Results 251 to 260 of about 88,529 (348)

Targeting Delivery of Cyanidin‐Loaded With Ti3C2 Nanosheets for Alleviating Vascular Calcification in Chronic Kidney Disease

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 1, March 2026.
Vascular calcification significantly elevates cardiovascular risk in CKD patients, yet no effective therapies exist to halt its progression. We developed a dual targeting nanoplatform Ti3C2/RANKL/OCN/Cyanidin (TROC) for the targeted delivery of cyanidin against vascular calcification.
Li Yin   +10 more
wiley   +1 more source

Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways. [PDF]

open access: yesMol Med Rep
Wang YH   +7 more
europepmc   +1 more source

RANKL and periodontitis

open access: yesProceedings for Annual Meeting of The Japanese Pharmacological Society, 2022
openaire   +1 more source

Strontium‐Containing Bioactive Glass Nanoparticles Stimulate Osteogenesis and Suppress Osteoclast Formation in Co‐Culture

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 5, 2 February 2026.
Spherical bioactive glass nanoparticles containing strontium inhibit osteoclast differentiation and activity, but promote osteoblast activity in osteoblast‐osteoclast in vitro co‐culture. The nanoparticles could be used for the treatment of osteoporosis.
Parichart Naruphontjirakul   +2 more
wiley   +1 more source

Osteoclast‐Derived SLIT3 Mediates Osteoarthritis Pain and Degenerative Changes

open access: yesAdvanced Science, Volume 13, Issue 7, 3 February 2026.
In TMJ‐OA, osteoclasts play a significant role in promoting the growth of sensory nerves at the osteochondral interface. In early OA, TRAP+ osteoclast‐derived SLIT3 induces sensory nerve growth into the condylar cartilage. This nerve growth facilitates the development of pain associated with OA.
Weiwei Zhu   +13 more
wiley   +1 more source

Presenilin L166P Mutation, a Model of Familial Alzheimer's Disease, Leads to Early Onset Bone Loss

open access: yesComprehensive Physiology, Volume 16, Issue 1, February 2026.
Female‐specific bone loss in Alzheimer's disease mouse models: There is a significant alteration of bone phenotype during Alzheimer's disease. Using integrated imaging and biological assays, we observed changes in the bone microarchitecture, composition, and function in PSEN K1 and PSEN1/hAPP Tg+ mice, predominantly in the females. ABSTRACT Accelerated
Vidyani Suryadevara   +12 more
wiley   +1 more source

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