Results 101 to 110 of about 798,166 (289)

Heterophyllin B Ameliorates Lipopolysaccharide-Induced Inflammation and Oxidative Stress in RAW 264.7 Macrophages by Suppressing the PI3K/Akt Pathways

Molecules, 2018
Heterophyllin B (HB), an active cyclic peptide, is a compound existing in the ethyl acetate extract of Pseudostellaria heterophylla (Miq.) Pax and exhibited the activity of inhibiting the production of NO and cytokines, such as IL-1β and IL-6, in LPS ...
Chunjing Yang, Longtai You, Xingbin Yin, Yi Liu, Xin Leng, Wenping Wang, Na Sai, Jian Ni   +7 more
doaj   +1 more source

The effect of MEO on NO and PGE2 production of LPS-stimulated RAW 264.7 macrophage cells.

, 2014
(A) represents the inhibitory effect of NO production, (B) represents the inhibitory effect of MEO on PGE2 production; and (C) indicates the cytotoxic effect of MEO on RAW 264.7 cells. Results are mean ± SD (n = 3).
Jing Wang (4865), Lianming Zhou (672949), Peiming Yang (672950), Zhenliang Sun (672948), Huiyan Wang (350287)   +4 more
core   +1 more source

Restoring Endothelial Mitochondrial Homeostasis With a Bioactive Nanoshield Promotes Vascular Regeneration on Cardiovascular Implants

Advanced Science, EarlyView.
A bioactive poly(citrate‐polyglycol‐procyanidin) (PCGP) nanoshield is developed for cardiovascular implants to restore endothelial mitochondrial homeostasis following vascular injury. By preserving mitochondrial integrity, re‐establishing metabolic balance, and activating PI3K/Akt/eNOS‐NO signaling, the PCGP interface promotes functional endothelial ...
Xiyu Liu, Wen Zhang, Lunxin Liu, Lan Gui, Yumei Qin, Xiaohui Yang, Longjian Zhang, Chaohua Wang, Jinpeng Hu, Gaoyang Guo, Qing Jiang, Jin Wang, Li Yang, Bo Zhang, Yunbing Wang   +14 more
wiley   +1 more source

Additional file 10: of Global gene-expression profiles of intracellular survival of the BruAb2_1031 gene mutated Brucella abortus in professional phagocytes, RAW 264.7 cells

, 2018
Table S5. The genes showing altered expression in RAW 264.7 cells after C30 mutant strain infection. The different expression levels in B. abortus C30 mutant strain infected RAW 264.7 cells were compared to wild-type infected cells.
Myunghwan Jung (691208), Soojin Shim (1848115), Woo Park (5577119), Han Yoo (5577122), Young Im (5577113)   +4 more
core   +1 more source

Multifunctional Zinc Glycyrrhizinate‐Integrated Gel for Enhanced Probiotic Delivery and Alleviation of Acute and Spontaneous Colitis

Advanced Science, EarlyView.
Multifunctional oral delivery system—L. reuteri@ZGM—act as both a carrier and therapeutic adjuvant, providing ROS scavenging, and mucin‐interactive properties tailored to the IBD microenvironment. This bioactive gel safeguards L. reuteri from gastric degradation, enhances mucosal adhesion, and promotes long‐term retention at inflamed sites, thereby ...
Mengyun Peng, Xiaochun Chen, Wei Li, Shu Tang, Jun Zhou, Xia Wu, Dan Yuan, Zhongyan Shan, Junfeng Shi   +8 more
wiley   +1 more source

Regulation of Inflammation by Sucrose Isomer, Turanose, in Raw 264.7 Cells

Journal of Cancer Prevention, 2017
Increased sugar consumption has been proposed to be a risk factor for obesity-related metabolic disorders. The objective of this study was to investigate the anti-inflammatory effect of turanose in Raw 264.7 macrophages. Turanose (3-O-α-D-glucosyl-D-fructose), an isomer of sucrose, naturally exists in honey.
Chung, Joo-Yeon, Kim, Yoo-Sun, Kim, Yuri, Yoo, Sang-Ho   +3 more
openaire   +3 more sources

Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair

Advanced Science, EarlyView.
Schematic diagram illustrating the Dab1‐linked hypoxia signaling pathway that accelerates angiogenesis and consequent nerve regeneration. Following PNI, a hypoxic microenvironment develops. Hypoxia induces macrophage Dab1 phosphorylation, resulting in NHE‐1 upregulation, HIF‐1α stabilization, and VEGF‐A expression. This cascade promotes angiogenesis in
Xiongyao Zhou, Fan Zhang, Jiangbo Wang, Huiyuan Wang, Zongqiang Wang, Qianqian Wang, Chuikai Meng, Jialu Sun, Han Wang, Weiye Li, Ziyi Zhao, Le Qi, Xiaosong Gu, Shusen Cui, Rangjuan Cao   +14 more
wiley   +1 more source

2-Bromo-5-Hydroxy-4-Methoxybenzaldehyde Exhibits Anti-Inflammatory Effects Through the Inactivation of ERK, JNK, and NF-kB Pathways in RAW 264.7 Cells

Phycology
Inflammation plays a central role in the pathogenesis of numerous diseases through the excessive production of nitric oxide (NO), prostaglandins, and pro-inflammatory cytokines.
Junseong Kim, Seong-Yeong Heo, Eun-A Kim, Nalae Kang, Soo-Jin Heo   +4 more
doaj   +1 more source

Beyond Biomimetics: Pathology‐Informed Engineering Rescues Reconstituted HDL From Inflammatory Dysfunction for Sepsis Immunotherapy

Advanced Science, EarlyView.
A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou, Lei Zhang, Xingyu Cai, Jiajia Su, Guangyu Dai, Xue Chen, Hanming Wang, Jia Hua, Jianping Liu, Chunmeng Sun, Xiancheng Chen, Erhao Wang, Wenli Zhang   +12 more
wiley   +1 more source

Primed B cells induced the expression of M2 macrophage in RAW 264.7 cells and DH82 cells.

, 2021
LPS stimulated RAW 264.7 and DH82 cells were co-cultured with primed B cells for 48 h (Scale bar, 100um). (A) Representative immunofluorescence staining using anti-CD11b-PE or anti-CD206-FITC positive cell in RAW 264.7 cells (B) Representative ...
Ju-Hyun An (5795309), Hwa-Young Youn (713961), Kyeong Bo Kim (11740640), Hee-Won Jang (11740637), Su-Min Park (11185660), Ye-In Oh (9369770), Hyung-Kyu Chae (11185663), Jeong-Hwa Lee (6701528)   +7 more
core   +1 more source