Results 111 to 120 of about 58,241 (294)

Expresión de RANKL y OPG en osteoblastos primarios

, 2012
Objetivo: Los osteoblastos son células especializadas encargadas principalmente de la formación ósea. Además son capaces de modular la osteoclastogénesis a través de la producción de RANKL y OPG.
Riancho JA, Sumillera M, Delgado-Calle J, Sañudo C, Garcés CM   +4 more
core  

Interactive effects of microplastics and arbuscular mycorrhizal fungi on grassland communities

PLANTS, PEOPLE, PLANET, EarlyView.
Grassland plant communities contribute significantly to global biodiversity but face numerous man‐made pressures which may interfere with their ecological functions. One such pressure receiving increasing scientific, political, and public attention is microplastic pollution.
Benedikt Speißer, Yanjie Liu, Mark van Kleunen   +2 more
wiley   +1 more source

Control of RANKL gene expression [PDF]

Bone, 2010
Osteoclasts are highly specialized cells capable of degrading mineralized tissue and form at different regions of bone to meet different physiological needs, such as mobilization of calcium, modeling of bone structure, and remodeling of bone matrix. Osteoclast production is elevated in a number of pathological conditions, many of which lead to loss of ...
openaire   +2 more sources

Therapeutic Properties and Underlying Mechanisms of Traditional Chinese Medicine in Managing Rheumatoid Arthritis: An Integrative Review of Clinical and Molecular Findings

Phytotherapy Research, EarlyView.
The translational research framework integrating TCM for RA. The figure outlines a stepwise framework for the modernization and clinical translation of TCM in RA. Part 1 highlights the inheritance and development of TCM theory, including classical medical texts, traditional herbal knowledge, and syndrome differentiation–based treatment principles. Part
Jianting Wen, Jian Liu, Lei Wan, Fanfan Wang, Yang Li   +4 more
wiley   +1 more source

Catechins and Their Effect on the Gut Microbiome in Health and Cancer

Phytotherapy Research, EarlyView.
ABSTRACT Catechins are a group of flavonoids found primarily in green tea, fruits, and berries; they play a significant role in the modulation of the gut microbiota, thereby having an impact on gut health and cancer prevention. Owing to their low bioavailability, catechins are transformed by the gut microbiota into various bioactive metabolites such as
Prakash Monika, Bindu Sadanandan, Honnamachanahalli Ramachandraiah Tejashree, Maitreyi Darbha, Kirti Gupta, Srinivas Reneeka   +5 more
wiley   +1 more source

Brief an Hans Swarowsky

(15.7.1954) / Karl Rankl. - Typoskript mit eigenhändiger Unterschrift - St. Gilgen, 1954. - 1 Bl.(15.7.1954) / Karl Rankl. - Typoskript mit eigenhändiger Unterschrift - St. Gilgen, 1954.
Rankl, Karl
core   +2 more sources

Disrupted joint clock is associated with rhythmic expression of bone destruction factors in collagen‐induced arthritis

Rheumatology &Autoimmunity, EarlyView.
Schematic Summary of Circadian Dysregulation in Arthritic Joints. This graphical abstract illustrates the key circadian disruptions observed in the collagen‑induced arthritis (CIA) model. The diagram depicts three main findings: (1) Nocturnal elevations in pro‑inflammatory cytokines (TNF‑α, IL‑6, IL‑17, IL‑1β, MIF) and bone‑destructive factors (DKK‑1 ...
Xiaogang Zhang, Mingming Zhang, Zhiqiang Wang, Jie Bai, Xing Feng, Yajing Wang, Zhenbin Li, Dongbao Zhao   +7 more
wiley   +1 more source

Progress in bone tissue engineering biomaterials: Development, challenges, and prospects

VIEW, EarlyView.
Scheme 1 Application of biomaterials in immunomodulation during bone tissue engineering. Abstract Bone defect repair remains a major clinical challenge in orthopedics. Over 2 million cases caused by trauma, tumors, and other factors occur annually, with large‐scale defects posing a particular bottleneck due to limited self‐healing capacity.
Yuanbin Zhang, Junlei Chai, Quanwei Ding, Luping Liu, Kejie Zhang, Jie Lin, Jianhua Zhang, Youju Huang   +7 more
wiley   +1 more source

Clinical Outcomes of the POPCORN Study: Pharmacodynamics of Pre‐Operative PD1 CheckpOint Blockade and Receptor Activator of NF‐κB Ligand (RANKL) Inhibition in Non‐Small Cell Lung Cancer (NSCLC)—A Phase 1B/2 Trial

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Expanding on the growing evidence for neoadjuvant immunotherapy in resectable non‐small cell lung cancer, this study explored neoadjuvant nivolumab ± denosumab. Two of the 10 treated patients achieved a pathological complete response. CD8 T‐cell infiltration correlated with pathological response, warranting ongoing translational research to understand ...
Elizabeth Ahern, Cassie Turner, Rishendran Naidoo, David Godbolt, Amy Ives, Kirsten Popplewell, Zarnie Lwin, Sally Pearson, Kimberley Nelson, Jason Madore, William C Dougall, Brett G. M. Hughes   +11 more
wiley   +1 more source

Cigarette smoke-induced RANKL expression enhances MMP-9 production by alveolar macrophages

, 2018
Lu Zhou,1 Yanqing Le,1 Jieyu Tian,2 Xia Yang,2 Rong Jin,3 Xiaoyan Gai,1 Yongchang Sun1 1Department of Respiratory Medicine, Peking University Third Hospital, Beijing, China; 2Department of Respiratory Medicine, Beijing Tongren Hospital, Capital Medical ...
Tian J, Yang X, Zhou L, Gai X, Jin R, Le Y, Sun Y   +6 more
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