventions have been largely ineffective in overcoming stunting, emphasizing the need to obtain better ...
Ahern, Philip P. +13 more
core +2 more sources