Results 21 to 30 of about 39,925 (149)

IMPACT OF PROPHYLACTIC RED BLOOD CELL (RBC) TRANSFUSION WITH EXTENDED ANTIGEN MATCHING ON ALLOIMMUNIZATION IN PATIENTS WITH SICKLE CELL DISEASE (SCD)

Hematology, Transfusion and Cell Therapy, 2021
Background: RBC alloimmunization remains a significant problem for many patients with SCD. To reduce alloimmunization some strategies have been implemented to provide limited (C/c, E/e, K) or extended antigen matched (C/c, E/e, K, Fya/b, Jka/b, S/s) RBC ...
MR Miranda, I Leal, TDD Santos, S Gilli, L Castilho   +4 more
doaj   +1 more source

RBC Alloimmunization in Sudanese Multi-transfused Patients [PDF]

Journal of Bioscience and Applied Research, 2020
Background: Blood transfusions are a life-saving measure to replace blood lost through severe bleeding or as a life-saving treatment for various hematological conditions. Blood transfusions are high-risk procedures. One of these risks is alloimmunization.
Hager Elkobani, Sahar Elbager, Magdi Bayoumi   +2 more
doaj   +1 more source

TRANSFUSION PRACTICE, POST-TRANSFUSION COMPLICATIONS AND RISK FACTORS IN SICKLE CELL DISEASE IN SENEGAL, WEST AFRICA.

Mediterranean Journal of Hematology and Infectious Diseases, 2022
Context and Objectives: Blood transfusions (BT) remain a mainstay of therapy for patients with sickle cell disease (SCD), but pose significant clinical challenges. We aim to assess infectious markers, red cell alloimmunization and iron overload secondary
Moussa Seck, Alioune Badara Senghor, Mossane Loum, Sokhna Aissatou Touré, Blaise Félix Faye, Alioune Badara Diallo, Mohamed Keita, Elimane Seydi Bousso, Sérigne Mourtalla Guèye, Macoura Gadji, Abibatou Sall, Awa Oumar Touré, Saliou Diop   +12 more
doaj   +1 more source

The impact of pre-existing HLA and red blood cell antibodies on transfusion support and engraftment in sickle cell disease after nonmyeloablative hematopoietic stem cell transplantation from HLA-matched sibling donors: A prospective, single-center, observational study

EClinicalMedicine, 2020
Background: Hematopoietic stem cell transplantation (HSCT) is curative for patients with sickle cell disease (SCD). Prior to HSCT, patients with SCD commonly receive RBC transfusions with some becoming RBC or HLA alloimmunized.
Robert Sheppard Nickel, Willy A. Flegel, Sharon D. Adams, Jeanne E. Hendrickson, Hua Liang, John F. Tisdale, Matthew M. Hsieh   +6 more
doaj   +1 more source

DataSheet_1_FcγRIV is required for IgG2c mediated enhancement of RBC alloimmunization.docx

, 2022
Passive immunization with anti-D can prevent maternal alloimmunization to RhD thereby preventing hemolytic disease of the fetus and newborn. Unexpectedly, anti-D fails in some cases and some monoclonal anti-D preparations paradoxically enhances ...
Manjula Santhanakrishnan (11025033), James C. Zimring (8785304), Annie Qiu (10294481), Jeanne E. Hendrickson (5364113), Chance John Luckey (10294484), Anabel Miller (13795351), Maria Tredicine (11280165), Flavia Dei Zotti (12237368), Krystalyn E. Hudson (5821964), Sean R. Stowell (8948291)   +9 more
core   +1 more source

Alloimmunization to erythrocyte antigens in patients receiving multiple blood transfusions: Clinico-immunohematological and demographic risk factors and impact of extended red cell phenotyping

Global Journal of Transfusion Medicine, 2021
Background and Objectives: The risk of red blood cell (RBC) alloimmunization is always a concern for multi-transfused patients. Various factors have been found to be associated with alloimmunization. Alloimmunization rates were reported from 4% to 50%, 1.
Sudipta Sekhar Das, Rathindra Nath Biswas, Mahammad Safi, Rafique Uz Zaman   +3 more
doaj   +1 more source

The prevalence of cumulative alloimmunization in patients with sickle cell disease at King Fahad University Hospital

Journal of Applied Hematology, 2022
BACKGROUND: Sickle cell disease (SCD) is caused by a mutation in the beta-globin gene. Red blood cell (RBC) transfusion is considered the mainstay of management.
Rabab Ahmad AlDawood
doaj   +1 more source

Prevalence and Specificity of RBC Alloantibodies in Indian Patients Attending a Tertiary Care Hospital

Advances in Hematology, 2014
Background. Red blood cell (RBC) alloimmunization results from genetic disparity of RBC antigens between donor and recipients. Data about alloimmunization rate in general patient population is scarce especially from resource limited countries.
Shamsuz Zaman, Rahul Chaurasia, Kabita Chatterjee, Rakesh Mohan Thapliyal   +3 more
doaj   +1 more source

RBC-only simulations in straight channels with different channel widths and RBC densities.

, 2023
(A) The steady-state density of RBC distribution in a wider channel with a width of 31μm. (B) The steady-state density of RBC distribution in a narrower channel with a width of 20μm using the same RBC density as in (A).
Thomas G. Fai (4500571), Ying Zhang (40767)   +1 more
core   +1 more source

Frequency of Red Cell Alloimmunization and Autoimmunization in Thalassemia Patients: A Report from Eastern India

Advances in Hematology, 2015
Introduction. Red blood cell (RBC) alloimmunization and autoimmunization remain a major problem in transfusion dependent thalassemic patients. There is a paucity of data on the incidence of RBC alloimmunization and autoimmunization in thalassemic ...
Suvro Sankha Datta, Somnath Mukherjee, Biplabendu Talukder, Prasun Bhattacharya, Krishnendu Mukherjee   +4 more
doaj   +1 more source