Results 201 to 210 of about 41,691 (265)

Aging‐Related Muscle Bmal1 Decline Contributes to Bone Loss in Mice via Enhancing IL‐1α–Mediated Osteoclastogenesis

open access: yesAging Cell, Volume 25, Issue 6, June 2026.
Aging‐related decline of muscle Bmal1 drives bone loss in mice by disrupting Hmox1 and increasing IL‐1α, which promotes osteoclast activity. Time‐restricted feeding reestablishes diurnal Hmox1 expression, reduces IL‐1α, and alleviates osteoporosis, offering a potential therapeutic strategy. ABSTRACT Osteoporosis, a common metabolic bone disorder linked
Kai Huang   +5 more
wiley   +1 more source

Targeting RANKL-independent osteoclastogenesis overcomes denosumab resistance in models of ER+ breast cancer bone metastasis. [PDF]

open access: yesJ Clin Invest
Lin Q   +16 more
europepmc   +1 more source

Biochemical bone biomarkers in plasma cell dyscrasias

open access: yesBritish Journal of Haematology, Volume 208, Issue 6, Page 1909-1923, June 2026.
Visual abstract depicting that bone turnover markers reflect dynamic alterations in bone remodelling across the spectrum of plasma cell dyscrasias but remain limited by assay variability, biological confounding and incomplete integration with imaging and risk stratification.
Guido Nador   +4 more
wiley   +1 more source

Osteocytes in the Metastatic Bone Niche: Mechanistic Pathways and Therapeutic Targets. [PDF]

open access: yesPharmaceuticals (Basel)
Dabaliz A   +4 more
europepmc   +1 more source

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