Results 111 to 120 of about 88,529 (348)
Advanced NanoBiomed Research, EarlyView.This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari +5 more
wiley +1 more source
Research Results in PharmacologyIntroduction: N-acetyl-6-aminohexanoate (acexamic acid) and its derivatives are actively studied as promising compounds for the creation of new drugs, but their pharmacokinetic parameters and detailed mechanisms underlying a wide range of biochemical ...
Anton P. Danilenko +17 more
doaj +1 more source
Lattice duality for families of $K3$ surfaces associated to transpose duality [PDF]
, 2016 The aim of this article is to show that the transpose-dual pairs in the sense of Ebeling-Ploog of singularities $(Z_{1,0},\, Z_{1,0})$, $(U_{1,0},\, U_{1,0})$, $(Q_{17},\, Z_{2,0})$, $(W_{1,0},\, W_{1,0})$ that are concluded to be polytope-dual by the ...
Mase, Makiko
core +3 more sources
Control of RANKL gene expression [PDF]
Bone, 2010 Osteoclasts are highly specialized cells capable of degrading mineralized tissue and form at different regions of bone to meet different physiological needs, such as mobilization of calcium, modeling of bone structure, and remodeling of bone matrix. Osteoclast production is elevated in a number of pathological conditions, many of which lead to loss of ...
openaire +2 more sources
Cytokine pathways driving diverse tissue pathologies in rheumatoid arthritis
Arthritis &Rheumatology, Accepted Article.Rheumatoid arthritis is a complex systemic disorder characterised primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease e.g. of the lung with potentially devastating clinical consequences.
Aurelie Najm +2 more
wiley +1 more source
Congenital Adrenal Hyperplasia: A Case Report with Premature Teeth Exfoliation and Bone Resorption [PDF]
, 2015 Congenital adrenal hyperplasia (CAH) is an inherited autosomal recessive disorder characterized by insufficient production of cortisol. The aim of this case report was to present a child with CAH, premature exfoliation of primary teeth and accelerated ...
Angelopoulou, Matina V. +2 more
core +1 more source
Arthritis &Rheumatology, Accepted Article.Objective Bone destruction associated with active rheumatoid arthritis (RA) remains a major therapeutic challenge, with a lack of reliable molecular markers reflecting bone injury. This study aims to identify novel biomarkers linked to bone destruction in active RA through proteomic analysis, providing new strategies for precise monitoring and targeted
Pengfei Xin +15 more
wiley +1 more source
Arthritis &Rheumatology, Accepted Article.Objectives To verify the pathogenesis of the OGFRL1 loss‐of‐function variant (c.30del, p. F10Ffs*110) identified in a CRMO patient and investigate the underlying mechanism. Methods Whole exome sequencing and Sanger sequencing were performed to identify and confirm the variant.
Wen Xiong +9 more
wiley +1 more source
BMEMat, EarlyView.Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu +9 more
wiley +1 more source