Results 11 to 20 of about 39,925 (149)

Red Blood Cell Alloimmunization and Its Associated Factors among Chronic Liver Disease Patients in a Teaching Hospital in Northeastern Malaysia

Diagnostics, 2023
Red blood cell (RBC) alloimmunization is an important complication of blood transfusion. Variations in the frequency of alloimmunization have been noted among different patient populations. We aimed to determine the prevalence of RBC alloimmunization and
Siti Zaleha S. Abdullah, Mohd Nazri Hassan, Marini Ramli, Marne Abdullah, Noor Haslina Mohd Noor   +4 more
doaj   +2 more sources

The Nlrp3 Inflammasome Does Not Regulate Alloimmunization to Transfused Red Blood Cells in Mice [PDF]

EBioMedicine, 2016
Red blood cell (RBC) transfusions are essential for patients with hematological disorders and bone marrow failure syndromes. Despite ABO matching, RBC transfusions can lead to production of alloantibodies against “minor” blood group antigens.
David R. Gibb, Samuele Calabro, Dong Liu, Christopher A. Tormey, Steven L. Spitalnik, James C. Zimring, Jeanne E. Hendrickson, Eldad A. Hod, Stephanie C. Eisenbarth   +8 more
doaj   +2 more sources

The Nrf2 Activator CDDO-Imidazole Suppresses Inflammation-Induced Red Blood Cell Alloimmunization

Antioxidants
Experimental Objective: During red blood cell (RBC) transfusion, inflammation promotes the production of anti-RBC alloantibodies that can cause significant hemolytic events.
Che-Yu Chang, Rosario Hernández-Armengol, Kausik Paul, June Young Lee, Karina Nance, Tomohiro Shibata, Peibin Yue, Christian Stehlik, David R. Gibb   +8 more
doaj   +2 more sources

Red cell alloimmunization in multitransfused hepatobiliary patients at hospital Selayang

Asian Journal of Transfusion Science
BACKGROUND: Transfusion support is vital for the management of patients with hepatobiliary disease. Repeated blood transfusions increase the risk of alloimmunization, i.e., the development of alloantibodies, which might lead to difficulties in blood ...
Prasanthini Nahendran, Siti Balkis Budin, Nur Zakiah Mohd Saat, Mohd Faeiz Yusop, Tengku Norita Tengku Yazid, Nur Najmi Mohamad Anuar   +5 more
doaj   +2 more sources

Transforming growth factor-β released by apoptotic white blood cells during red blood cell storage promotes transfusion-induced alloimmunomodulation.: Apoptotic WBC limit RBC alloimmunization

, 2015
International audienceRed blood cell (RBC) alloimmunization is a major immunologic risk of transfusion. However, RBC storage facilitates white blood cell (WBC) apoptosis and apoptotic cells have immunomodulatory properties.
Perruche, Sylvain, Daoui, Anna, Saas, Philippe, Tiberghien, Pierre, Vallion, Romain, Vieille, Loredane, Bonnefoy, Francis   +6 more
core   +10 more sources

Alloimmunization in thalassemia patients: New insight for healthcare

International Journal of Preventive Medicine, 2017
Background: Development of alloantibodies against the foreign red blood cell (RBC) (alloimmunization) is a well-known complication in thalassemia patients when performing multiple transfusions.
Ali Davoudi-Kiakalayeh, Reza Mohammadi, Ali Akbar Pourfathollah, Zahra Siery, Sajad Davoudi-Kiakalayeh   +4 more
doaj   +2 more sources

Frequency of Red Blood Cell Alloimmunization in Patients with Sickle Cell Disease in Palestine

Advances in Hematology, 2018
Background. Transfusion of red blood cells (RBC) is an essential therapeutic tool in sickle cell disease (SCD). Repeated RBC transfusions can cause alloimmunization which causes difficulty in cross-matching and finding compatible blood for transfusions ...
Fekri Samarah, Mahmoud A. Srour, Dirgham Yaseen, Kamal Dumaidi   +3 more
doaj   +2 more sources

The Association of CD81 Polymorphisms with Alloimmunization in Sickle Cell Disease [PDF]

Clinical and Developmental Immunology, 2013
The goal of the present work was to identify the candidate genetic markers predictive of alloimmunization in sickle cell disease (SCD). Red blood cell (RBC) transfusion is indicated for acute treatment, prevention, and abrogation of some complications of
Zohreh Tatari-Calderone, Ryad Tamouza, Gama P. Le Bouder, Ramita Dewan, Naomi L. C. Luban, Jacqueline Lasserre, Jacqueline Maury, François Lionnet, Rajagopal Krishnamoorthy, Robert Girot, Stanislav Vukmanovic   +10 more
doaj   +2 more sources

Alloimmunization in Pregnancy: A Practical Guide for Transfusion Medicine

Hemato
Background: Feto-maternal hemorrhages (FMHs) due to placenta disruption and bleeding from fetal maternal circulation can lead to life-threatening fetal anemia. These hemorrhages are more often of small volume and remain unreported. Sensitization to fetal
Palma Manduzio, Luigi Ciccone, Valeria Cosima Elisena Cardo, Antonietta Faleo, Antonietta Ferrara, Lucia Simone, Libera Padovano, Tommaso Granato   +7 more
doaj   +2 more sources

Red Blood Cell Alloimmunization in Pediatric group with Beta Thalassemia: A Five-Year Experience

Global Pediatric Health, 2022
Beta-thalassemia is one of the most frequently occurring hematological disorders in [Removed for blinded peer-review]. Regular blood transfusion is required in almost all cases for management.
Kiran Minhas MBBS FCPS, Muzamil Shabana Ejaz MBBS MCPS DCH FCPS, Alaa Tukruna MD, Maryam Haider MBBS FCPS, Aabiya Arif MBBS, Sameer Saleem Tebha MBBS   +5 more
doaj   +1 more source