Results 41 to 50 of about 130,598 (99)

A companion to the preclinical common data elements for rodent models of pediatric acquired epilepsy: A report of the TASK3‐WG1B, Pediatric and Genetic Models Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open
Epilepsy syndromes during the early years of life may be attributed to an acquired insult, such as hypoxic–ischemic injury, infection, status epilepticus, or brain trauma.
Anna‐Maria Katsarou, Hana Kubova, Stéphane Auvin, Massimo Mantegazza, Melissa Barker‐Haliski, Aristea S. Galanopoulou, Christopher A. Reid, Bridgette D. Semple   +7 more
doaj   +1 more source

The influence of direct transportation to neurosurgical-capable medical centers on the clinical outcomes of patients with spontaneous intracerebral hemorrhage in urban area: a two-center retrospective study

Frontiers in Neurology
IntroductionSpontaneous intracranial hemorrhage (ICH) is one of the major causes of morbidity and mortality worldwide due to its poor clinical outcomes.
Zijian Chen, Haibo Li, Zhaodi Liao, Xuexiang Shen, Peizhi Qin, Wei Ji, Yuanrun Zhu   +6 more
doaj   +1 more source

MiR‐429 suppresses proliferation and invasion of breast cancer via inhibiting the Wnt/β‐catenin signaling pathway

Thoracic Cancer, 2020
microRNAs (miRNAs) have been verified as molecular targets for regulating tumor proliferation, invasion, and metastasis in tumor progression. However, the relationship between miRNAs and cellular energy metabolism in breast cancer still needs to be ...
Liping Zhang, Qinghua Liu, Qingjie Mu, Dandan Zhou, Hongli Li, Baogang Zhang, C. Yin   +6 more
semanticscholar   +1 more source

Generation of a new Slc20a2 knockout mouse line as in vivo model for primary brain calcification

Molecular Brain
Primary brain calcification (PBC) is a neurodegenerative disease that causes bilateral ectopic calcification in the brain. In this study, using newly generated Slc20a2 knockout (Slc20a2 −/−) mice, we establish an in vivo model for PBC.
Hisaka Kurita, Hiroki Kitaura, Kazuya Nishii, Tomohiko Masaka, Kazuki Ohuchi, Masatoshi Inden, Akiyoshi Kakita, Masatake Osawa, Isao Hozumi   +8 more
doaj   +1 more source

Machine learning identifies neutrophil extracellular traps-related biomarkers for acute ischemic stroke diagnosis

Frontiers in Neurology
PurposeThis study aimed to investigate the diagnostic potential of neutrophil extracellular traps (NETs)-related genes in acute ischemic stroke (AIS) through comprehensive bioinformatics analysis.MethodsTwo GEO datasets (GSE37587 and GSE16561) were ...
Haipeng Zhang, Ti Wu, Xinghua Li, Shuangqing Liu, Yuanyuan Wang, Yang Cao   +5 more
doaj   +1 more source

NOD2 promotes dopaminergic degeneration regulated by NADPH oxidase 2 in 6-hydroxydopamine model of Parkinson’s disease

Journal of Neuroinflammation, 2018
Background In Parkinson’s disease (PD), loss of striatal dopaminergic (DA) terminals and degeneration of DA neurons in the substantia nigra (SN) are associated with inflammation. Nucleotide-binding oligomerization domain-containing protein (NOD)2, one of
Li Cheng, Lin Chen, Xinbing Wei, Yimeng Wang, Zhiping Ren, Shenglan Zeng, Xiumei Zhang, Haitao Wen, Chengjiang Gao, Huiqing Liu   +9 more
doaj   +1 more source

Social inference brain networks in autistic adults during movie-viewing: functional specialization and heterogeneity

Molecular Autism
Background Difficulty in social inferences is a core feature in autism spectrum disorders (ASD). On the behavioral level, it remains unclear whether reasoning about others’ mental states (Theory of Mind, ToM) and empathic responses to others’ physical ...
Jasmin M. Turner, Lisa Byrge, Hilary Richardson, Paola Galdi, Daniel P. Kennedy, Dorit Kliemann   +5 more
doaj   +1 more source

Functional near-infrared spectroscopy for identifying mild cognitive impairment and Alzheimer’s disease: a systematic review

Frontiers in Neurology
BackgroundFunctional Near-Infrared Spectroscopy (fNIRS) has been used to detect changes in haemodynamic response in patients with neurodegenerative diseases such as Alzheimer’s disease (AD) and mild cognitive impairment (MCI).
Haoyu Li, Xi Yang, Liang Gong
doaj   +1 more source

Theranostic application of miR-429 in HER2+ breast cancer

Theranostics, 2020
Human epidermal growth factor receptor 2 (HER2) is overexpressed/amplified in one third of breast cancers (BCs), and is associated with the poorer prognosis and the higher metastatic potential in BC.
C. Cava, C. Novello, C. Martelli, A. Lo Dico, L. Ottobrini, F. Piccotti, M. Truffi, F. Corsi, G. Bertoli, I. Castiglioni   +9 more
semanticscholar   +1 more source

Flexible and Adjustable Transparent Sheath Endoport combine with “two-in-one” neuroendoscopic for minimally invasive evacuation of irregular intracerebral hemorrhage

Frontiers in Neurology
ObjectiveIrregular intracerebral hematomas (ICH), characterized by complex shapes or multi-regional involvement, pose challenges for traditional neuroendoscopy due to rigid endoport limitations.
Zohaib Shafiq, Wenju Wang, Long Zhou, Zhiyang Li, Ping Song, Silei Zhang, Qiang Cai   +6 more
doaj   +1 more source