Results 61 to 70 of about 359,204 (269)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Comparing RAS with and without biofloc: transcriptional response of immune-related genes in Litopenaeus vannamei post-larvae

Revista Colombiana de Ciencias Pecuarias, 2020
Background: Shrimp farming is evolving from semi-intensive to hyper-intensive systems with biofloc technology and water recirculation systems. Objective: To evaluate the transcriptional response promoted by biofloc on shrimp (Litopenaeus vannamei) under ...
Jorge Soto Alcalá, Píndaro Álvarez Ruiz, Juan M. Audelo Naranjo, Héctor M. Esparza Leal, Irasema E. Luis Villaseñor, José A. Estrada-Godínez, Antonio Luna-González, Carina Gámez-Jiménez, Genaro Diarte Plata   +8 more
doaj   +1 more source

Ras and Ras mutations in cancer

Open Life Sciences, 2013
Abstract Ras genes are pre-eminent genes that are frequently linked with cancer biology. The functional loss of ras protein caused by various point mutations within the gene, is established as a prognostic factor for the genesis of a constitutively active Ras-MAPK pathway leading to cancer. Ras signaling circuit follows a complex pathway,
Rajasekharan Satish, Raman Thiagarajan
openaire   +2 more sources

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Impact of Streptomyces and Bacillus on Ammonia, Nitrite, Vibrio Counts and Growth of Penaeus vannamei in Recirculating Aquaculture System

Journal of Pure and Applied Microbiology
This study evaluates the effects of supplementing whiteleg shrimp (Penaeus vannamei) feed with Streptomyces strains (TM1, TM2, TM7, TM21, TM22), Bacillus strains (AQ1, BIO2, BAL3), and their combinations at different densities (106, 107, and 108 CFU/g ...
To Dinh Phuc, Nguyen Thuy Huong, Pham Minh Tuan, Huynh Thai Truc Linh, Nguyen Thi Ngoc Han, Pham Thi Thu Dan, Bui Thi Hong Linh   +6 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Effects of Seed Transfer Distance on Production Success of Mud Crab (Scylla serrata) in Recirculating Aquaculture Systems

Aquatic Sciences and Engineering
Mud crab (Scylla serrata) culture using recirculating aquaculture systems (RAS) with vertical crab boxes offers a sustainable model for urban aquaculture, particularly in land-limited coastal cities such as Jakarta, Indonesia.
Irzal Effendi, Erwan Rusdiawan, Iis Diatin, Belinda Astari   +3 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

EVALUACIÓN DE CALIDAD DE AGUA RESIDUAL TRATADA PARA RIEGO EN EL VALLE ALTO DE LA CIUDAD DE COCHABAMBA

Investigación & Desarrollo
El presente estudio se enfoca en analizar la calidad fisicoquímica de los efluentes generados por un grupo de Plantas de Tratamiento de Aguas Residuales (PTAR) situadas en el Valle Alto de Cochabamba para determinar su aptitud de reúso agrícola.
Ivette Echeverría, Gabriel Aliaga, Oliver Saavedra   +2 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source