Results 1 to 10 of about 98,712 (50)
BackgroundNeuronal intranuclear inclusion disease (NIID) is a progressive neurodegenerative disease associated with the GGC repeats in the 5'-untranslated region (5'UTR) of NOTCH2NLC. NIID exhibits a wide range of clinical manifestations.
Fei Xie, Xingyue Hu, Peng Liu, Dan Zhang
doaj +1 more source
Risk of Incident Epilepsy After a Middle Cerebral Artery Territory Infarction
BackgroundAmong poststroke morbidities, poststroke epilepsy (PSE) has been identified as a significant clinical issue. Although middle cerebral artery (MCA) infarct is the most common type of stroke among all vascular territories, very few studies ...
Cheng-Yang Hsieh+9 more
doaj +1 more source
Non-human primate pluripotent stem cells for the preclinical testing of regenerative therapies
Non-human primates play a key role in the preclinical validation of pluripotent stem cell-based cell replacement therapies. Pluripotent stem cells used as advanced therapy medical products boost the possibility to regenerate tissues and organs affected ...
Ignacio Rodriguez-Polo, Rüdiger Behr
doaj +1 more source
Brain barriers virtual: an interim solution or future opportunity?
Background Scientific conferences are vital communication events for scientists in academia, industry, and government agencies. In the brain barriers research field, several international conferences exist that allow researchers to present data, share ...
Brianna M. Holder+14 more
doaj +1 more source
Bone marrow-derived mononuclear stem cells in the treatment of retinal degenerations
Retinal degenerative diseases affecting the outer retina in its many forms (inherited, acquired or induced) are characterized by photoreceptor loss, and represent currently a leading cause of irreversible vision loss in the world.
Diego Garcia-Ayuso+4 more
doaj +1 more source
Ruxolitinib attenuates secondary injury after traumatic spinal cord injury
Excessive inflammation post-traumatic spinal cord injury (SCI) induces microglial activation, which leads to prolonged neurological dysfunction. However, the mechanism underlying microglial activation-induced neuroinflammation remains poorly understood ...
Zhan-Yang Qian+11 more
doaj +1 more source
In our previous studies, we have shown that (D-Ser2) oxyntomodulin (Oxm), a glucagon-like peptide 1 (GLP-1) receptor (GLP1R)/glucagon receptor (GCGR) dual agonist peptide, protects hippocampal neurons against Aβ1–42-induced cytotoxicity, and stabilizes ...
Guang-Zhao Yang+12 more
doaj +1 more source
ObjectiveThe characteristics of the upper airway (UA) are important for the evaluation and treatment of obstructive sleep apnea (OSA). This study aimed to investigate the association of UA characteristics with OSA severity, titration pressure, and ...
Cheng Zhang+5 more
doaj +1 more source
BackgroundThis study aimed to investigate clinical and angiographic outcomes of Pipeline embolization device (PED) treatment of large or giant basilar artery (BA) aneurysms and examine associated factors.MethodsClinical and angiographic data of 29 ...
Huijian Ge+22 more
doaj +1 more source
BackgroundCharacterization of the clot occluding the arteries in acute ischemic stroke received ample attention, in terms of elucidating the relationship between the clot composition, its etiology and its amenability for pharmacological treatment and ...
Daniela Dumitriu LaGrange+19 more
doaj +1 more source